Search alternatives:
marked decrease » marked increase (Expand Search)
large decrease » larger decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
b marked » _ marked (Expand Search), a marked (Expand Search), n marked (Expand Search)
c large » _ large (Expand Search), a large (Expand Search), b large (Expand Search)
marked decrease » marked increase (Expand Search)
large decrease » larger decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
b marked » _ marked (Expand Search), a marked (Expand Search), n marked (Expand Search)
c large » _ large (Expand Search), a large (Expand Search), b large (Expand Search)
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<b>Effect of Marked Weight Loss on Adipose Tissue Biology in People with Obesity and Type 2 Diabetes</b>
Published 2025“…</p><p dir="ltr"><b>Results: </b>Weight loss: <a href="" target="_blank">i) </a><a href="" target="_blank">decreased adipose tissue </a>expression of genes related to extracellular matrix remodeling; ii) decreased adipose tissue expression of SERPINE 1 which encodes plasminogen activator inhibitor-1 (PAI-1); iii) did not decrease adipose tissue immune cell content or expression of genes involved in inflammation; iv) decreased adipose tissue ceramide content; v) decreased plasma <a href="" target="_blank">PAI-1 </a>and leptin concentrations and increased plasma high-molecular weight (HMW) adiponectin; and vi) decreased plasma small extracellular vesicle (sEV) concentration and the sEV content of microRNAs proposed to inhibit insulin action, and completely reversed the inhibitory effect of plasma sEVs on insulin signaling in myotubes.…”
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ROC analysis to mark selectivity results in mostly mixed-selective units.
Published 2025“…The large number of mixed selective units also results in a significant decrease in accuracy when these neurons are targeted as compared to <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1013559#pcbi.1013559.g006" target="_blank">Fig 6c</a> where there was no significant effect visible after targeting mixed selective units, likely because there were less mixed selective units present. …”
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