Image 1_Unveiling purine metabolism dysregulation orchestrated immunosuppression in advanced pancreatic cancer and concentrating on the central role of NT5E.pdf by Junqian Zhang (9315639)

“…The by-products of purine metabolic reprogramming are extensively engaged in tumor immune modulation, influencing the functions and recruitment of immune cells and molding an immune microenvironment that is propitious for tumor growth.…”

Table 1_Identification and validation of key biomarkers of the glycolysis-ketone body metabolism in heart failure based on multi-omics and machine learning.xlsx by Na Xiao (327834)

“…Candidate genes were refined using machine learning algorithms (LASSO regression and Boruta), with functional enrichment assessed via Gene Set Enrichment Analysis (GSEA). …”

Image 1_Identification and validation of key biomarkers of the glycolysis-ketone body metabolism in heart failure based on multi-omics and machine learning.pdf by Na Xiao (327834)

“…Candidate genes were refined using machine learning algorithms (LASSO regression and Boruta), with functional enrichment assessed via Gene Set Enrichment Analysis (GSEA). …”

Table 1_Neurochallenges in smart cities: state-of-the-art, perspectives, and research directions.docx by Begüm Özkaynak (20445146)

“…<p>Smart city development is a complex, transdisciplinary challenge that requires adaptive resource use and context-aware decision-making practices to enhance human functionality and capabilities while respecting societal and environmental rights, and ethics. …”

Data Sheet 1_COL8A1 as a pro-inflammatory mediator bridges immune evasion and therapy resistance in glioma.docx by Jiachong Wang (22818095)

“…</p>Findings<p>COL8A1 was found to be a significant prognostic gene within a highly linked gene module connected to inflammation. …”

Table1_“Dictionary of immune responses” reveals the critical role of monocytes and the core target IRF7 in intervertebral disc degeneration.xls by Peichuan Xu (19862055)

“…Cytokines facilitate intercellular communication within the immune system, induce immune cells polarisation, and exacerbate oxidative stress in IDD. …”

Image2_“Dictionary of immune responses” reveals the critical role of monocytes and the core target IRF7 in intervertebral disc degeneration.jpeg by Peichuan Xu (19862055)

“…Cytokines facilitate intercellular communication within the immune system, induce immune cells polarisation, and exacerbate oxidative stress in IDD. …”

Image1_“Dictionary of immune responses” reveals the critical role of monocytes and the core target IRF7 in intervertebral disc degeneration.jpeg by Peichuan Xu (19862055)

“…Cytokines facilitate intercellular communication within the immune system, induce immune cells polarisation, and exacerbate oxidative stress in IDD. …”

Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip by Erli Wu (17785482)

“…By integrating bulk transcriptomic data with machine learning algorithms, we identified and validated key PANoptosis-related genes, highlighting their potential as novel therapeutic targets.…”

Data Sheet 1_Integrative multi-omics identifies MEIS3 as a diagnostic biomarker and immune modulator in hypertrophic cardiomyopathy.docx by Jinchen He (18929662)

“…Machine learning algorithms (LASSO and Random Forest) were used to identify key diagnostic genes. …”

Data Sheet 1_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx by Wentong Li (492392)

“…Biomarker validation was performed through cross-validation using LASSO, SVM-RFE, and Random Forest algorithms. Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.…”

Data Sheet 5_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.csv by Wentong Li (492392)

“…Biomarker validation was performed through cross-validation using LASSO, SVM-RFE, and Random Forest algorithms. Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.…”

Supplementary file 1_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.docx by Wentong Li (492392)

“…Biomarker validation was performed through cross-validation using LASSO, SVM-RFE, and Random Forest algorithms. Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.…”

Data Sheet 2_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx by Wentong Li (492392)

“…Biomarker validation was performed through cross-validation using LASSO, SVM-RFE, and Random Forest algorithms. Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.…”

Data Sheet 3_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx by Wentong Li (492392)

“…Biomarker validation was performed through cross-validation using LASSO, SVM-RFE, and Random Forest algorithms. Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.…”

Data Sheet 4_Multi-omics exploration of chaperone-mediated immune-proteostasis crosstalk in vascular dementia and identification of diagnostic biomarkers.xlsx by Wentong Li (492392)

“…Biomarker validation was performed through cross-validation using LASSO, SVM-RFE, and Random Forest algorithms. Immune microenvironment analysis was conducted using CIBERSORT, while single-cell transcriptomics was analyzed within the Seurat framework.…”

Consensus group. by Yinghao Ren (17915291)

“…We also identified differentially expressed genes (DEGs) within the clusters and between SLE patients and healthy controls. …”

GSVA pathway. by Yinghao Ren (17915291)

“…We also identified differentially expressed genes (DEGs) within the clusters and between SLE patients and healthy controls. …”

Hallmark significant GSVA results. by Yinghao Ren (17915291)

“…We also identified differentially expressed genes (DEGs) within the clusters and between SLE patients and healthy controls. …”

RBP table. by Yinghao Ren (17915291)

“…We also identified differentially expressed genes (DEGs) within the clusters and between SLE patients and healthy controls. …”