Image 1_Single-cell sequencing reveals the role of aggrephagy-related patterns in tumor microenvironment, prognosis and immunotherapy in endometrial cancer.jpeg حسب Yuquan Yuan (10570747)

"…However, aggrephagy functions within the tumor microenvironment (TME) in endometrial cancer (EC) remain to be elucidated.…"

Image 3_Single-cell sequencing reveals the role of aggrephagy-related patterns in tumor microenvironment, prognosis and immunotherapy in endometrial cancer.jpeg حسب Yuquan Yuan (10570747)

"…However, aggrephagy functions within the tumor microenvironment (TME) in endometrial cancer (EC) remain to be elucidated.…"

Table 1_Single-cell sequencing reveals the role of aggrephagy-related patterns in tumor microenvironment, prognosis and immunotherapy in endometrial cancer.docx حسب Yuquan Yuan (10570747)

"…However, aggrephagy functions within the tumor microenvironment (TME) in endometrial cancer (EC) remain to be elucidated.…"

Image 4_Single-cell sequencing reveals the role of aggrephagy-related patterns in tumor microenvironment, prognosis and immunotherapy in endometrial cancer.jpeg حسب Yuquan Yuan (10570747)

"…However, aggrephagy functions within the tumor microenvironment (TME) in endometrial cancer (EC) remain to be elucidated.…"

Table 2_Single-cell sequencing reveals the role of aggrephagy-related patterns in tumor microenvironment, prognosis and immunotherapy in endometrial cancer.docx حسب Yuquan Yuan (10570747)

"…However, aggrephagy functions within the tumor microenvironment (TME) in endometrial cancer (EC) remain to be elucidated.…"

Data Sheet 1_Identification of key biomarkers related to fibrocartilage chondrocytes for osteoarthritis based on bulk, single-cell transcriptomic data.docx حسب Bailin Pan (20300112)

"…</p>Conclusion<p>This study used a multi-omics approach to identify six FC-related OA biomarkers (BCL6, ABCA5, ABCA6, CITED2, NR1D1, and SLC7A8) and developed an exploratory risk model. Functional enrichment analysis revealed that the FoxO pathway may be linked to these markers, particularly implicating ABCA5 and ABCA6 in cholesterol homeostasis within chondrocytes. …"

Data Sheet 2_Identification of key biomarkers related to fibrocartilage chondrocytes for osteoarthritis based on bulk, single-cell transcriptomic data.csv حسب Bailin Pan (20300112)

"…</p>Conclusion<p>This study used a multi-omics approach to identify six FC-related OA biomarkers (BCL6, ABCA5, ABCA6, CITED2, NR1D1, and SLC7A8) and developed an exploratory risk model. Functional enrichment analysis revealed that the FoxO pathway may be linked to these markers, particularly implicating ABCA5 and ABCA6 in cholesterol homeostasis within chondrocytes. …"

Table 1_A novel prognostic signature identifies MFAP4 as a tumor suppressor linking the tumor microenvironment to PI3K/AKT signaling in triple-negative breast cancer.docx حسب Xiaoqin Yu (3918377)

"…The model’s association with TME characteristics was assessed using ESTIMATE algorithm and immune infiltration analyses. The biological functions of the key gene, Microfibril Associated Protein 4 (MFAP4), were investigated in vitro via proliferation and migration assays. …"

Table 2_A novel prognostic signature identifies MFAP4 as a tumor suppressor linking the tumor microenvironment to PI3K/AKT signaling in triple-negative breast cancer.xlsx حسب Xiaoqin Yu (3918377)

"…The model’s association with TME characteristics was assessed using ESTIMATE algorithm and immune infiltration analyses. The biological functions of the key gene, Microfibril Associated Protein 4 (MFAP4), were investigated in vitro via proliferation and migration assays. …"

Data Sheet 1_A novel prognostic signature identifies MFAP4 as a tumor suppressor linking the tumor microenvironment to PI3K/AKT signaling in triple-negative breast cancer.pdf حسب Xiaoqin Yu (3918377)

"…The model’s association with TME characteristics was assessed using ESTIMATE algorithm and immune infiltration analyses. The biological functions of the key gene, Microfibril Associated Protein 4 (MFAP4), were investigated in vitro via proliferation and migration assays. …"

Data Sheet 1_Development of the TSR-based computational method to investigate spike and monoclonal antibody interactions.pdf حسب Tarikul I. Milon (20524622)

"…In some instances, a direct correlation between structures and functions was successfully established.</p>…"

