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1341
Image 5_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1342
Image 10_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patie...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1343
Image 8_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1344
Table 4_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1345
Image 11_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patie...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1346
Image 2_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1347
Image 9_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1348
Table 2_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1349
Table 3_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1350
Table 1_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1351
Image 12_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patie...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1352
Image 3_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1353
Image 6_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1354
Image 7_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1355
Image 1_Immune intrinsic escape signature stratifies prognosis, characterizes the tumor immune microenvironment, and identifies tumorigenic PPP1R8 in glioblastoma multiforme patien...
Published 2025“…TIME analysis was carried out using multiple deconvolution algorithms. Additionally, functional assays including CCK8, cell cycle, and apoptosis assays were conducted on PPP1R8-silenced U251 cells using CRISPR/Cas9 technology</p>Results<p>Thirty-six IERGs were associated with GBM outcomes, with 20 linked to poor survival and 16 to better outcomes. …”
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1356
ISAURO Cognitive Framework v0.1.1 – Public Research Summary (Under 4-Year Embargo)
Published 2025“…<p>{</p><p dir="ltr"> "title": "ISAURO Cognitive Framework v0.1.1 – Public Research Summary (Under 4-Year Embargo)",</p><p dir="ltr"> "authors": [</p><p> {</p><p dir="ltr"> "name": "Megan Irene DeHerrera",</p><p dir="ltr"> "affiliation": "Revelación Cognitive Research",</p><p dir="ltr"> "orcid_id": "https://orcid.org/0009-0000-2408-9132"</p><p> }</p><p> ],</p><p dir="ltr"> "description": "The ISAURO Cognitive Framework, developed by Megan Irene DeHerrera under Revelación Cognitive Research, is a modular, culturally-aware AI architecture inspired by the adaptive functions of the human brain. It integrates recursive cognition, logic-based memory routing, and trust-calibrated reasoning across a neuromodular system.…”
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1357
Expression vs genomics for predicting dependencies
Published 2024“…If you are interested in trying machine learning, the files Features.hdf5 and Target.hdf5 contain the data munged in a convenient form for standard supervised machine learning algorithms.</p><p dir="ltr"><br></p><p dir="ltr">Some large files are in the binary format hdf5 for efficiency in space and read-in. …”
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1358
An Ecological Benchmark of Photo Editing Software: A Comparative Analysis of Local vs. Cloud Workflows
Published 2025“…Performance Profiling Algorithms Energy Measurement Methodology # Pseudo-algorithmic representation of measurement protocol def capture_energy_metrics(workflow_type: WorkflowEnum, asset_vector: List[PhotoAsset]) -> EnergyProfile: baseline_power = sample_idle_power_draw(duration=30) with PowerMonitoringContext() as pmc: start_timestamp = rdtsc() # Read time-stamp counter if workflow_type == WorkflowEnum.LOCAL: result = execute_local_pipeline(asset_vector) elif workflow_type == WorkflowEnum.CLOUD: result = execute_cloud_pipeline(asset_vector) end_timestamp = rdtsc() energy_profile = EnergyProfile( duration=cycles_to_seconds(end_timestamp - start_timestamp), peak_power=pmc.get_peak_consumption(), average_power=pmc.get_mean_consumption(), total_energy=integrate_power_curve(pmc.get_power_trace()) ) return energy_profile Statistical Analysis Framework Our analytical pipeline employs advanced statistical methodologies including: Variance Decomposition: ANOVA with nested factors for hardware configuration effects Regression Analysis: Generalized Linear Models (GLM) with log-link functions for energy modeling Temporal Analysis: Fourier transform-based frequency domain analysis of power consumption patterns Cluster Analysis: K-means clustering with Euclidean distance metrics for workflow classification Data Validation and Quality Assurance Measurement Uncertainty Quantification All energy measurements incorporate systematic and random error propagation analysis: Instrument Precision: ±0.1W for CPU power, ±0.5W for GPU power Temporal Resolution: 1ms sampling with Nyquist frequency considerations Calibration Protocol: NIST-traceable power standards with periodic recalibration Environmental Controls: Temperature-compensated measurements in climate-controlled facility Outlier Detection Algorithms Statistical outliers are identified using the Interquartile Range (IQR) method with Tukey's fence criteria (Q₁ - 1.5×IQR, Q₃ + 1.5×IQR). …”
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1359
Data_Sheet_1_Back-Propagation Learning in Deep Spike-By-Spike Networks.pdf
Published 2019“…What is missing, however, are algorithms for finding weight sets that would optimize the output performances of deep SbS networks with many layers. …”
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1360
Data_Sheet_2_Back-Propagation Learning in Deep Spike-By-Spike Networks.ZIP
Published 2019“…What is missing, however, are algorithms for finding weight sets that would optimize the output performances of deep SbS networks with many layers. …”