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Increasing the Scale of the Mass Spectrometry Query Language Compendium with Explainable AI
Published 2025Subjects: -
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20E repressed ILP-mediated cell membrane translocation of HaP60 and HaP110, dephosphorylated HaP60 and HaP110, and decreased their interaction.
Published 2021“…<p><b>A and B.</b> Immunocytochemistry showed that 20E repressed insulin-mediated HaP60 and HaP110 cell membrane localization in HaEpi cells by dephosphorylating HaP60 and HaP110. …”
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ALS patients’ tissues exhibit increased phosphorylation of MARK2.
Published 2021“…<p>(<b>A</b>) Representative immunoblot analyses of PKCδ, MARK2-<sup>595</sup>T, and eIF2α in the spinal cord tissues from ALS patients and non-ALS controls, indicating that increased phosphorylation of PKCδ-<sup>505</sup>T, MARK2-<sup>595</sup>T, and eIF2α-<sup>51</sup>S is a general phenotype in patient tissues. …”
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Deletion of Hhp2 markedly increased Sre1 activity.
Published 2020“…<p>Deletion of <i>hhp2</i><sup>+</sup> gene markedly increased Sre1 activity in the presence/absence of CLZ (2 μg/ml to 8 μg/ml) (A), TER (2 μg/ml to 8 μg/ml) (B) or CoCl<sub>2</sub> (0.08 mM to 0.32 mM) (C). …”
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<i>In vitro</i> characterization of escape mutant viruses of anti-HA stalk antibody candidate clone F11.
Published 2021“…(B) Recombinant trimeric HA proteins harboring each mutation (T333K (mutant C) or G480D (mutant G)) were tested in a binding assay with F11 IgG1 to examine whether the mutations in the HA gene of escape mutant viruses affected the affinity of F11 for HA proteins. …”
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Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis
Published 2022“…In summary, we identify LRIs that mark repressed regions of the genome, and these interactions increase across adipogenesis, pinpointing developmental regions that need to be repressed in a cell-type specific way for adipogenesis to proceed.…”
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