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2581
Table 2_Construction and validation of immune prognosis model for lung adenocarcinoma based on machine learning.docx
Published 2025“…Differentially expressed genes and immune-related genes from the IMMPORT database were integrated using WGCNA. …”
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2582
Table 1_Construction and validation of immune prognosis model for lung adenocarcinoma based on machine learning.docx
Published 2025“…Differentially expressed genes and immune-related genes from the IMMPORT database were integrated using WGCNA. …”
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2583
Supplementary file 1_Transcriptomic analysis and machine learning modeling identifies novel biomarkers and genetic characteristics of hypertrophic cardiomyopathy.xlsx
Published 2025“…Computational analysis was performed to compare transcriptomic profiles between normal cardiac tissues from healthy donors and myocardial tissues from HCM patients. …”
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2584
Bioinformatics-based screening and experimental validation of biomarkers for the treatment of connective tissue-associated interstitial lung disease with liquorice and dried ginger...
Published 2025“…</p> <p>Public datasets of Peripheral blood mononuclear cells (PBMCs) from CTD-ILD (n = 4) and connective tissue disease-associated non-Inflammatory lung disease (CTD-NILD) (n = 3) patients were analyzed using differential expression (p.adj < 0.05 & |log2 Fold Change (FC)| > 0.5), protein-protein interaction networks, and cytohubba algorithms (Top5 genes from six algorithms). …”
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2585
Image 5_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.tif
Published 2025“…Candidate prognostic genes identified from malignant epithelial subsets were further used to develop a Pyroptosis-Related Gene Signature (PRGS) through a systematic evaluation of ten machine learning algorithms and their combinations, with subsequent validation across multiple cohorts. …”
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2586
Image 3_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.tif
Published 2025“…Candidate prognostic genes identified from malignant epithelial subsets were further used to develop a Pyroptosis-Related Gene Signature (PRGS) through a systematic evaluation of ten machine learning algorithms and their combinations, with subsequent validation across multiple cohorts. …”
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2587
Table 2_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.xlsx
Published 2025“…Candidate prognostic genes identified from malignant epithelial subsets were further used to develop a Pyroptosis-Related Gene Signature (PRGS) through a systematic evaluation of ten machine learning algorithms and their combinations, with subsequent validation across multiple cohorts. …”
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2588
Image 1_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.tif
Published 2025“…Candidate prognostic genes identified from malignant epithelial subsets were further used to develop a Pyroptosis-Related Gene Signature (PRGS) through a systematic evaluation of ten machine learning algorithms and their combinations, with subsequent validation across multiple cohorts. …”
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2589
Image 4_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.tif
Published 2025“…Candidate prognostic genes identified from malignant epithelial subsets were further used to develop a Pyroptosis-Related Gene Signature (PRGS) through a systematic evaluation of ten machine learning algorithms and their combinations, with subsequent validation across multiple cohorts. …”
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2590
Table 1_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.xlsx
Published 2025“…Candidate prognostic genes identified from malignant epithelial subsets were further used to develop a Pyroptosis-Related Gene Signature (PRGS) through a systematic evaluation of ten machine learning algorithms and their combinations, with subsequent validation across multiple cohorts. …”
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2591
Image 2_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.tif
Published 2025“…Candidate prognostic genes identified from malignant epithelial subsets were further used to develop a Pyroptosis-Related Gene Signature (PRGS) through a systematic evaluation of ten machine learning algorithms and their combinations, with subsequent validation across multiple cohorts. …”
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2592
Image 1_Multi-omics integration analysis based on plasma circulating proteins reveals potential therapeutic targets for ulcerative colitis.pdf
Published 2025“…Three machine learning (ML) algorithms were employed to screen core hub genes from these overlapping genes, followed by the construction and external validation of a diagnostic model. …”
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2593
Data Sheet 1_Multi-omics integration analysis based on plasma circulating proteins reveals potential therapeutic targets for ulcerative colitis.xlsx
Published 2025“…Three machine learning (ML) algorithms were employed to screen core hub genes from these overlapping genes, followed by the construction and external validation of a diagnostic model. …”
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2594
Table 1_Machine learning identifies PYGM as a macrophage polarization–linked metabolic biomarker in rectal cancer prognosis.docx
Published 2025“…</p>Methods<p>We constructed a macrophage polarization gene signature (MPGS) by integrating weighted gene co-expression network analysis (WGCNA) with multiple machine learning algorithms across two independent cohorts: 363 rectal cancer samples from GSE87211 and 177 samples from The Cancer Genome Atlas (TCGA). …”
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2595
Study flowchart.
Published 2025“…Differential expression gene (DEG) analysis was performed on the profiles, followed by further screening using four machine learning algorithms. Concurrently, weighted gene co-expression network analysis (WGCNA) was applied to identify gene modules, and enrichment analysis of WGCNA-derived genes was conducted to explore their biological functions. …”
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2596
The top ten related predicted drug compounds.
Published 2025“…Differential expression gene (DEG) analysis was performed on the profiles, followed by further screening using four machine learning algorithms. Concurrently, weighted gene co-expression network analysis (WGCNA) was applied to identify gene modules, and enrichment analysis of WGCNA-derived genes was conducted to explore their biological functions. …”
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2597
Table 3_Combining WGCNA and machine learning to identify mechanisms and biomarkers of hyperthyroidism and atrial fibrillation.xlsx
Published 2025“…Differential gene analysis was performed using the “limma” package, and overlapping genes shared by both diseases were identified through weighted gene co-expression network analysis (WGCNA), followed by functional enrichment analysis. Machine learning algorithms were also applied to identify key biomarkers. …”
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2598
Table 4_Combining WGCNA and machine learning to identify mechanisms and biomarkers of hyperthyroidism and atrial fibrillation.docx
Published 2025“…Differential gene analysis was performed using the “limma” package, and overlapping genes shared by both diseases were identified through weighted gene co-expression network analysis (WGCNA), followed by functional enrichment analysis. Machine learning algorithms were also applied to identify key biomarkers. …”
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2599
Table 5_Combining WGCNA and machine learning to identify mechanisms and biomarkers of hyperthyroidism and atrial fibrillation.docx
Published 2025“…Differential gene analysis was performed using the “limma” package, and overlapping genes shared by both diseases were identified through weighted gene co-expression network analysis (WGCNA), followed by functional enrichment analysis. Machine learning algorithms were also applied to identify key biomarkers. …”
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2600
Table 1_Combining WGCNA and machine learning to identify mechanisms and biomarkers of hyperthyroidism and atrial fibrillation.xlsx
Published 2025“…Differential gene analysis was performed using the “limma” package, and overlapping genes shared by both diseases were identified through weighted gene co-expression network analysis (WGCNA), followed by functional enrichment analysis. Machine learning algorithms were also applied to identify key biomarkers. …”