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Data_Sheet_1_Combining Physiology-Based Modeling and Evolutionary Algorithms for Personalized, Noninvasive Cardiovascular Assessment Based on Electrocardiography and Ballistocardio...
Published 2022“…<p>Purpose: This study proposes a novel approach to obtain personalized estimates of cardiovascular parameters by combining (i) electrocardiography and ballistocardiography for noninvasive cardiovascular monitoring, (ii) a physiology-based mathematical model for predicting personalized cardiovascular variables, and (iii) an evolutionary algorithm (EA) for searching optimal model parameters.…”
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Algorithmic assessment reveals functional implications of GABRD gene variants linked to idiopathic generalized epilepsy
Published 2024“…</p> <p>The study employs a combination of in silico algorithms to analyze 82 variants of unknown clinical significance of GABRD gene sourced from the ClinVar database. …”
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A hybrid algorithm based on improved threshold function and wavelet transform.
Published 2024“…<p>A hybrid algorithm based on improved threshold function and wavelet transform.…”
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The PS of ten comparative algorithms on the MMF14a Test Function.
Published 2025“…<p>The PS of ten comparative algorithms on the MMF14a Test Function.</p>…”
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The Blood–Brain Barrier (BBB) Score
Published 2019“…Understanding the BBB interaction with drug molecules based on physicochemical property space can guide effective and efficient drug design. An algorithm, designated “BBB Score”, composed of stepwise and polynomial piecewise functions, is herein proposed for predicting BBB penetration based on five physicochemical descriptors: number of aromatic rings, heavy atoms, MWHBN (a descriptor comprising molecular weight, hydrogen bond donor, and hydrogen bond acceptors), topological polar surface area, and pKa. …”
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The Blood–Brain Barrier (BBB) Score
Published 2019“…Understanding the BBB interaction with drug molecules based on physicochemical property space can guide effective and efficient drug design. An algorithm, designated “BBB Score”, composed of stepwise and polynomial piecewise functions, is herein proposed for predicting BBB penetration based on five physicochemical descriptors: number of aromatic rings, heavy atoms, MWHBN (a descriptor comprising molecular weight, hydrogen bond donor, and hydrogen bond acceptors), topological polar surface area, and pKa. …”
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The Blood–Brain Barrier (BBB) Score
Published 2019“…Understanding the BBB interaction with drug molecules based on physicochemical property space can guide effective and efficient drug design. An algorithm, designated “BBB Score”, composed of stepwise and polynomial piecewise functions, is herein proposed for predicting BBB penetration based on five physicochemical descriptors: number of aromatic rings, heavy atoms, MWHBN (a descriptor comprising molecular weight, hydrogen bond donor, and hydrogen bond acceptors), topological polar surface area, and pKa. …”
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Image_1_Multimodal Evaluation of Neurovascular Functionality in Early Parkinson's Disease.TIFF
Published 2020“…<p>Parkinson's disease (PD) is a multisystem neurological condition affecting different neurotransmitter pathways characterized by aberrant functional connectivity (FC) and perfusion alteration. …”
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Table_1_Multimodal Evaluation of Neurovascular Functionality in Early Parkinson's Disease.DOCX
Published 2020“…<p>Parkinson's disease (PD) is a multisystem neurological condition affecting different neurotransmitter pathways characterized by aberrant functional connectivity (FC) and perfusion alteration. …”
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Flowchart of proposed fitness function algorithm.
Published 2025“…The mathematical model was transformed into a fitness function and a solution was provided with the Tabu Search Algorithm and Simulated Annealing. …”
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Function graph and algorithm iterative graph.
Published 2024“…According to the encouraging research results in this paper, the IERWHO algorithm proposed has a place in the field of optimization.…”
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