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algorithm python » algorithm within (Expand Search), algorithms within (Expand Search), algorithm both (Expand Search)
python function » protein function (Expand Search)
algorithm b » algorithm _ (Expand Search), algorithms _ (Expand Search)
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1261
Image 4_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.tif
Published 2025“…Drug sensitivity analyses revealed distinct therapeutic vulnerabilities between subgroups. Functional assays confirmed that MAP1B promotes proliferation, migration, and invasion in GBM cells, reinforcing its oncogenic role.…”
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1262
Table 1_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.xlsx
Published 2025“…Drug sensitivity analyses revealed distinct therapeutic vulnerabilities between subgroups. Functional assays confirmed that MAP1B promotes proliferation, migration, and invasion in GBM cells, reinforcing its oncogenic role.…”
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1263
Image 2_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.tif
Published 2025“…Drug sensitivity analyses revealed distinct therapeutic vulnerabilities between subgroups. Functional assays confirmed that MAP1B promotes proliferation, migration, and invasion in GBM cells, reinforcing its oncogenic role.…”
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1264
Construction of a novel radioresistance-related signature for prediction of prognosis, immune microenvironment and anti-tumour drug sensitivity in non-small cell lung cancer
Published 2025“…</p> <p>Ninety-nine RRRGs were screened by intersecting the results of DEGs and WGCNA, then 11 hub RRRGs associated with survival were identified using machine learning algorithms (LASSO and RSF). Subsequently, an eight-gene (<i>APOBEC3B, DOCK4, IER5L, LBH, LY6K, RERG, RMDN2</i> and <i>TSPAN2</i>) risk score model was established and demonstrated to be an independent prognostic factor in NSCLC on the basis of Cox regression analysis. …”
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1265
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1266
Turkish_native_goat_genotypes
Published 2025“…An ensemble feature-importance analysis, evaluated through 10,000 permutations, identified 31 FDR-significant SNPs representing markers consistently associated with MAP status. Functional annotation indicated involvement of immune-related processes such as cytokine–receptor signalling, antigen presentation, glycan-mediated T-cell regulation, and NF-κB–linked inflammatory pathways. …”
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1267
Image 3_SUMOylation-related genes define prognostic subtypes in stomach adenocarcinoma: integrating single-cell analysis and machine learning analyses.tif
Published 2025“…Immune infiltration, pathway enrichment identified key SRGs, and in vitro functional assays were validated.</p>Results<p>Two molecular subtypes (A/B) with distinct SUMOylation patterns, survival outcomes (log-rank p < 0.001), and immune microenvironments were identified. …”
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1268
Image 1_SUMOylation-related genes define prognostic subtypes in stomach adenocarcinoma: integrating single-cell analysis and machine learning analyses.tif
Published 2025“…Immune infiltration, pathway enrichment identified key SRGs, and in vitro functional assays were validated.</p>Results<p>Two molecular subtypes (A/B) with distinct SUMOylation patterns, survival outcomes (log-rank p < 0.001), and immune microenvironments were identified. …”
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1269
Image 2_SUMOylation-related genes define prognostic subtypes in stomach adenocarcinoma: integrating single-cell analysis and machine learning analyses.tif
Published 2025“…Immune infiltration, pathway enrichment identified key SRGs, and in vitro functional assays were validated.</p>Results<p>Two molecular subtypes (A/B) with distinct SUMOylation patterns, survival outcomes (log-rank p < 0.001), and immune microenvironments were identified. …”
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1270
Image 4_SUMOylation-related genes define prognostic subtypes in stomach adenocarcinoma: integrating single-cell analysis and machine learning analyses.tif
Published 2025“…Immune infiltration, pathway enrichment identified key SRGs, and in vitro functional assays were validated.</p>Results<p>Two molecular subtypes (A/B) with distinct SUMOylation patterns, survival outcomes (log-rank p < 0.001), and immune microenvironments were identified. …”
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1271
