Data Sheet 1_Identification of novel molecular subtypes and construction of a prognostic signature via multi-omics analysis and machine learning in lung adenocarcinoma.docx حسب Ke Ma (260231)

"…</p>Results<p>Our analysis revealed that the novel molecular subtypes exhibited differences in prognoses, biological functions, and immune infiltration profiles in LUAD. …"

Image 5_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.tif حسب Liren Fang (22489516)

"…The PRGS, established by StepCox[both]+Ridge modeling, demonstrated robust prognostic stratification and predictive power across independent datasets. …"

Image 3_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.tif حسب Liren Fang (22489516)

"…The PRGS, established by StepCox[both]+Ridge modeling, demonstrated robust prognostic stratification and predictive power across independent datasets. …"

Table 2_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.xlsx حسب Liren Fang (22489516)

"…The PRGS, established by StepCox[both]+Ridge modeling, demonstrated robust prognostic stratification and predictive power across independent datasets. …"

Image 1_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.tif حسب Liren Fang (22489516)

"…The PRGS, established by StepCox[both]+Ridge modeling, demonstrated robust prognostic stratification and predictive power across independent datasets. …"

Image 4_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.tif حسب Liren Fang (22489516)

"…The PRGS, established by StepCox[both]+Ridge modeling, demonstrated robust prognostic stratification and predictive power across independent datasets. …"

Table 1_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.xlsx حسب Liren Fang (22489516)

"…The PRGS, established by StepCox[both]+Ridge modeling, demonstrated robust prognostic stratification and predictive power across independent datasets. …"

Image 2_Single-cell and machine learning-based pyroptosis-related gene signature predicts prognosis and immunotherapy response in glioblastoma.tif حسب Liren Fang (22489516)

"…The PRGS, established by StepCox[both]+Ridge modeling, demonstrated robust prognostic stratification and predictive power across independent datasets. …"

Table 1_Development of an alkaliptosis-related lncRNA risk model and immunotherapy target analysis in lung adenocarcinoma.docx حسب Xiang Xiong (1810234)

"…The progression-free survival (PFS) and overall survival (OS) rates of the low-risk group were significantly higher than those of the high-risk group. The risk signature functions as a prognostic factor that is independent of other variables. …"

Supplementary file 1_Integrating bioinformatics and molecular experiments to reveal the critical role of the cellular energy metabolism-related marker PLA2G1B in COPD epithelial ce... حسب Jun Shi (289433)

"…Subsequently, five machine learning algorithms—Boruta, Xgboost, GBM, SVM-RFE, and LASSO—were employed to screen for key variables. …"

Collaborative research: CyberTraining: Implementation: Medium: Training users, developers, and instructors at the chemistry/physics/materials science interface حسب Francesco Paesani (5128004)

"…The primary objectives are to establish a robust community of materials modeling developers and to enhance computational training at both undergraduate and graduate levels. The project seeks to recruit and train future leaders in materials modeling, foster community engagement, and promote coding literacy across disciplines.…"

Table 1_Integrating bioinformatics and molecular experiments to reveal the critical role of the cellular energy metabolism-related marker PLA2G1B in COPD epithelial cells.xlsx حسب Jun Shi (289433)

"…Subsequently, five machine learning algorithms—Boruta, Xgboost, GBM, SVM-RFE, and LASSO—were employed to screen for key variables. …"

Patentability of 3D bioprinting technologies حسب Phoebe Li (4463947)

"…</p><p dir="ltr">(5) <i>In vitro</i> bioprinted (functional or cosmetic) human organs may be patentable.…"

IUTF Dataset(Enhanced): Enabling Cross-Border Resource for Analysing the Impact of Rainfall on Urban Transportation Systems حسب Xuhui Lin (19505503)

