The antiproliferative and pro-apoptotic effect of kefir on human leukemic cell lines. (c2008) حسب Maalouf, Katia E.

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Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation حسب Zreik, Tony

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Effects of lipid administration on liver apoptotic signals in a mouse model of total parenteral nutrition (TPN) حسب Btaiche, Imad

"…After 7 days of infusion, apoptosis increased in the TPN+L at a significantly higher rate compared with control and TPN-L groups ( p <0.05). …"
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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo حسب Daaboul, Hamid E.

"…Similar effects were observed with cisplatin treatment, but HC-treated groups exhibited twofold to threefold increase in survival rates. Similar patterns in the pro- and anti-apoptotic proteins were observed in mice treated with HC, except for a significant increase in p53 protein. …"
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells حسب Al Sayyed, Fatima

"…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …"
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Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 حسب Ramada R. Khaswaneh (22224544)

"…Preserving the level of Factor H and CD59 in MSCs has significant clinical implication to increase their retention rate in hypoxic conditions and prolong their survival.…"

Drug-free phototherapy of superficial tumors حسب Mehanna, Stephanie

"…After a 9-h exposure in vitro, the viability of Human Malignant Melanoma cells (A375) decreased by around 70%. Western blot analysis suggested an apoptotic cell death confirmed by the upregulation of Bax, cleaved PARP/caspase-3/8, cytochrome c, and t-bid. …"
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Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…With respect to the proteins studied, treatment with Urtica dioica extract significantly increased the expression of the pro-apoptotic protein Bax with concomitant decrease in the anti-apoptotic protein Bcl-2 expression. …"
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Therapeutic Impact of P-PENT, P-HEX and 5CLSS (IV) Platinum (IV) complexes on Acute Myeloid Leukemia in vitro and in vivo حسب Bou Chacra, Joelle

"…Western blots analysis confirmed the involvement of an intrinsic apoptotic pathway (BAX/BCL2, procaspase 3, full length PARP )and inhibition of the MAPK pathway (P-ERK/ERK) . …"
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In Vitro and In Vivo Effects of Lebanese Cannabis Oil Against Acute Myeloid Leukemia (AML) حسب Lteif, Anthony

"…Animals treated with COE exhibited a higher survival rate and a significant reduction in spleen weight. …"
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Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... حسب Farhat, Mirna

"…We showed evidence that PAU2R200A/FP59, from the IMC variant, induced a cytotoxic response that matched the pattern of IMC/FP59, as such indicating that uPA/uPAR is the rate limiting factor in the activation of IMC/FP59.In addition, staining for Annexin V/PI post IMC/FP59 treatment showed an increase in double positive cells indicating non-apoptotic cell death. …"
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Novel Platinum II and Platinum IV Complexes Exhibit An Anti-Neoplastic Potential Against A549 Cancer Cell Line حسب Baz, Joy

"…Flow cytometry revealed significant cell death by apoptosis and western blots showed the upregulation of intrinsic apoptotic markers. Treatment with Pt II and Pt IV also showed significant amounts of free radical production and increased DNA damage. …"
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Targeting potential arginine auxotrophy in glioblastoma (GBM) cells using human recombinant arginase I (CO)-PEG 5000 [HuArgl (Co)-PEG5000]. (c2013) حسب Khoury, Oula

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Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans حسب Kirti S. Prabhu (4246144)

"…We also found that BTZ exerted its antitumor effects by generating reactive oxygen species (ROS), as blocking ROS production significantly reduced BTZ-induced apoptotic cell death. Interestingly, BTZ treatment induced autophagy, which is evident from the increased expression of microtubule-associated proteins nucleoporin p62 and LC-3A/B. …"