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greater decrease » greatest decrease (Expand Search), greater increase (Expand Search), greater disease (Expand Search)
marked decrease » marked increase (Expand Search)
large decrease » larger decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
aged greater » fold greater (Expand Search), a greater (Expand Search), face greater (Expand Search)
greater decrease » greatest decrease (Expand Search), greater increase (Expand Search), greater disease (Expand Search)
marked decrease » marked increase (Expand Search)
large decrease » larger decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
aged greater » fold greater (Expand Search), a greater (Expand Search), face greater (Expand Search)
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<b>Effect of Marked Weight Loss on Adipose Tissue Biology in People with Obesity and Type 2 Diabetes</b>
Published 2025“…</p><p dir="ltr"><b>Results: </b>Weight loss: <a href="" target="_blank">i) </a><a href="" target="_blank">decreased adipose tissue </a>expression of genes related to extracellular matrix remodeling; ii) decreased adipose tissue expression of SERPINE 1 which encodes plasminogen activator inhibitor-1 (PAI-1); iii) did not decrease adipose tissue immune cell content or expression of genes involved in inflammation; iv) decreased adipose tissue ceramide content; v) decreased plasma <a href="" target="_blank">PAI-1 </a>and leptin concentrations and increased plasma high-molecular weight (HMW) adiponectin; and vi) decreased plasma small extracellular vesicle (sEV) concentration and the sEV content of microRNAs proposed to inhibit insulin action, and completely reversed the inhibitory effect of plasma sEVs on insulin signaling in myotubes.…”
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Occurrence of subcortical immature neurons (scINs) in the amygdala of mouse and primates: relationship with evolution of subnuclei scaling and cortical connectomics.
Published 2025“…<b>(B)</b> After scIN total amount estimation in the amygdala of each hemisphere (young adult age group, top), chimpanzees possess a reservoir of undifferentiated cells four orders of magnitude higher than mice, and this reservoir is maintained through ages in primates, while decreasing in rodents (bottom; quantitative data extracted from <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003322#pbio.3003322.s012" target="_blank">S5 Table</a>). …”