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721
Table 1_Identification and validation of immune and diagnostic biomarkers for interstitial cystitis/painful bladder syndrome by integrating bioinformatics and machine-learning.docx
Published 2025“…Hub genes in IC/BPS patients were identified through the application of three distinct machine-learning algorithms. Additionally, the inflammatory status and immune landscape of IC/BPS patients were evaluated using the ssGSEA algorithm. …”
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722
Data Sheet 1_Identification of key biomarkers related to fibrocartilage chondrocytes for osteoarthritis based on bulk, single-cell transcriptomic data.docx
Published 2024“…Microarray data were integrated to identify differentially expressed genes (DEGs). We conducted functional-enrichment analyses, including Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO), and used weighted gene co-expression network analysis (WGCNA) and the least absolute shrinkage and selection operator (LASSO) algorithm to select biomarkers. …”
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723
Data Sheet 2_Identification of key biomarkers related to fibrocartilage chondrocytes for osteoarthritis based on bulk, single-cell transcriptomic data.csv
Published 2024“…Microarray data were integrated to identify differentially expressed genes (DEGs). We conducted functional-enrichment analyses, including Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO), and used weighted gene co-expression network analysis (WGCNA) and the least absolute shrinkage and selection operator (LASSO) algorithm to select biomarkers. …”
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724
Table 1_A novel prognostic signature identifies MFAP4 as a tumor suppressor linking the tumor microenvironment to PI3K/AKT signaling in triple-negative breast cancer.docx
Published 2025“…The model’s association with TME characteristics was assessed using ESTIMATE algorithm and immune infiltration analyses. The biological functions of the key gene, Microfibril Associated Protein 4 (MFAP4), were investigated in vitro via proliferation and migration assays. …”
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725
Table 2_A novel prognostic signature identifies MFAP4 as a tumor suppressor linking the tumor microenvironment to PI3K/AKT signaling in triple-negative breast cancer.xlsx
Published 2025“…The model’s association with TME characteristics was assessed using ESTIMATE algorithm and immune infiltration analyses. The biological functions of the key gene, Microfibril Associated Protein 4 (MFAP4), were investigated in vitro via proliferation and migration assays. …”
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726
Data Sheet 1_A novel prognostic signature identifies MFAP4 as a tumor suppressor linking the tumor microenvironment to PI3K/AKT signaling in triple-negative breast cancer.pdf
Published 2025“…The model’s association with TME characteristics was assessed using ESTIMATE algorithm and immune infiltration analyses. The biological functions of the key gene, Microfibril Associated Protein 4 (MFAP4), were investigated in vitro via proliferation and migration assays. …”
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727
Table 1_The analysis of gene co-expression network and immune infiltration revealed biomarkers between triple-negative and non-triple negative breast cancer.xlsx
Published 2025“…CIBERSORT analysis was used to characterize the composition of immune cells within complex tissues based on gene expression data, typically derived from bulk RNA sequencing or microarray datasets. …”
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728
Image 1_The analysis of gene co-expression network and immune infiltration revealed biomarkers between triple-negative and non-triple negative breast cancer.tif
Published 2025“…CIBERSORT analysis was used to characterize the composition of immune cells within complex tissues based on gene expression data, typically derived from bulk RNA sequencing or microarray datasets. …”
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729
Image 3_The analysis of gene co-expression network and immune infiltration revealed biomarkers between triple-negative and non-triple negative breast cancer.tif
Published 2025“…CIBERSORT analysis was used to characterize the composition of immune cells within complex tissues based on gene expression data, typically derived from bulk RNA sequencing or microarray datasets. …”
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730
Image 2_The analysis of gene co-expression network and immune infiltration revealed biomarkers between triple-negative and non-triple negative breast cancer.tif
Published 2025“…CIBERSORT analysis was used to characterize the composition of immune cells within complex tissues based on gene expression data, typically derived from bulk RNA sequencing or microarray datasets. …”
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731
Table 2_The analysis of gene co-expression network and immune infiltration revealed biomarkers between triple-negative and non-triple negative breast cancer.xlsx
Published 2025“…CIBERSORT analysis was used to characterize the composition of immune cells within complex tissues based on gene expression data, typically derived from bulk RNA sequencing or microarray datasets. …”
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732
Table 3_The analysis of gene co-expression network and immune infiltration revealed biomarkers between triple-negative and non-triple negative breast cancer.xlsx
Published 2025“…CIBERSORT analysis was used to characterize the composition of immune cells within complex tissues based on gene expression data, typically derived from bulk RNA sequencing or microarray datasets. …”
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733
Image 4_The analysis of gene co-expression network and immune infiltration revealed biomarkers between triple-negative and non-triple negative breast cancer.tif
Published 2025“…CIBERSORT analysis was used to characterize the composition of immune cells within complex tissues based on gene expression data, typically derived from bulk RNA sequencing or microarray datasets. …”
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734
Image 1_Targeting a distinct binding pocket in the pregnane X receptor with natural agonist TRLW-2 ameliorates murine ulcerative colitis.tif
Published 2025“…</p>Methods<p>A distinct binding pocket (Pocket 1–5) within the PXR ligand-binding domain was identified using a multi-algorithm computational approach (SiteMap, Fpocket, Prank, CASTpFold). …”
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735
Image 2_Targeting a distinct binding pocket in the pregnane X receptor with natural agonist TRLW-2 ameliorates murine ulcerative colitis.tif
Published 2025“…</p>Methods<p>A distinct binding pocket (Pocket 1–5) within the PXR ligand-binding domain was identified using a multi-algorithm computational approach (SiteMap, Fpocket, Prank, CASTpFold). …”
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736
Image 3_Targeting a distinct binding pocket in the pregnane X receptor with natural agonist TRLW-2 ameliorates murine ulcerative colitis.tif
Published 2025“…</p>Methods<p>A distinct binding pocket (Pocket 1–5) within the PXR ligand-binding domain was identified using a multi-algorithm computational approach (SiteMap, Fpocket, Prank, CASTpFold). …”
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737
Image 4_Targeting a distinct binding pocket in the pregnane X receptor with natural agonist TRLW-2 ameliorates murine ulcerative colitis.tif
Published 2025“…</p>Methods<p>A distinct binding pocket (Pocket 1–5) within the PXR ligand-binding domain was identified using a multi-algorithm computational approach (SiteMap, Fpocket, Prank, CASTpFold). …”
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738
Additional data for the polyanion sodium cathode materials dataset
Published 2024“…All simulations are executed within the canonical (NVT) ensemble and a sample frequency was set to 1fs.…”
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739
Data Sheet 1_TGM2 regulated by transcription factor NR3C1 drives p38 MAPK-mediated tumor progression and immune evasion in lung squamous cell carcinoma.zip
Published 2025“…Key genes were screened via random forest algorithm. Functional validation was performed in NCI-H520 and SK-MES-1 cell lines. …”
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740
Supporting data for "Machine learning based prognosis prediction of intracerebral hemorrhage outcome".
Published 2025“…The resulting prognosis prediction ML model, based on Random Forest algorithm, achieved an overall accuracy of 0.81, with AUROCs of 0.93, 0.84 and 0.95 for good, poor, and death outcomes, respectively. …”