Image3_A young child formula supplemented with a synbiotic mixture of scGOS/lcFOS and Bifidobacterium breve M-16V improves the gut microbiota and iron status in healthy toddlers.pd... حسب Charmaine Chew (9739238)

"…PICRUSt, a predictive functionality algorithm based on 16S ribosomal gene sequencing, was used to correlate potential microbial functions with iron status measurements. …"

Data Sheet 1_Comprehensive analyses of telomerase component DKC1 and its association with clinical, molecular and immune landscapes in uterine corpus endometrial carcinoma.pdf حسب Chenxi Sun (11946467)

"…For the TCGA cohort, DKC1 mRNA and protein levels increased significantly in tumors compared with that in NTs. …"

Table1_Comprehensive pan-cancer analysis and experiments revealed R3HDM1 as a novel predictive biomarker for prognosis and immune therapy response.DOCX حسب Jiawei Liu (553742)

"…Background<p>R3HDM1, an RNA binding protein with one R3H domain, remains uncharacterized in terms of its association with tumor progression, malignant cell regulation, and the tumor immune microenvironment. …"

Table 1_Bioinformatic analysis, clinical implications and experimental validation of ferroptosis-related feature gene in IgA nephropathy: focus on DUSP1.docx حسب Tingting Liu (267387)

"…GSEA further identified DUSP1’s functional enrichment in critical signaling networks, particularly mitogen-activated protein kinase (MAPK) cascades, ERBB receptor tyrosine kinase pathways, and Janus kinase-signal transducer (JAK–STAT) transduction mechanisms. …"

Table 2_Bioinformatic analysis, clinical implications and experimental validation of ferroptosis-related feature gene in IgA nephropathy: focus on DUSP1.xlsx حسب Tingting Liu (267387)

"…GSEA further identified DUSP1’s functional enrichment in critical signaling networks, particularly mitogen-activated protein kinase (MAPK) cascades, ERBB receptor tyrosine kinase pathways, and Janus kinase-signal transducer (JAK–STAT) transduction mechanisms. …"

Image 1_Mitochondrial insights: key biomarkers and potential treatments for diabetic nephropathy and sarcopenia.tif حسب Yi Wei Chen (21684728)

"…Utilizing four machine learning algorithms (LASSO, SVM, XGBoost, RF), we pinpointed three mitochondrial hub genes. …"

Table 1_A machine learning-based predictive model for the occurrence of lower extremity deep vein thrombosis after laparoscopic surgery in abdominal surgery.xlsx حسب Su-Zhen Yang (21448877)

"…Twenty machine learning algorithms were evaluated, and the top five algorithms were used to build the final model by stacking.…"

Table 2_A machine learning-based predictive model for the occurrence of lower extremity deep vein thrombosis after laparoscopic surgery in abdominal surgery.xlsx حسب Su-Zhen Yang (21448877)

"…Twenty machine learning algorithms were evaluated, and the top five algorithms were used to build the final model by stacking.…"

Data Sheet 1_Exploring the molecular mechanisms of phthalates in the comorbidity of preeclampsia and depression by integrating multiple datasets.zip حسب Xinpeng Tian (646275)

"…Protein–protein interaction integration and functional enrichment analyses were then applied to identify shared regulatory pathways. …"

Data Sheet 2_Robust reference gene selection in Norway spruce: essential for real-time quantitative PCR across different tissue, stress and developmental conditions.docx حسب Vivek Vikram Singh (16010390)

"…Our results highlight ubiquitin-protein ligase (SP1), conserved oligomeric Golgi complex (COG7), and tubby-like F-box protein (TULP6) as the most stable reference genes, while succinate dehydrogenase (SDH5) and heat shock protein 90 (HSP90) were the least stable under various experimental conditions. …"

Data Sheet 7_Robust reference gene selection in Norway spruce: essential for real-time quantitative PCR across different tissue, stress and developmental conditions.docx حسب Vivek Vikram Singh (16010390)

"…Our results highlight ubiquitin-protein ligase (SP1), conserved oligomeric Golgi complex (COG7), and tubby-like F-box protein (TULP6) as the most stable reference genes, while succinate dehydrogenase (SDH5) and heat shock protein 90 (HSP90) were the least stable under various experimental conditions. …"

