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MOMA compared to MFA-derived estimates, carbon yield efficiencies and CBA co-factor profile comparison across unconstrained, manually curated and experimentally constrained solutio...
Published 2020“…MOMA ranges were estimated using the wild type solution as a reference and sequentially implementing the single-gene knockouts studied by Long et al. (2019) [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008125#pcbi.1008125.ref046" target="_blank">46</a>], with biomass formation as the objective function. MFA ranges were extracted from a pre-existing dataset (Long et al., 2019), using a Python algorithm to select the minimal and maximal flux ranges.…”