Showing 1 - 20 results of 4,045 for search '(( atp generation decrease ) OR ( a ((large decrease) OR (marked decrease)) ))', query time: 0.52s Refine Results
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    <b>Dihydroxyacetone decreases the dATP pool, inducing replication stress and genomic instability in BEAS-2B cells</b> by Saddam Hussain (22282372)

    Published 2025
    “…DHA exposure reduced ribonucleotide reductase (RRM1/2) expression and specifically depleted dATP pools after 48 h. We confirmed dATP depletion drives replication stress by supplementing cells with adenine during DHA exposure, which decreased DNA lesions, reduced damage signaling, and restored replication. …”
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    Overview of the parameters used in the model. by Albertus Constantijn Sloof (20405090)

    Published 2024
    “…<div><p>Background</p><p>Chikungunya virus (CHIKV) outbreaks, driven by the expanding habitat of the <i>Aedes albopictus</i> mosquito and global climate change, pose a significant threat to public health. Our study evaluates the effectiveness of emergency vaccination using a dynamic disease transmission model for a potential large-scale outbreak in Rome, Italy.…”
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    Mortality rates per lifecycle stage [28]. by Albertus Constantijn Sloof (20405090)

    Published 2024
    “…<div><p>Background</p><p>Chikungunya virus (CHIKV) outbreaks, driven by the expanding habitat of the <i>Aedes albopictus</i> mosquito and global climate change, pose a significant threat to public health. Our study evaluates the effectiveness of emergency vaccination using a dynamic disease transmission model for a potential large-scale outbreak in Rome, Italy.…”
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    <b>The loss of insulin-positive cell clusters precedes the decrease of islet frequency and beta cell area in type 1 diabetes</b> by Denise M. Drotar (21679539)

    Published 2025
    “…Insulin-positive (INS+) single cells (≤10µm), cell clusters (>10 to <35µm), small- and medium-sized islets (35-100µm and 100-200µm) were significantly lost at type 1 diabetes onset, while large INS+ islets (>200µm) were preserved. Moreover, changes in endocrine composition also occurred in mAAb+ donors, including a significant decrease in the INS+ islet fraction. …”