Search alternatives:
cell decrease » cell disease (Expand Search), mean decrease (Expand Search), cell release (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
cell decrease » cell disease (Expand Search), mean decrease (Expand Search), cell release (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
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Downregulation of lumican enhanced mitotic defects and aneuploidy in lung cancer cells
Published 2019“…Notably, the downregulation of lumican decreased the level of MKLP1 accompanied by the retention of midbody-residual that resulted in multi-nucleated cells. …”
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Table2_Artificially Increasing Cortical Tension Improves Mouse Oocytes Development by Attenuating Meiotic Defects During Vitrification.XLSX
Published 2022“…Furthermore, increasing the cortical tension could improve spindle positioning, maintain kinetochore-microtubule (KT-MT) attachment, strengthen spindle assembly checkpoint (SAC) activity, and reduce the aneuploidy rate in vitrified oocytes. In conclusion, vitrification induced a remarkable decrease in cortical tension, and increasing the cortical tension could rescue the meiosis defect and improve oocyte quality.…”
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Table1_Artificially Increasing Cortical Tension Improves Mouse Oocytes Development by Attenuating Meiotic Defects During Vitrification.DOCX
Published 2022“…Furthermore, increasing the cortical tension could improve spindle positioning, maintain kinetochore-microtubule (KT-MT) attachment, strengthen spindle assembly checkpoint (SAC) activity, and reduce the aneuploidy rate in vitrified oocytes. In conclusion, vitrification induced a remarkable decrease in cortical tension, and increasing the cortical tension could rescue the meiosis defect and improve oocyte quality.…”
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Elimination of protein aggregates prevents premature senescence in human trisomy 21 fibroblasts
Published 2019“…Recent studies on yeast and mammalian cells have demonstrated that aneuploidy exerts detrimental effects on organismal growth and development, regardless of the karyotype, suggesting that aneuploidy-associated stress plays an important role in disease pathogenesis. …”
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