Data Sheet 2_Characterization of the salivary microbiome in healthy individuals under fatigue status.docx حسب Xianhui Peng (14551488)

"…Bioinformatics analyses encompassed assessment of alpha and beta diversity, identification of differential taxa using Linear discriminant analysis Effect Size (LEfSe) with multi-method cross-validation, construction of microbial co-occurrence networks, and screening of fatigue-associated biomarker genera via the Boruta-SHAP algorithm. Microbial community phenotypes and potential functional pathways were predicted using BugBase and PICRUSt2, respectively.…"

Table 3_Characterization of the salivary microbiome in healthy individuals under fatigue status.xlsx حسب Xianhui Peng (14551488)

"…Bioinformatics analyses encompassed assessment of alpha and beta diversity, identification of differential taxa using Linear discriminant analysis Effect Size (LEfSe) with multi-method cross-validation, construction of microbial co-occurrence networks, and screening of fatigue-associated biomarker genera via the Boruta-SHAP algorithm. Microbial community phenotypes and potential functional pathways were predicted using BugBase and PICRUSt2, respectively.…"

Data Sheet 1_Characterization of the salivary microbiome in healthy individuals under fatigue status.docx حسب Xianhui Peng (14551488)

"…Bioinformatics analyses encompassed assessment of alpha and beta diversity, identification of differential taxa using Linear discriminant analysis Effect Size (LEfSe) with multi-method cross-validation, construction of microbial co-occurrence networks, and screening of fatigue-associated biomarker genera via the Boruta-SHAP algorithm. Microbial community phenotypes and potential functional pathways were predicted using BugBase and PICRUSt2, respectively.…"

Table 5_Characterization of the salivary microbiome in healthy individuals under fatigue status.xlsx حسب Xianhui Peng (14551488)

"…Bioinformatics analyses encompassed assessment of alpha and beta diversity, identification of differential taxa using Linear discriminant analysis Effect Size (LEfSe) with multi-method cross-validation, construction of microbial co-occurrence networks, and screening of fatigue-associated biomarker genera via the Boruta-SHAP algorithm. Microbial community phenotypes and potential functional pathways were predicted using BugBase and PICRUSt2, respectively.…"

Table 4_Characterization of the salivary microbiome in healthy individuals under fatigue status.xlsx حسب Xianhui Peng (14551488)

"…Bioinformatics analyses encompassed assessment of alpha and beta diversity, identification of differential taxa using Linear discriminant analysis Effect Size (LEfSe) with multi-method cross-validation, construction of microbial co-occurrence networks, and screening of fatigue-associated biomarker genera via the Boruta-SHAP algorithm. Microbial community phenotypes and potential functional pathways were predicted using BugBase and PICRUSt2, respectively.…"

Table 2_Characterization of the salivary microbiome in healthy individuals under fatigue status.xlsx حسب Xianhui Peng (14551488)

"…Bioinformatics analyses encompassed assessment of alpha and beta diversity, identification of differential taxa using Linear discriminant analysis Effect Size (LEfSe) with multi-method cross-validation, construction of microbial co-occurrence networks, and screening of fatigue-associated biomarker genera via the Boruta-SHAP algorithm. Microbial community phenotypes and potential functional pathways were predicted using BugBase and PICRUSt2, respectively.…"

Table 1_Characterization of the salivary microbiome in healthy individuals under fatigue status.xlsx حسب Xianhui Peng (14551488)

"…Bioinformatics analyses encompassed assessment of alpha and beta diversity, identification of differential taxa using Linear discriminant analysis Effect Size (LEfSe) with multi-method cross-validation, construction of microbial co-occurrence networks, and screening of fatigue-associated biomarker genera via the Boruta-SHAP algorithm. Microbial community phenotypes and potential functional pathways were predicted using BugBase and PICRUSt2, respectively.…"

Image 1_Targeting a distinct binding pocket in the pregnane X receptor with natural agonist TRLW-2 ameliorates murine ulcerative colitis.tif حسب Shangrui Rao (18189241)

"…</p>Methods<p>A distinct binding pocket (Pocket 1–5) within the PXR ligand-binding domain was identified using a multi-algorithm computational approach (SiteMap, Fpocket, Prank, CASTpFold). …"

Image 2_Targeting a distinct binding pocket in the pregnane X receptor with natural agonist TRLW-2 ameliorates murine ulcerative colitis.tif حسب Shangrui Rao (18189241)

"…</p>Methods<p>A distinct binding pocket (Pocket 1–5) within the PXR ligand-binding domain was identified using a multi-algorithm computational approach (SiteMap, Fpocket, Prank, CASTpFold). …"