بدائل البحث:
action optimization » reaction optimization (توسيع البحث), function optimization (توسيع البحث), codon optimization (توسيع البحث)
guided optimization » based optimization (توسيع البحث), model optimization (توسيع البحث)
binary based » library based (توسيع البحث), linac based (توسيع البحث), binary mask (توسيع البحث)
based action » based motion (توسيع البحث), based active (توسيع البحث), based fusion (توسيع البحث)
action optimization » reaction optimization (توسيع البحث), function optimization (توسيع البحث), codon optimization (توسيع البحث)
guided optimization » based optimization (توسيع البحث), model optimization (توسيع البحث)
binary based » library based (توسيع البحث), linac based (توسيع البحث), binary mask (توسيع البحث)
based action » based motion (توسيع البحث), based active (توسيع البحث), based fusion (توسيع البحث)
-
1
Table 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf
منشور في 2025"…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …"
-
2
Presentation 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf
منشور في 2025"…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …"
-
3
Table 2_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf
منشور في 2025"…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …"
-
4
Image 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.png
منشور في 2025"…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …"
-
5
Image 2_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.png
منشور في 2025"…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …"
-
6
MultiCRISPR-EGA: Optimizing Guide RNA Array Design for Multiplexed CRISPR Using the Elitist Genetic Algorithm
منشور في 2025"…Computational experiments on Escherichia coli gene targets demonstrate that the EGA can rapidly optimize multiplexed gRNA arrays, outperforming other intelligent optimization algorithms in CRISPR interference (CRISPRi) applications, while the GUI provides real-time design progress control and compatibility with various CRISPR-Cas systems. …"
-
7
-
8
-
9
Raw Data for the Thesis: "<i>Enhancing RNAi-Based Pest Control through Effective Target Gene Selection and Optimal dsRNA Design</i>"
منشور في 2025"…The results revealed moderate transferability (~50%) of highly effective targets from <i>T. castaneum</i>, which increased to approximately 80% when considering genes already validated in other leaf beetles. These findings are both conceptually important, in demonstrating partial but significant cross-species transferability of RNAi targets, and practically valuable for guiding the development of RNAi-based solutions against this important pest.…"
-
10
<i>OptRAM</i>: <i>In-silico</i> strain design via integrative regulatory-metabolic network modeling
منشور في 2019"…To address challenges in metabolic engineering, computational strain optimization algorithms based on genome-scale metabolic models have increasingly been used to aid in overproducing products of interest. …"
-
11
-
12
-
13
Table1_Study of PARP inhibitors for breast cancer based on enhanced multiple kernel function SVR with PSO.docx
منشور في 2024"…The problem of multi-parameter optimization introduced in the support vector regression model was solved by the particle swarm optimization algorithm. …"
-
14
Table1_Identification of Immune-Related Genes for Risk Stratification in Multiple Myeloma Based on Whole Bone Marrow Gene Expression Profiling.XLSX
منشور في 2022"…Tumor immunotherapy, a new therapy that has emerged in recent years, offers hope to patients, and studying the expression characteristics of immune-related genes (IRGs) based on whole bone marrow gene expression profiling (GEP) in MM patients can help guide personalized immunotherapy.…"
-
15
Image2_Identification of Immune-Related Genes for Risk Stratification in Multiple Myeloma Based on Whole Bone Marrow Gene Expression Profiling.TIFF
منشور في 2022"…Tumor immunotherapy, a new therapy that has emerged in recent years, offers hope to patients, and studying the expression characteristics of immune-related genes (IRGs) based on whole bone marrow gene expression profiling (GEP) in MM patients can help guide personalized immunotherapy.…"
-
16
Image1_Identification of Immune-Related Genes for Risk Stratification in Multiple Myeloma Based on Whole Bone Marrow Gene Expression Profiling.TIFF
منشور في 2022"…Tumor immunotherapy, a new therapy that has emerged in recent years, offers hope to patients, and studying the expression characteristics of immune-related genes (IRGs) based on whole bone marrow gene expression profiling (GEP) in MM patients can help guide personalized immunotherapy.…"
-
17
-
18
DataSheet1_Study of PARP inhibitors for breast cancer based on enhanced multiple kernel function SVR with PSO.ZIP
منشور في 2024"…The problem of multi-parameter optimization introduced in the support vector regression model was solved by the particle swarm optimization algorithm. …"
-
19
-
20
Data Sheet 1_Clinical potential and experimental validation of prognostic genes in hepatocellular carcinoma revealed by risk modeling utilizing single cell and transcriptome constr...
منشور في 2025"…</p>Methods<p>The HCC datasets were obtained from public databases and then differential expression analysis were used to obtain significant gene expression profiles. Subsequently, univariate Cox regression analysis and PH assumption test were performed, and a risk model was developed using an optimal algorithm from 101 combinations on the TCGA-LIHC dataset to pinpoint prognostic genes. …"