Image 1_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien... by Ran Du (552530)

“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”

Data Sheet 1_Differential neuropilin isoform expressions highlight plasticity in macrophages in the heterogenous TME through in-silico profiling.docx by Hyun-Jee Han (20858765)

“…Datasets were processed using established bioinformatics pipelines, including clustering algorithms, to determine cellular heterogeneity and quantify NRP isoform expression within distinct macrophage populations. …”

Data Sheet 2_Differential neuropilin isoform expressions highlight plasticity in macrophages in the heterogenous TME through in-silico profiling.docx by Hyun-Jee Han (20858765)

“…Datasets were processed using established bioinformatics pipelines, including clustering algorithms, to determine cellular heterogeneity and quantify NRP isoform expression within distinct macrophage populations. …”

An Ecological Benchmark of Photo Editing Software: A Comparative Analysis of Local vs. Cloud Workflows by Pierre-Alexis DELAROCHE (22092572)

“…Performance Profiling Algorithms Energy Measurement Methodology # Pseudo-algorithmic representation of measurement protocol def capture_energy_metrics(workflow_type: WorkflowEnum, asset_vector: List[PhotoAsset]) -> EnergyProfile: baseline_power = sample_idle_power_draw(duration=30) with PowerMonitoringContext() as pmc: start_timestamp = rdtsc() # Read time-stamp counter if workflow_type == WorkflowEnum.LOCAL: result = execute_local_pipeline(asset_vector) elif workflow_type == WorkflowEnum.CLOUD: result = execute_cloud_pipeline(asset_vector) end_timestamp = rdtsc() energy_profile = EnergyProfile( duration=cycles_to_seconds(end_timestamp - start_timestamp), peak_power=pmc.get_peak_consumption(), average_power=pmc.get_mean_consumption(), total_energy=integrate_power_curve(pmc.get_power_trace()) ) return energy_profile Statistical Analysis Framework Our analytical pipeline employs advanced statistical methodologies including: Variance Decomposition: ANOVA with nested factors for hardware configuration effects Regression Analysis: Generalized Linear Models (GLM) with log-link functions for energy modeling Temporal Analysis: Fourier transform-based frequency domain analysis of power consumption patterns Cluster Analysis: K-means clustering with Euclidean distance metrics for workflow classification Data Validation and Quality Assurance Measurement Uncertainty Quantification All energy measurements incorporate systematic and random error propagation analysis: Instrument Precision: ±0.1W for CPU power, ±0.5W for GPU power Temporal Resolution: 1ms sampling with Nyquist frequency considerations Calibration Protocol: NIST-traceable power standards with periodic recalibration Environmental Controls: Temperature-compensated measurements in climate-controlled facility Outlier Detection Algorithms Statistical outliers are identified using the Interquartile Range (IQR) method with Tukey's fence criteria (Q₁ - 1.5×IQR, Q₃ + 1.5×IQR). …”

Data used to drive the Double Layer Carbon Model in the Qinling Mountains. by Huiwen Li (17705280)

“…., 2022a), to estimate the spatiotemporal dynamics of SOC in different soil layers and further evaluate the impacts of different climate response functions on SOC estimates in the Qinling Mountains. …”

ISAURO Cognitive Framework v0.1.1 – Public Research Summary (Under 4-Year Embargo) by Megan DeHerrera (21361439)

“…<p>{</p><p dir="ltr"> "title": "ISAURO Cognitive Framework v0.1.1 – Public Research Summary (Under 4-Year Embargo)",</p><p dir="ltr"> "authors": [</p><p> {</p><p dir="ltr"> "name": "Megan Irene DeHerrera",</p><p dir="ltr"> "affiliation": "Revelación Cognitive Research",</p><p dir="ltr"> "orcid_id": "https://orcid.org/0009-0000-2408-9132"</p><p> }</p><p> ],</p><p dir="ltr"> "description": "The ISAURO Cognitive Framework, developed by Megan Irene DeHerrera under Revelación Cognitive Research, is a modular, culturally-aware AI architecture inspired by the adaptive functions of the human brain. It integrates recursive cognition, logic-based memory routing, and trust-calibrated reasoning across a neuromodular system.…”

