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levels decrease » levels decreased (Expand Search), levels increased (Expand Search), rivers decreased (Expand Search)
marked decrease » marked increase (Expand Search)
large decrease » larger decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
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<b>Dihydroxyacetone decreases the dATP pool, inducing replication stress and genomic instability in BEAS-2B cells</b>
Published 2025“…DHA exposure reduced ribonucleotide reductase (RRM1/2) expression and specifically depleted dATP pools after 48 h. We confirmed dATP depletion drives replication stress by supplementing cells with adenine during DHA exposure, which decreased DNA lesions, reduced damage signaling, and restored replication. …”
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Stereotactic injection of AAV-miR-129-5p suppressed astrocyte activation in depressed mice.
Published 2025Subjects: -
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Stereotactic injection of AAV-miR-129-5p attenuated microglia activation in depressed mice.
Published 2025Subjects: -
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Overexpression of miR-129-5p alleviated depression-like behaviors by increasing ATP content.
Published 2025Subjects: