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a marked » a marker (Expand Search), _ marked (Expand Search), a market (Expand Search)
increase » increased (Expand Search)
a marked » a marker (Expand Search), _ marked (Expand Search), a market (Expand Search)
increase » increased (Expand Search)
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Significantly Enriched Pathways.
Published 2025“…Pathway analysis revealed a marked decrease in expression within certain key metabolic pathways (such as the one-carbon pool by folate) in the NAFLD group, while expression in DNA repair-related pathways (such as non-homologous end joining) was significantly increased. …”
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ALS patients’ tissues exhibit increased phosphorylation of MARK2.
Published 2021“…<p>(<b>A</b>) Representative immunoblot analyses of PKCδ, MARK2-<sup>595</sup>T, and eIF2α in the spinal cord tissues from ALS patients and non-ALS controls, indicating that increased phosphorylation of PKCδ-<sup>505</sup>T, MARK2-<sup>595</sup>T, and eIF2α-<sup>51</sup>S is a general phenotype in patient tissues. …”
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Deletion of Hhp2 markedly increased Sre1 activity.
Published 2020“…<p>Deletion of <i>hhp2</i><sup>+</sup> gene markedly increased Sre1 activity in the presence/absence of CLZ (2 μg/ml to 8 μg/ml) (A), TER (2 μg/ml to 8 μg/ml) (B) or CoCl<sub>2</sub> (0.08 mM to 0.32 mM) (C). …”
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Persistence of β-cell responsiveness for over two years in autoantibody-positive children with marked metabolic impairment at screening
Published 2022“…</p> <p><strong>Results:</strong> Longitudinal analyses revealed annualized AUC C-peptide increases in non-progressors vs. decreases in progressors (p≤0.026 for DPT-1 and TNPTP). …”
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Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis
Published 2022“…In summary, we identify LRIs that mark repressed regions of the genome, and these interactions increase across adipogenesis, pinpointing developmental regions that need to be repressed in a cell-type specific way for adipogenesis to proceed.…”
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Increased phosphorylation of MARK2 occurs in the affected tissues of a mutant SOD1-induced ALS mouse model.
Published 2021“…The staining of phosphorylated MARK2-<sup>595</sup>T in all 3 brain regions is increased in the SOD1<sup>G93A</sup> mice as compared to NTg mice. …”
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