Table 5_MMPred: a tool to predict peptide mimicry events in MHC class II recognition.xlsx by Filippo Guerri (17017524)

“…To evaluate MMPred’s ability to produce biologically meaningful insights, we conducted a comprehensive assessment involving i) predicting associations between known HLA class II human autoepitopes and microbial-peptide mimicry, ii) interpreting these predictions within a systems biology framework to identify potential functional links between the predicted autoantigens and pathophysiological pathways related to autoimmune diseases, and iii) analyzing illustrative cases in the context of SARS-CoV-2 infection and autoimmunity. …”

Table 3_MMPred: a tool to predict peptide mimicry events in MHC class II recognition.xlsx by Filippo Guerri (17017524)

“…To evaluate MMPred’s ability to produce biologically meaningful insights, we conducted a comprehensive assessment involving i) predicting associations between known HLA class II human autoepitopes and microbial-peptide mimicry, ii) interpreting these predictions within a systems biology framework to identify potential functional links between the predicted autoantigens and pathophysiological pathways related to autoimmune diseases, and iii) analyzing illustrative cases in the context of SARS-CoV-2 infection and autoimmunity. …”

Table 6_MMPred: a tool to predict peptide mimicry events in MHC class II recognition.xlsx by Filippo Guerri (17017524)

“…To evaluate MMPred’s ability to produce biologically meaningful insights, we conducted a comprehensive assessment involving i) predicting associations between known HLA class II human autoepitopes and microbial-peptide mimicry, ii) interpreting these predictions within a systems biology framework to identify potential functional links between the predicted autoantigens and pathophysiological pathways related to autoimmune diseases, and iii) analyzing illustrative cases in the context of SARS-CoV-2 infection and autoimmunity. …”

Table 2_MMPred: a tool to predict peptide mimicry events in MHC class II recognition.xlsx by Filippo Guerri (17017524)

“…To evaluate MMPred’s ability to produce biologically meaningful insights, we conducted a comprehensive assessment involving i) predicting associations between known HLA class II human autoepitopes and microbial-peptide mimicry, ii) interpreting these predictions within a systems biology framework to identify potential functional links between the predicted autoantigens and pathophysiological pathways related to autoimmune diseases, and iii) analyzing illustrative cases in the context of SARS-CoV-2 infection and autoimmunity. …”

Table 4_MMPred: a tool to predict peptide mimicry events in MHC class II recognition.xlsx by Filippo Guerri (17017524)

“…To evaluate MMPred’s ability to produce biologically meaningful insights, we conducted a comprehensive assessment involving i) predicting associations between known HLA class II human autoepitopes and microbial-peptide mimicry, ii) interpreting these predictions within a systems biology framework to identify potential functional links between the predicted autoantigens and pathophysiological pathways related to autoimmune diseases, and iii) analyzing illustrative cases in the context of SARS-CoV-2 infection and autoimmunity. …”

Table 7_MMPred: a tool to predict peptide mimicry events in MHC class II recognition.xlsx by Filippo Guerri (17017524)

“…To evaluate MMPred’s ability to produce biologically meaningful insights, we conducted a comprehensive assessment involving i) predicting associations between known HLA class II human autoepitopes and microbial-peptide mimicry, ii) interpreting these predictions within a systems biology framework to identify potential functional links between the predicted autoantigens and pathophysiological pathways related to autoimmune diseases, and iii) analyzing illustrative cases in the context of SARS-CoV-2 infection and autoimmunity. …”

Table 1_MMPred: a tool to predict peptide mimicry events in MHC class II recognition.xlsx by Filippo Guerri (17017524)

