Showing 1 - 20 results of 60 for search '(( aneuploidy cell decrease ) OR ((( euploid fold decrease ) OR ( euploid small decrease ))))*', query time: 1.84s Refine Results
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    Downregulation of lumican enhanced mitotic defects and aneuploidy in lung cancer cells by Cheng-Ta Yang (13427)

    Published 2019
    “…Notably, the downregulation of lumican decreased the level of MKLP1 accompanied by the retention of midbody-residual that resulted in multi-nucleated cells. …”
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    Table2_Artificially Increasing Cortical Tension Improves Mouse Oocytes Development by Attenuating Meiotic Defects During Vitrification.XLSX by Xingzhu Du (12282362)

    Published 2022
    “…Furthermore, increasing the cortical tension could improve spindle positioning, maintain kinetochore-microtubule (KT-MT) attachment, strengthen spindle assembly checkpoint (SAC) activity, and reduce the aneuploidy rate in vitrified oocytes. In conclusion, vitrification induced a remarkable decrease in cortical tension, and increasing the cortical tension could rescue the meiosis defect and improve oocyte quality.…”
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    Table1_Artificially Increasing Cortical Tension Improves Mouse Oocytes Development by Attenuating Meiotic Defects During Vitrification.DOCX by Xingzhu Du (12282362)

    Published 2022
    “…Furthermore, increasing the cortical tension could improve spindle positioning, maintain kinetochore-microtubule (KT-MT) attachment, strengthen spindle assembly checkpoint (SAC) activity, and reduce the aneuploidy rate in vitrified oocytes. In conclusion, vitrification induced a remarkable decrease in cortical tension, and increasing the cortical tension could rescue the meiosis defect and improve oocyte quality.…”
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    Elimination of protein aggregates prevents premature senescence in human trisomy 21 fibroblasts by Nobutoshi Nawa (7053758)

    Published 2019
    “…Recent studies on yeast and mammalian cells have demonstrated that aneuploidy exerts detrimental effects on organismal growth and development, regardless of the karyotype, suggesting that aneuploidy-associated stress plays an important role in disease pathogenesis. …”
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