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large decrease » large increases (Expand Search), large degree (Expand Search)
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large decrease » large increases (Expand Search), large degree (Expand Search)
increase » increased (Expand Search)
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Simplified scheme illustrating the inhibitory effect of nNOS on the PPP during the initiation of GSIS.
Published 2025“…<p>1) A marked increase in glucose concentration results in a large accumulation of the released insulin at the exocytotic sites of nNOS-associated insulin granules (denoted as orange circles on insulin granules) in the PPP. …”
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S1 File -
Published 2025“…Culturing at high glucose increased both nNOS and iNOS activities inducing a marked decrease in GSIS in a following short-term incubation at high glucose. …”
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