Image 1_Integrated bioinformatics and molecular docking analysis reveal potential hub genes and targeted therapeutics in sepsis-associated acute lung injury.jpeg
Published 2025“…Hub genes were screened using PPI network construction and three machine learning algorithms, and validated by Western blot. Functional enrichment, immune infiltration, and drug prediction (DSigDB) were performed, followed by molecular docking.…”
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1272
Table 1_Integrated bioinformatics and molecular docking analysis reveal potential hub genes and targeted therapeutics in sepsis-associated acute lung injury.docx
Published 2025“…Hub genes were screened using PPI network construction and three machine learning algorithms, and validated by Western blot. Functional enrichment, immune infiltration, and drug prediction (DSigDB) were performed, followed by molecular docking.…”
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1273
Table 2_Integrated bioinformatics and molecular docking analysis reveal potential hub genes and targeted therapeutics in sepsis-associated acute lung injury.docx
Published 2025“…Hub genes were screened using PPI network construction and three machine learning algorithms, and validated by Western blot. Functional enrichment, immune infiltration, and drug prediction (DSigDB) were performed, followed by molecular docking.…”
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1274
Table 1_Development and validation of a machine-learning-based model for identification of genes associated with sepsis-associated acute kidney injury.docx
Published 2025“…Finally, we used functional enrichment analysis to identify potential therapeutic agents for AKI.…”
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1275
Data Sheet 3_Key gene screening and diagnostic model establishment for acute type a aortic dissection.csv
Published 2025“…</p>Methods<p>Transcriptome datasets from the Gene Expression Omnibus (GEO) database were analyzed using differential expression analysis, weighted gene co-expression network analysis (WGCNA), and machine learning algorithms (SVM, Random Forest, LASSO regression). Functional enrichment and immunoinfiltration analyses were performed to explore biological pathways and immune cell interactions. …”
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1276
Data Sheet 2_Key gene screening and diagnostic model establishment for acute type a aortic dissection.csv
Published 2025“…</p>Methods<p>Transcriptome datasets from the Gene Expression Omnibus (GEO) database were analyzed using differential expression analysis, weighted gene co-expression network analysis (WGCNA), and machine learning algorithms (SVM, Random Forest, LASSO regression). Functional enrichment and immunoinfiltration analyses were performed to explore biological pathways and immune cell interactions. …”
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1277
Table1_“Dictionary of immune responses” reveals the critical role of monocytes and the core target IRF7 in intervertebral disc degeneration.xls
Published 2024“…IREA revealed that monocytes in IDD polarize into an IFN-a1 and IFN-b enriched Mono-a state, potentially intensifying inflammation. …”
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1278
Table 1_Key gene screening and diagnostic model establishment for acute type a aortic dissection.xlsx
Published 2025“…</p>Methods<p>Transcriptome datasets from the Gene Expression Omnibus (GEO) database were analyzed using differential expression analysis, weighted gene co-expression network analysis (WGCNA), and machine learning algorithms (SVM, Random Forest, LASSO regression). Functional enrichment and immunoinfiltration analyses were performed to explore biological pathways and immune cell interactions. …”
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1279
Image2_“Dictionary of immune responses” reveals the critical role of monocytes and the core target IRF7 in intervertebral disc degeneration.jpeg
Published 2024“…IREA revealed that monocytes in IDD polarize into an IFN-a1 and IFN-b enriched Mono-a state, potentially intensifying inflammation. …”
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1280
Data Sheet 4_Key gene screening and diagnostic model establishment for acute type a aortic dissection.csv
Published 2025“…</p>Methods<p>Transcriptome datasets from the Gene Expression Omnibus (GEO) database were analyzed using differential expression analysis, weighted gene co-expression network analysis (WGCNA), and machine learning algorithms (SVM, Random Forest, LASSO regression). Functional enrichment and immunoinfiltration analyses were performed to explore biological pathways and immune cell interactions. …”