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2401
Image 2_Integrating bioinformatics and machine learning analyses to identify immune-related secretory proteins and therapeutic small-molecule drugs in calcific aortic valve disease...
Published 2025“…A diagnostic model was constructed using 113 machine learning algorithms, and immune infiltration analysis was performed using CIBERSORT. …”
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2402
Table 2_Identification and validation of icaritin-associated prognostic genes in hepatocellular carcinoma through network pharmacology, bioinformatics analysis, and cellular experi...
Published 2025“…</p>Results<p>We identified thirty-five overlapping targets between ICT and HCC, and functional enrichment analysis showed that these genes are primarily implicated in cell cycle regulation and glycolytic pathways, highlighting potential mechanisms through which ICT exerts its antitumor effects. …”
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2403
Data Sheet 2_Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.csv
Published 2025“…Machine learning (10 algorithms) was employed to construct diagnostic models, and SHAP analysis was applied to assess key gene contributions. …”
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2404
Data Sheet 1_Inflammation-related biomarkers and berberine therapy in post-stroke depression: evidence from bioinformatics, machine learning, and experimental validation.docx
Published 2025“…Differentially expressed genes (DEGs) were identified using the limma package, followed by functional enrichment analysis with Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). …”
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2405
Data Sheet 5_Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.csv
Published 2025“…Machine learning (10 algorithms) was employed to construct diagnostic models, and SHAP analysis was applied to assess key gene contributions. …”
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2406
Table 1_Prognostic and immunological implications of cathepsin Z overexpression in prostate cancer.docx
Published 2025“…Immunohistochemical staining and multiplex immunofluorescence staining were performed to evaluate the expression and spatial distribution of CTSZ and immune-related markers in PCa tissues. Functional studies were conducted through a series of experiments, including CCK-8 assay, colony formation, wound healing, and Transwell migration assays. ssGSEA and CIBERSORT algorithms immune infiltration evaluation, and GISTIC2.0 and MutSigCV for tumor mutation burden. …”
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2407
Data Sheet 4_Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.csv
Published 2025“…Machine learning (10 algorithms) was employed to construct diagnostic models, and SHAP analysis was applied to assess key gene contributions. …”
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2408
Data Sheet 1_Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.csv
Published 2025“…Machine learning (10 algorithms) was employed to construct diagnostic models, and SHAP analysis was applied to assess key gene contributions. …”
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2409
Data Sheet 3_Integration of multi-omics and machine learning strategies identifies immune related candidate biomarkers in inflammation-associated hypertrophic cardiomyopathy.csv
Published 2025“…Machine learning (10 algorithms) was employed to construct diagnostic models, and SHAP analysis was applied to assess key gene contributions. …”
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2410
Construction of a novel radioresistance-related signature for prediction of prognosis, immune microenvironment and anti-tumour drug sensitivity in non-small cell lung cancer
Published 2025“…Then, Immune landscape and drug sensitivity were evaluated. The biological functions exerted by the key gene <i>LBH</i> were verified by <i>in vitro</i> experiments.…”
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2411
<b>dGenhancer v2</b>: A software tool for designing oligonucleotides that can trigger gene-specific Enhancement of Protein Translation.
Published 2024“…<br> An excel-based calculator - dGenhancer can be used to search for putative 5’UTR cis-acting elements, which functional activity could be determined by Gibbs energy-dependent secondary structure formation. …”
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2412
AP-2α 相关研究
Published 2025“…The Gene Ontology (GO) database categorizes genes based on biological processes, cellular components, and molecular functions. The y-axis lists GO secondary terms, the x-axis shows the number of genes/transcripts assigned to each term, and colors represent different gene sets.…”