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Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress
Published 2021“…Importantly, SESN2 silencing, unlike thapsigargin, caused a dramatic decrease in protein expression and phosphorylation of Akt, a critical pro-survival hub and component of the AMPK/Akt/mTORC1 axis. …”
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches
Published 2018“…Optimized periodic based manual cleaning with between 5.78% to 28.39% improvement. 4. Periodic based automatic cleaning showed decreases in improvement of between 164.64% to 245.34%. …”
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Zirconium phytate-based proton conductors for high-temperature fuel cell applications
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Wales’ tourists not a burden for local healthcare
Published 2016“…</p><p>“The number of visitors to southwest Wales has increased dramatically over the last ten years, however the number of presentations to the emergency department has not increased at the same rate,” says Battle. …”
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Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice
Published 2015“…Likewise, lung metastasis dramatically increased in the MMTV-PyMT; Mmp8-null mice. …”
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Impact of COVID-19 restrictions on health and well-being in the United Arab Emirates
Published 2023“…Alarmingly, sedentary behavior dramatically increased with 71% of participants spending an average of 4–8 h per day sitting and over 54% of participants spending more than 4 h watching TV on an average day during lockdown. …”
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An End-to-End Concatenated CNN Attention Model for the Classification of Lung Cancer With XAI Techniques
Published 2025“…To address these challenges, an end-to-end concatenated Convolutional Neural Network (CNN) attention model has been proposed for automatic lung cancer classification. This approach integrates two distinct CNNs, followed by a multi-layer perceptron (MLP) and a multi-head attention (MHA) mechanism, to enhance performance. …”
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Spatiotemporal Dynamics of β-Adrenergic cAMP Signals and L-Type Ca2+ Channel Regulation in Adult Rat Ventricular Myocytes
Published 2008“…Inhibition of PDE4 (with 10 μmol/L Ro 20-1724) increased the amplitude and dramatically slowed down the onset and recovery of cAMP signals, whereas PDE3 blockade (with 1 μmol/L cilostamide) had a minor effect only on subsarcolemmal cAMP. …”
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Enhanced differentiation of human pluripotent stem cells into pancreatic progenitors co-expressing PDX1 and NKX6.1
Published 2018“…</p><h3>Results</h3><p dir="ltr">Our optimized protocol dramatically increased the expression of NKX6.1, leading to an increase in the proportion of PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors (~90%) in monolayer, higher than the previously published protocols, as well as upregulated key TFs controlling pancreatic development. …”
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Combined effects of treated domestic wastewater, fly ash, and calcium nitrite toward concrete sustainability
Published 2021“…Test results revealed that TWW slightly decreased concrete compressive and flexural strengths by 5%–12%, whereas it dramatically increased the porosity and chloride permeability by about 40%. …”
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Removal of Ciprofloxacin from Pharmaceutical Wastewater Using White Eggshells as Biosorbents
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Fiber-matrix interfacial area reduction in fiber reinforced cements and concretes at moderate to high fiber volume fractions
Published 2017“…Fiber-fiber interaction and overlap of fibers with fibers, voids and aggregates can dramatically decrease the efficiency of the reinforcement by reducing this interfacial area. …”
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Agent Based Modeling to Optimize Supermarkets Spatial Dimensions
Published 2019“…We solved this problem by providing an optimal area range for the supermarket where we reduced the crowding levels dramatically, while avoiding unnecessary increase in space dimensions. …”
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Genetic biomarkers and machine learning techniques for predicting diabetes: systematic review
Published 2024“…These complications contribute to increased mortality rates, blindness, kidney failure, and an overall diminished quality of life in individuals living with diabetes. …”
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The Impact of Teachers' Opinions of MAP Test on Their Attitude: A Study in a Private School in Dubai
Published 2022“…In addition, Teachers’ questionnaire was utilized as a quantitative instrument to collect data about teachers’ perceptions’ influence on their attitude. The study concluded that teachers’ perceptions heavily affected their attitudes in terms of MAP test data analysis and communicating the automatically generated reports with different stakeholders.…”
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Inequalities in cardiovascular disease among elderly Indians: A gender perspective analysis using LASI wave-I (2017-18)
Published 2024“…Smoking accounted increase in (20.52%) the gender gap while years of schooling dramatically lessened the gender gap (-46.30%). …”
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Advancing Coherent Power Grid Partitioning: A Review Embracing Machine and Deep Learning
Published 2025“…<p dir="ltr">With the escalating intricacy and expansion of the interconnected electrical grid, the likelihood of power system (PS) collapse has escalated dramatically. There is an increased emphasis on immunizing renewable-dominated power systems from large-scale cascading failures and cyberattacks through optimal power grid partitioning (PGP). …”
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A young patient with Graves' disease presenting with a triad of heart failure, pancytopenia, and jaundice: A case report
Published 2024“…We describe a case of a young man who presented with progressive cough, increased abdominal girth and ankle swelling for a few months. …”
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Colon cancer classification using microarray data
Published 2010“…In treating cancer time is of the essence and early detection can dramatically increase the chances of survival. Imaging techniques, which are the prevalent method of detection and diagnosis, are only useful once the cancerous growth has become visible.However, if techniques that detect cancerous processes at a genetic level are utilized then the cancerous tissues could be identified, and the disease diagnosed much earlier, thus giving a far better prognosis.Therefore, the aim of this thesis is to evaluate the performance of a variety of different classification methods with a particular dataset containing genetic samples of both normal and cancerous biopsies of the colon tissue.A classifier will be recommended which is able to learn the patterns within the microarray data that best determines the classification of the samples.…”
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