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algorithm protein » algorithm within (Expand Search), algorithm pre (Expand Search)
algorithm python » algorithm within (Expand Search), algorithms within (Expand Search), algorithm both (Expand Search)
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441
Presentation 1_Viral replication modulated by hallmark conformational ensembles: how AlphaFold-predicted features of RdRp folding dynamics combined with intrinsic disorder-mediated...
Published 2025“…<p>The functions of RNA-dependent RNA polymerases (RdRps) in RNA viruses are demonstrably modulated by native substrates of dynamic and interconvertible conformational ensembles. …”
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442
Data Sheet 2_Viral replication modulated by hallmark conformational ensembles: how AlphaFold-predicted features of RdRp folding dynamics combined with intrinsic disorder-mediated f...
Published 2025“…<p>The functions of RNA-dependent RNA polymerases (RdRps) in RNA viruses are demonstrably modulated by native substrates of dynamic and interconvertible conformational ensembles. …”
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443
Data Sheet 1_Viral replication modulated by hallmark conformational ensembles: how AlphaFold-predicted features of RdRp folding dynamics combined with intrinsic disorder-mediated f...
Published 2025“…<p>The functions of RNA-dependent RNA polymerases (RdRps) in RNA viruses are demonstrably modulated by native substrates of dynamic and interconvertible conformational ensembles. …”
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444
Data Sheet 3_Viral replication modulated by hallmark conformational ensembles: how AlphaFold-predicted features of RdRp folding dynamics combined with intrinsic disorder-mediated f...
Published 2025“…<p>The functions of RNA-dependent RNA polymerases (RdRps) in RNA viruses are demonstrably modulated by native substrates of dynamic and interconvertible conformational ensembles. …”
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445
The information of datasets used in this study.
Published 2024“…Both machine learning algorithms identified Ribosomal Protein L22-like 1 (RPL22L1) and Lymphocyte Antigen 96 (LY96) as potential diagnostic markers for PsA and RA. …”
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446
The workflow of the present study.
Published 2024“…Both machine learning algorithms identified Ribosomal Protein L22-like 1 (RPL22L1) and Lymphocyte Antigen 96 (LY96) as potential diagnostic markers for PsA and RA. …”
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447
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448
Overview of the research process.
Published 2025“…We used the automated docking suite GOLD v5.5 with the genetic algorithm to simulate molecular docking and predict the protein-ligand binding modes, and the ChemPLP empirical scoring function to estimate the binding affinities of 2,115 FDA-approved drugs to the human Ca<sub>v</sub>3.1 channel. …”
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449
The overall framework of this study.
Published 2025“…PANoptosis score in SCI samples was significantly higher than in HC samples. Additionally, a protein-protein interaction (PPI) network was established to identify hub genes, and 8 machine learning algorithms were used to narrowed down hub genes. …”
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450
PANoptosis related genes.
Published 2025“…PANoptosis score in SCI samples was significantly higher than in HC samples. Additionally, a protein-protein interaction (PPI) network was established to identify hub genes, and 8 machine learning algorithms were used to narrowed down hub genes. …”
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451
Primer sequences of <i>Bm</i>x and β-actin.
Published 2025“…PANoptosis score in SCI samples was significantly higher than in HC samples. Additionally, a protein-protein interaction (PPI) network was established to identify hub genes, and 8 machine learning algorithms were used to narrowed down hub genes. …”
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452
Hippocampal and cortical activity reflect early hyperexcitability in an Alzheimer's mouse model
Published 2025“…</p><p dir="ltr">All data are available upon request. The standalone Python implementation of the fE/I algorithm is available under a CC-BY-NC-SA license at <a href="https://github.com/arthur-ervin/crosci" target="_blank">https://github.com/arthur-ervin/crosci</a>. …”
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453
Dataset for ACPs.
Published 2025“…The framework leverages the ESMC protein language model to extract comprehensive sequence features and employs a novel adaptive algorithm, ANBS, to mitigate class imbalance at the decision boundary. …”
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454
Framework of HyperACP.
Published 2025“…The framework leverages the ESMC protein language model to extract comprehensive sequence features and employs a novel adaptive algorithm, ANBS, to mitigate class imbalance at the decision boundary. …”
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455
Models of the ESM series and their parameters.
Published 2025“…The framework leverages the ESMC protein language model to extract comprehensive sequence features and employs a novel adaptive algorithm, ANBS, to mitigate class imbalance at the decision boundary. …”
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456
Performance of ensemble models on ACP135.
Published 2025“…The framework leverages the ESMC protein language model to extract comprehensive sequence features and employs a novel adaptive algorithm, ANBS, to mitigate class imbalance at the decision boundary. …”
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457
Performance of ensemble models on ACP 99.
Published 2025“…The framework leverages the ESMC protein language model to extract comprehensive sequence features and employs a novel adaptive algorithm, ANBS, to mitigate class imbalance at the decision boundary. …”
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458
Pocket clustering statistics.
Published 2025“…Our study revealed a sub-linear scaling law of the number of unique binding sites relative to the number of unique protein structures per species. Thus, as proteomes increased in size during evolution and therefore potentially diversified, the number of distinct binding sites, reflecting potentially diversifying functions, grew less than proportionally. …”
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