“…To evaluate MMPred’s ability to produce biologically meaningful insights, we conducted a comprehensive assessment involving i) predicting associations between known HLA class II human autoepitopes and microbial-peptide mimicry, ii) interpreting these predictions within a systems biology framework to identify potential functional links between the predicted autoantigens and pathophysiological pathways related to autoimmune diseases, and iii) analyzing illustrative cases in the context of SARS-CoV-2 infection and autoimmunity. …”

Table 8_MMPred: a tool to predict peptide mimicry events in MHC class II recognition.xlsx by Filippo Guerri (17017524)

“…To evaluate MMPred’s ability to produce biologically meaningful insights, we conducted a comprehensive assessment involving i) predicting associations between known HLA class II human autoepitopes and microbial-peptide mimicry, ii) interpreting these predictions within a systems biology framework to identify potential functional links between the predicted autoantigens and pathophysiological pathways related to autoimmune diseases, and iii) analyzing illustrative cases in the context of SARS-CoV-2 infection and autoimmunity. …”

<b>Figures for Protein-Protein interaction (PPI) network of differentially acetylated proteins</b><b> </b><b>by Aspirin during differentiation of THP-1 cell towards macrophage</b> by Zi-Hui Ma (14118552)

“…The protein-protein interaction (PPI) networks were generated using STRING (H. sapiens; confidence score > 0.7) and visualized in Cytoscape 3.2.1. to elucidate how Aspirin-driven acetylated proteins functionally coordinate within cellular systems. The PPI network was further analyzed to identify densely interconnected functional clusters/modules using topological clustering algorithms. …”

<b>Protein-Protein interaction (PPI) network of differentially acetylated proteins</b><b> by Aspirin during differentiation of THP-1 cell towards macrophage</b> by Li Xing (21105170)

“…The protein-protein interaction (PPI) networks were generated using STRING (H. sapiens; confidence score > 0.7) and visualized in Cytoscape 3.2.1. to elucidate how Aspirin-driven acetylated proteins functionally coordinate within cellular systems. The PPI network was further analyzed to identify densely interconnected functional clusters/modules using topological clustering algorithms. …”

Data Sheet 1_Deep learning in microbiome analysis: a comprehensive review of neural network models.pdf by Piotr Przymus (10165658)

“…These computational techniques have become essential for addressing the inherent complexity and high-dimensionality of microbiome data, which consist of different types of omics datasets. Deep learning algorithms have shown remarkable capabilities in pattern recognition, feature extraction, and predictive modeling, enabling researchers to uncover hidden relationships within microbial ecosystems. …”

Data Sheet 2_Deep learning in microbiome analysis: a comprehensive review of neural network models.pdf by Piotr Przymus (10165658)

“…These computational techniques have become essential for addressing the inherent complexity and high-dimensionality of microbiome data, which consist of different types of omics datasets. Deep learning algorithms have shown remarkable capabilities in pattern recognition, feature extraction, and predictive modeling, enabling researchers to uncover hidden relationships within microbial ecosystems. …”

Leadership at the Borders: Reimagining Organizational Development Amid Disrupted Context by Nawaf Al-Ghanem (17925863)

“…Digital infrastructures expand the capacity for cross-border collaboration yet expose organizations to vulnerabilities in cybersecurity, data ethics, and algorithmic inequality. Meanwhile, leadership within multicultural and transnational environments requires navigation across cultural and normative frontiers, demanding a shift from control to coordination, from authority to adaptability, and from hierarchy to networked influence.…”

Image 2_Spatial transcriptomic analysis of 4NQO-induced tongue cancer revealed cellular lineage diversity and evolutionary trajectory.tif by Feng Liu (72874)

“…</p>Methods<p>We leveraged artificial intelligence (AI) algorithms and spatial transcriptomic sequencing to meticulously characterize the spatial and temporal evolution of 4-nitroquinoline-1-oxide (4NQO)-induced tongue carcinogenesis and intratumor heterogeneity.…”