Image1_“Dictionary of immune responses” reveals the critical role of monocytes and the core target IRF7 in intervertebral disc degeneration.jpeg حسب Peichuan Xu (19862055)

"…Cytokines facilitate intercellular communication within the immune system, induce immune cells polarisation, and exacerbate oxidative stress in IDD. …"

Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip حسب Erli Wu (17785482)

"…By integrating bulk transcriptomic data with machine learning algorithms, we identified and validated key PANoptosis-related genes, highlighting their potential as novel therapeutic targets.…"

Table 2_Identification of regulatory cell death-related genes during MASH progression using bioinformatics analysis and machine learning strategies.xlsx حسب Zhiqiang Lin (747094)

"…WB results showed that the protein level of EPHA3 significantly increased in both mouse models of liver fibrosis. …"

Table 1_Identification of regulatory cell death-related genes during MASH progression using bioinformatics analysis and machine learning strategies.xlsx حسب Zhiqiang Lin (747094)

"…WB results showed that the protein level of EPHA3 significantly increased in both mouse models of liver fibrosis. …"

Data Sheet 1_Resveratrol contributes to NK cell-mediated breast cancer cytotoxicity by upregulating ULBP2 through miR-17-5p downmodulation and activation of MINK1/JNK/c-Jun signali... حسب Bisha Ding (5803799)

"…Natural killer group 2 member D (NKG2D) is a prominent activating receptor of NK cell. UL16-binding protein 2 (ULBP2), always expressed or elevated on cancer cells, functions as a key NKG2D ligand. …"

Etodolac utility in osteoarthritis: drug delivery challenges, topical nanotherapeutic strategies and potential synergies حسب Pavani Gaddala (19761334)

"…Inflammatory processes within OSA joints are regulated by pro-inflammatory and anti-inflammatory cytokines. …"

Image 1_Characterization of cancer-related fibroblasts in bladder cancer and construction of CAFs-based bladder cancer classification: insights from single-cell and multi-omics ana... حسب Zhaokai Zhou (15239078)

"…Moreover, machine learning algorithms were applied to identify novel potential targets for each subtype, and experimentally validate their effects.…"

Table 1_Characterization of cancer-related fibroblasts in bladder cancer and construction of CAFs-based bladder cancer classification: insights from single-cell and multi-omics ana... حسب Zhaokai Zhou (15239078)

"…Moreover, machine learning algorithms were applied to identify novel potential targets for each subtype, and experimentally validate their effects.…"

Image 2_Characterization of cancer-related fibroblasts in bladder cancer and construction of CAFs-based bladder cancer classification: insights from single-cell and multi-omics ana... حسب Zhaokai Zhou (15239078)

"…Moreover, machine learning algorithms were applied to identify novel potential targets for each subtype, and experimentally validate their effects.…"

AP-2α 相关研究 حسب Ya-Hong Wang (21080642)

"…</p><p dir="ltr">(D) Phylogenetic analysis of the <i>VdAP-2α</i> protein in <i>V. dahliae</i> and its homologs in other fungi. …"

Table 1_Shared genetic architecture between COVID-19 and irritable bowel syndrome: a large-scale genome-wide cross-trait analysis.xlsx حسب Xianqiang Liu (228089)

"…Independent risk loci were examined using genome-wide complex trait analysis (GCTA)-conditional and joint analysis (COJO), multi-marker analysis of genomic annotation (MAGMA), and functional mapping and annotation (FUMA), integrating various QTL information and methods to further identify risk genes and proteins. …"

Image 3_Integrating scRNA-seq and machine learning identifies MNAT1 as a therapeutic target in OSCC.tif حسب Han Gao (486886)

"…In vitro functional assays showed that depletion of MNAT1 impaired Cal27 cell proliferation and migration capacity.…"

Image 2_Integrating scRNA-seq and machine learning identifies MNAT1 as a therapeutic target in OSCC.tif حسب Han Gao (486886)

"…In vitro functional assays showed that depletion of MNAT1 impaired Cal27 cell proliferation and migration capacity.…"

Image 1_Integrating scRNA-seq and machine learning identifies MNAT1 as a therapeutic target in OSCC.tif حسب Han Gao (486886)

"…In vitro functional assays showed that depletion of MNAT1 impaired Cal27 cell proliferation and migration capacity.…"

Table 1_Integrating scRNA-seq and machine learning identifies MNAT1 as a therapeutic target in OSCC.docx حسب Han Gao (486886)

"…In vitro functional assays showed that depletion of MNAT1 impaired Cal27 cell proliferation and migration capacity.…"

Image 4_Integrating scRNA-seq and machine learning identifies MNAT1 as a therapeutic target in OSCC.tif حسب Han Gao (486886)

"…In vitro functional assays showed that depletion of MNAT1 impaired Cal27 cell proliferation and migration capacity.…"

Image 1_Integrated bioinformatics and molecular docking analysis reveal potential hub genes and targeted therapeutics in sepsis-associated acute lung injury.jpeg حسب Qiongyan Chen (22406809)

"…Hub genes were screened using PPI network construction and three machine learning algorithms, and validated by Western blot. Functional enrichment, immune infiltration, and drug prediction (DSigDB) were performed, followed by molecular docking.…"

Table 1_Integrated bioinformatics and molecular docking analysis reveal potential hub genes and targeted therapeutics in sepsis-associated acute lung injury.docx حسب Qiongyan Chen (22406809)

"…Hub genes were screened using PPI network construction and three machine learning algorithms, and validated by Western blot. Functional enrichment, immune infiltration, and drug prediction (DSigDB) were performed, followed by molecular docking.…"

Table 2_Integrated bioinformatics and molecular docking analysis reveal potential hub genes and targeted therapeutics in sepsis-associated acute lung injury.docx حسب Qiongyan Chen (22406809)

"…Hub genes were screened using PPI network construction and three machine learning algorithms, and validated by Western blot. Functional enrichment, immune infiltration, and drug prediction (DSigDB) were performed, followed by molecular docking.…"

Data Sheet 1_Inflammation-related biomarkers and berberine therapy in post-stroke depression: evidence from bioinformatics, machine learning, and experimental validation.docx حسب Wei Liu (20030)

"…Differentially expressed genes (DEGs) were identified using the limma package, followed by functional enrichment analysis with Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). …"