Data Sheet 5_Robust reference gene selection in Norway spruce: essential for real-time quantitative PCR across different tissue, stress and developmental conditions.docx حسب Vivek Vikram Singh (16010390)

"…Our results highlight ubiquitin-protein ligase (SP1), conserved oligomeric Golgi complex (COG7), and tubby-like F-box protein (TULP6) as the most stable reference genes, while succinate dehydrogenase (SDH5) and heat shock protein 90 (HSP90) were the least stable under various experimental conditions. …"

Data Sheet 6_Robust reference gene selection in Norway spruce: essential for real-time quantitative PCR across different tissue, stress and developmental conditions.docx حسب Vivek Vikram Singh (16010390)

"…Our results highlight ubiquitin-protein ligase (SP1), conserved oligomeric Golgi complex (COG7), and tubby-like F-box protein (TULP6) as the most stable reference genes, while succinate dehydrogenase (SDH5) and heat shock protein 90 (HSP90) were the least stable under various experimental conditions. …"

Data Sheet 3_Robust reference gene selection in Norway spruce: essential for real-time quantitative PCR across different tissue, stress and developmental conditions.docx حسب Vivek Vikram Singh (16010390)

"…Our results highlight ubiquitin-protein ligase (SP1), conserved oligomeric Golgi complex (COG7), and tubby-like F-box protein (TULP6) as the most stable reference genes, while succinate dehydrogenase (SDH5) and heat shock protein 90 (HSP90) were the least stable under various experimental conditions. …"

Data Sheet 1_Robust reference gene selection in Norway spruce: essential for real-time quantitative PCR across different tissue, stress and developmental conditions.docx حسب Vivek Vikram Singh (16010390)

"…Our results highlight ubiquitin-protein ligase (SP1), conserved oligomeric Golgi complex (COG7), and tubby-like F-box protein (TULP6) as the most stable reference genes, while succinate dehydrogenase (SDH5) and heat shock protein 90 (HSP90) were the least stable under various experimental conditions. …"

Data Sheet 4_Robust reference gene selection in Norway spruce: essential for real-time quantitative PCR across different tissue, stress and developmental conditions.xlsx حسب Vivek Vikram Singh (16010390)

"…Our results highlight ubiquitin-protein ligase (SP1), conserved oligomeric Golgi complex (COG7), and tubby-like F-box protein (TULP6) as the most stable reference genes, while succinate dehydrogenase (SDH5) and heat shock protein 90 (HSP90) were the least stable under various experimental conditions. …"

Supplementary file 1_Plasma FGF2 and YAP1 as novel biomarkers for MCI in the elderly: analysis via bioinformatics and clinical study.docx حسب Yejing Zhao (22123588)

"…Functional enrichment analysis showed that fibroblast growth factor 2(FGF2) and yes-associated protein 1(YAP1) protein levels were highly expressed in AD samples, indicating their potential regulatory roles in AD. …"

Image2_Identification of novel biomarkers, shared molecular signatures and immune cell infiltration in heart and kidney failure by transcriptomics.tif حسب Qingqing Long (845156)

"…A protein-protein interaction (PPI) network was constructed, and machine learning algorithms, including Random Forest (RF), Support Vector Machine-Recursive Feature Elimination (SVM-RFE), and Least Absolute Shrinkage and Selection Operator (LASSO), were used to identify key signature genes. …"

Image1_Identification of novel biomarkers, shared molecular signatures and immune cell infiltration in heart and kidney failure by transcriptomics.tif حسب Qingqing Long (845156)

"…A protein-protein interaction (PPI) network was constructed, and machine learning algorithms, including Random Forest (RF), Support Vector Machine-Recursive Feature Elimination (SVM-RFE), and Least Absolute Shrinkage and Selection Operator (LASSO), were used to identify key signature genes. …"

Data Sheet 1_Genetic variants and molecular profiling of 46,XY gonadal dysgenesis using whole-exome sequencing.docx حسب Ning Zhang (23771)

"…These variant sites are conserved among species and were predicted to be damaging according to functional algorithms and protein analyses. Additionally, 71.4% of the GATA4 amino acid changes in 46,XY GD were located in or close to the N-terminal zinc finger (N-ZF) domain. …"