Data Sheet 2_Key gene screening and diagnostic model establishment for acute type a aortic dissection.csv حسب Yue Pan (267516)

"…</p>Methods<p>Transcriptome datasets from the Gene Expression Omnibus (GEO) database were analyzed using differential expression analysis, weighted gene co-expression network analysis (WGCNA), and machine learning algorithms (SVM, Random Forest, LASSO regression). Functional enrichment and immunoinfiltration analyses were performed to explore biological pathways and immune cell interactions. …"

Table 1_Key gene screening and diagnostic model establishment for acute type a aortic dissection.xlsx حسب Yue Pan (267516)

"…</p>Methods<p>Transcriptome datasets from the Gene Expression Omnibus (GEO) database were analyzed using differential expression analysis, weighted gene co-expression network analysis (WGCNA), and machine learning algorithms (SVM, Random Forest, LASSO regression). Functional enrichment and immunoinfiltration analyses were performed to explore biological pathways and immune cell interactions. …"

Data Sheet 4_Key gene screening and diagnostic model establishment for acute type a aortic dissection.csv حسب Yue Pan (267516)

"…</p>Methods<p>Transcriptome datasets from the Gene Expression Omnibus (GEO) database were analyzed using differential expression analysis, weighted gene co-expression network analysis (WGCNA), and machine learning algorithms (SVM, Random Forest, LASSO regression). Functional enrichment and immunoinfiltration analyses were performed to explore biological pathways and immune cell interactions. …"

Data Sheet 5_Key gene screening and diagnostic model establishment for acute type a aortic dissection.csv حسب Yue Pan (267516)

"…</p>Methods<p>Transcriptome datasets from the Gene Expression Omnibus (GEO) database were analyzed using differential expression analysis, weighted gene co-expression network analysis (WGCNA), and machine learning algorithms (SVM, Random Forest, LASSO regression). Functional enrichment and immunoinfiltration analyses were performed to explore biological pathways and immune cell interactions. …"

Data Sheet 1_Key gene screening and diagnostic model establishment for acute type a aortic dissection.csv حسب Yue Pan (267516)

"…</p>Methods<p>Transcriptome datasets from the Gene Expression Omnibus (GEO) database were analyzed using differential expression analysis, weighted gene co-expression network analysis (WGCNA), and machine learning algorithms (SVM, Random Forest, LASSO regression). Functional enrichment and immunoinfiltration analyses were performed to explore biological pathways and immune cell interactions. …"

Data Sheet 1_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx حسب Wentong Li (492392)

"…Biomarker validation was performed through cross-validation using LASSO, SVM-RFE, and Random Forest algorithms. Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.…"

Data Sheet 5_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.csv حسب Wentong Li (492392)

"…Biomarker validation was performed through cross-validation using LASSO, SVM-RFE, and Random Forest algorithms. Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.…"

Supplementary file 1_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.docx حسب Wentong Li (492392)

"…Biomarker validation was performed through cross-validation using LASSO, SVM-RFE, and Random Forest algorithms. Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.…"

Data Sheet 2_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx حسب Wentong Li (492392)

"…Biomarker validation was performed through cross-validation using LASSO, SVM-RFE, and Random Forest algorithms. Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.…"

Data Sheet 3_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx حسب Wentong Li (492392)

"…Biomarker validation was performed through cross-validation using LASSO, SVM-RFE, and Random Forest algorithms. Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.…"

Data Sheet 4_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx حسب Wentong Li (492392)

"…Biomarker validation was performed through cross-validation using LASSO, SVM-RFE, and Random Forest algorithms. Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.…"

Supplementary file 1_Transcriptomic analysis and machine learning modeling identifies novel biomarkers and genetic characteristics of hypertrophic cardiomyopathy.xlsx حسب Feng Zhang (6548)

"…A predictive model for HCM was developed through systematic evaluation of 113 combinations of 12 machine-learning algorithms, employing 10-fold cross-validation on training datasets and external validation using an independent cohort (GSE180313).…"

Table 1_Integrative multi-omics analysis identifies a PTM-related immune signature and IRF9 as a driver in ccRCC.docx حسب Zixiang Li (7014416)

"…</p>Results<p>We established a five-gene PTMRS that robustly stratified prognosis in training, testing, and external cohorts and remained an independent predictor. …"

Supplementary file 1_Integrative multi-omics analysis identifies a PTM-related immune signature and IRF9 as a driver in ccRCC.docx حسب Zixiang Li (7014416)

"…</p>Results<p>We established a five-gene PTMRS that robustly stratified prognosis in training, testing, and external cohorts and remained an independent predictor. …"

Table 2_Integrative multi-omics analysis identifies a PTM-related immune signature and IRF9 as a driver in ccRCC.docx حسب Zixiang Li (7014416)

"…</p>Results<p>We established a five-gene PTMRS that robustly stratified prognosis in training, testing, and external cohorts and remained an independent predictor. …"

Data Sheet 1_COL8A1 as a pro-inflammatory mediator bridges immune evasion and therapy resistance in glioma.docx حسب Jiachong Wang (22818095)

"…The suppression of tumor migration and proliferation by COL8A1 knockdown was validated by functional tests. Multiple immunotherapy determinants, inhibitory immunological checkpoints, and immune cell infiltration all showed high correlations with COL8A1 expression. …"

Data Sheet 1_Inflammation-related biomarkers and berberine therapy in post-stroke depression: evidence from bioinformatics, machine learning, and experimental validation.docx حسب Wei Liu (20030)

"…Three machine learning algorithms—random forest, support vector machine-recursive feature elimination (SVM-RFE), and least absolute shrinkage and selection operator (LASSO)—were applied to screen inflammation-related hub genes. …"

DataSheet1_Extrachromosomal circular DNAs in prostate adenocarcinoma: global characterizations and a novel prediction model.PDF حسب Qingliu He (12528332)

"…Following that, 499 eDEGs were tested in conjunction with the transcriptome dataset from TCGA-PRAD. …"

Presentation1_Extrachromosomal circular DNAs in prostate adenocarcinoma: global characterizations and a novel prediction model.pdf حسب Qingliu He (12528332)

"…Following that, 499 eDEGs were tested in conjunction with the transcriptome dataset from TCGA-PRAD. …"

<b>dGenhancer v2</b>: A software tool for designing oligonucleotides that can trigger gene-specific Enhancement of Protein Translation. حسب Adam Master (20316450)

"…<br> This version requires pre-calculated total Gibbs energies of the tested sequences. Prediction of total Gibbs energies (ΔG=ΔH–TΔS) of the 5’UTR structures can be performed using RNAstructure version 5.2. …"