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701
Supplementary file 1_Exposure-response analyses of venetoclax combined with hypomethylating agents in myelodysplastic syndromes: a retrospective study.docx
Published 2025“…Background<p>Venetoclax (VEN), an orally bioavailable B-cell lymphoma-2 inhibitor, shows promising activity in patients with myelodysplastic syndromes (MDS) when combined with hypomethylating agents (HMAs). …”
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702
Schematic representation of G<sub>1</sub> cell cycle arrest inhibited by CsA in gingival fibroblasts.
Published 2024“…<p>CsA induces the downregulation of SMAD3 and SMAD4, which leads to a decrease in P21. CsA also induces the upregulation of CDC25A, CYCLIN E, phosphorylated CDK2 and phosphorylated RB, which results in the inhibition of G<sub>1</sub> cell cycle arrest. …”
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703
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704
SEAwise Report on Carbon footprint, economic and social impacts of revised management strategies in a changing climate based on information from full MSEs
Published 2025“…In general, CO<sub>2</sub> emissions per kg of fish decreases over time for large-scale fisheries (LSF), but the most negative climate scenarios (related to RCP8.5, NE and WM) are less efficient and yield lower catches. …”
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705
SEAwise report on the impact of socio-economic effects of fisheries management
Published 2025“…Though stocks were expected to recover due to lower fishing mortalities, the effects of climate change on the productivity of cod and saithe had negative consequences on economic performance of both small- and large-scale fleets. As stock productivity declined, revenues from the fishery decreased under stronger warming scenarios, leading to lower employment and higher chances to suffer an income loss. …”
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706
A hypothetical model illustrating the alteration in motility and traction force on a fibronectin-rich substrate during <i>E. histolytica</i> trophozoite migration with and without...
Published 2025“…F-actin primarily accumulates at podosome-like adhesion structures extending downward, which are notably large, elevated and strong, possibly enabling the cells to grip the substrate firmly and effectively. …”
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707
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708
Table 1_Comparative study of endophytic bacterial strains from non-host crops for enhancing plant growth and managing early blight in tomato.docx
Published 2024“…<p>Bacillus pseudomycoides, Paenibacillus polymyxa, and B. velezensis are potent bacterial endophytes, which typically exhibit host-specific interactions. …”
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709
Table 6_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.xlsx
Published 2025“…Furthermore, the highest level of IL1B expression was observed in macrophages in ccRCC samples, and spatial transcriptome analysis revealed the colocalization of VEGFA<sup>+</sup> MCs with IL1B<sup>+</sup> macrophages at the tumor–normal interface.…”
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710
Image 1_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.jpeg
Published 2025“…Furthermore, the highest level of IL1B expression was observed in macrophages in ccRCC samples, and spatial transcriptome analysis revealed the colocalization of VEGFA<sup>+</sup> MCs with IL1B<sup>+</sup> macrophages at the tumor–normal interface.…”
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711
Table 1_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.xlsx
Published 2025“…Furthermore, the highest level of IL1B expression was observed in macrophages in ccRCC samples, and spatial transcriptome analysis revealed the colocalization of VEGFA<sup>+</sup> MCs with IL1B<sup>+</sup> macrophages at the tumor–normal interface.…”
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712
Image 4_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.jpeg
Published 2025“…Furthermore, the highest level of IL1B expression was observed in macrophages in ccRCC samples, and spatial transcriptome analysis revealed the colocalization of VEGFA<sup>+</sup> MCs with IL1B<sup>+</sup> macrophages at the tumor–normal interface.…”
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713
Table 7_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.xlsx
Published 2025“…Furthermore, the highest level of IL1B expression was observed in macrophages in ccRCC samples, and spatial transcriptome analysis revealed the colocalization of VEGFA<sup>+</sup> MCs with IL1B<sup>+</sup> macrophages at the tumor–normal interface.…”
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714
Table 4_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.xlsx
Published 2025“…Furthermore, the highest level of IL1B expression was observed in macrophages in ccRCC samples, and spatial transcriptome analysis revealed the colocalization of VEGFA<sup>+</sup> MCs with IL1B<sup>+</sup> macrophages at the tumor–normal interface.…”
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715
Table 5_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.xlsx
Published 2025“…Furthermore, the highest level of IL1B expression was observed in macrophages in ccRCC samples, and spatial transcriptome analysis revealed the colocalization of VEGFA<sup>+</sup> MCs with IL1B<sup>+</sup> macrophages at the tumor–normal interface.…”
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716
Table 2_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.xlsx
Published 2025“…Furthermore, the highest level of IL1B expression was observed in macrophages in ccRCC samples, and spatial transcriptome analysis revealed the colocalization of VEGFA<sup>+</sup> MCs with IL1B<sup>+</sup> macrophages at the tumor–normal interface.…”
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717
Image 3_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.jpeg
Published 2025“…Furthermore, the highest level of IL1B expression was observed in macrophages in ccRCC samples, and spatial transcriptome analysis revealed the colocalization of VEGFA<sup>+</sup> MCs with IL1B<sup>+</sup> macrophages at the tumor–normal interface.…”
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718
Image 5_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.jpeg
Published 2025“…Furthermore, the highest level of IL1B expression was observed in macrophages in ccRCC samples, and spatial transcriptome analysis revealed the colocalization of VEGFA<sup>+</sup> MCs with IL1B<sup>+</sup> macrophages at the tumor–normal interface.…”
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719
Table 3_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.xlsx
Published 2025“…Furthermore, the highest level of IL1B expression was observed in macrophages in ccRCC samples, and spatial transcriptome analysis revealed the colocalization of VEGFA<sup>+</sup> MCs with IL1B<sup>+</sup> macrophages at the tumor–normal interface.…”
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720
Table 9_Single-cell transcriptomics reveals the heterogeneity and function of mast cells in human ccRCC.xlsx
Published 2025“…Furthermore, the highest level of IL1B expression was observed in macrophages in ccRCC samples, and spatial transcriptome analysis revealed the colocalization of VEGFA<sup>+</sup> MCs with IL1B<sup>+</sup> macrophages at the tumor–normal interface.…”