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    PATH has state-of-the-art performance versus previous binding affinity prediction algorithms. by Yuxi Long (11024307)

    Published 2025
    “…The benchmarked algorithms include physics-based and deep learning algorithms from the famous AutoDock framework (scoring function of AutoDock4 implemented in the AutoDockFR package [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013216#pcbi.1013216.ref068" target="_blank">68</a>,<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013216#pcbi.1013216.ref077" target="_blank">77</a>], Vinardo [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013216#pcbi.1013216.ref069" target="_blank">69</a>], GNINA [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013216#pcbi.1013216.ref070" target="_blank">70</a>]), empirical (AA-Score [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013216#pcbi.1013216.ref071" target="_blank">71</a>]), knowledge-based (SMoG2016 [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013216#pcbi.1013216.ref072" target="_blank">72</a>]), and deep learning-based scoring functions (OnionNet [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013216#pcbi.1013216.ref073" target="_blank">73</a>], PLANET [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013216#pcbi.1013216.ref074" target="_blank">74</a>]). …”
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