"…</p><h2>Data Structure</h2><p dir="ltr">The dataset is organized into four primary components:</p><ol><li><b>Road Network Data</b>: Topological representations including spatial geometry, functional classification, and connectivity information</li><li><b>Traffic Sensor Data</b>: Sensor metadata, locations, and measurements at both 5-minute and hourly resolutions</li><li><b>Precipitation Data</b>: Hourly meteorological information with spatial grid cell metadata</li><li><b>Derived Analytical Matrices</b>: Pre-computed structures for advanced spatial-temporal modelling and network analyses</li></ol><h2>File Formats</h2><ul><li><b>Tabular Data</b>: Apache Parquet format for optimal compression and fast query performance</li><li><b>Numerical Matrices</b>: NumPy NPZ format for efficient scientific computing</li><li><b>Total Size</b>: Approximately 2 GB uncompressed</li></ul><h2>Applications</h2><p dir="ltr">The IUTF dataset enables diverse analytical applications including:</p><ul><li><b>Traffic Flow Prediction</b>: Developing weather-aware traffic forecasting models</li><li><b>Infrastructure Planning</b>: Identifying vulnerable network components and prioritizing investments</li><li><b>Resilience Assessment</b>: Quantifying system recovery curves, robustness metrics, and adaptive capacity</li><li><b>Climate Adaptation</b>: Supporting evidence-based transportation planning under changing precipitation patterns</li><li><b>Emergency Management</b>: Improving response strategies for weather-related traffic disruptions</li></ul><h2>Methodology</h2><p dir="ltr">The dataset creation involved three main stages:</p><ol><li><b>Data Collection</b>: Sourcing traffic data from UTD19, road networks from OpenStreetMap, and precipitation data from ERA5 reanalysis</li><li><b>Spatio-Temporal Harmonization</b>: Comprehensive integration using novel algorithms for spatial alignment and temporal synchronization</li><li><b>Quality Assurance</b>: Rigorous validation and technical verification across all cities and data components</li></ol><h2>Code Availability</h2><p dir="ltr">Processing code is available at: https://github.com/viviRG2024/IUTDF_processing</p>…"

Table 1_Prognostic and immunological implications of cathepsin Z overexpression in prostate cancer.docx حسب Junyue Tao (13817719)

"…Immunohistochemical staining and multiplex immunofluorescence staining were performed to evaluate the expression and spatial distribution of CTSZ and immune-related markers in PCa tissues. Functional studies were conducted through a series of experiments, including CCK-8 assay, colony formation, wound healing, and Transwell migration assays. ssGSEA and CIBERSORT algorithms immune infiltration evaluation, and GISTIC2.0 and MutSigCV for tumor mutation burden. …"

Data Sheet 1_Differential neuropilin isoform expressions highlight plasticity in macrophages in the heterogenous TME through in-silico profiling.docx حسب Hyun-Jee Han (20858765)

"…Datasets were processed using established bioinformatics pipelines, including clustering algorithms, to determine cellular heterogeneity and quantify NRP isoform expression within distinct macrophage populations. …"

Etodolac utility in osteoarthritis: drug delivery challenges, topical nanotherapeutic strategies and potential synergies حسب Pavani Gaddala (19761334)

"…Emphasis is placed on the pivotal role of etodolac in OSA management, supported by both preclinical and clinical evidences in topical drug delivery. …"

Data Sheet 2_Differential neuropilin isoform expressions highlight plasticity in macrophages in the heterogenous TME through in-silico profiling.docx حسب Hyun-Jee Han (20858765)

"…Datasets were processed using established bioinformatics pipelines, including clustering algorithms, to determine cellular heterogeneity and quantify NRP isoform expression within distinct macrophage populations. …"

Image 4_Machine learning-based diagnostic and prognostic models for breast cancer: a new frontier on the clinical application of natural killer cell-related gene signatures in prec... حسب Yutong Fang (16621143)

"…We constructed ML-based diagnostic models using 12 algorithms and evaluated their performance for identifying the optimal ML diagnostic model. …"

Image 8_Machine learning-based diagnostic and prognostic models for breast cancer: a new frontier on the clinical application of natural killer cell-related gene signatures in prec... حسب Yutong Fang (16621143)

"…We constructed ML-based diagnostic models using 12 algorithms and evaluated their performance for identifying the optimal ML diagnostic model. …"