Search alternatives:
active optimization » acid optimization (Expand Search), objective optimization (Expand Search), reaction optimization (Expand Search)
guided optimization » based optimization (Expand Search), model optimization (Expand Search)
binary based » library based (Expand Search), linac based (Expand Search), binary mask (Expand Search)
based active » based practice (Expand Search), based activity (Expand Search)
genes based » gene based (Expand Search), lens based (Expand Search)
active optimization » acid optimization (Expand Search), objective optimization (Expand Search), reaction optimization (Expand Search)
guided optimization » based optimization (Expand Search), model optimization (Expand Search)
binary based » library based (Expand Search), linac based (Expand Search), binary mask (Expand Search)
based active » based practice (Expand Search), based activity (Expand Search)
genes based » gene based (Expand Search), lens based (Expand Search)
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Table 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf
Published 2025“…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …”
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Presentation 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf
Published 2025“…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …”
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Table 2_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.pdf
Published 2025“…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …”
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Image 1_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.png
Published 2025“…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …”
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Image 2_A computational framework for optimizing mRNA vaccine delivery via AI-guided nanoparticle design and in silico gene expression profiling.png
Published 2025“…Differential gene expression analysis identified compartment-specific transcriptional responses, which were then used to construct a risk index based on predicted immune activation and the number of upregulated immune markers. …”
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Python-Based Algorithm for Estimating NRTL Model Parameters with UNIFAC Model Simulation Results
Published 2025Subjects: -
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MultiCRISPR-EGA: Optimizing Guide RNA Array Design for Multiplexed CRISPR Using the Elitist Genetic Algorithm
Published 2025“…Computational experiments on Escherichia coli gene targets demonstrate that the EGA can rapidly optimize multiplexed gRNA arrays, outperforming other intelligent optimization algorithms in CRISPR interference (CRISPRi) applications, while the GUI provides real-time design progress control and compatibility with various CRISPR-Cas systems. …”
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QSAR model for predicting neuraminidase inhibitors of influenza A viruses (H1N1) based on adaptive grasshopper optimization algorithm
Published 2020“…The binary grasshopper optimization algorithm (BGOA) is a new meta-heuristic optimization algorithm, which has been used successfully to perform feature selection. …”
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<i>OptRAM</i>: <i>In-silico</i> strain design via integrative regulatory-metabolic network modeling
Published 2019“…To address challenges in metabolic engineering, computational strain optimization algorithms based on genome-scale metabolic models have increasingly been used to aid in overproducing products of interest. …”
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Raw Data for the Thesis: "<i>Enhancing RNAi-Based Pest Control through Effective Target Gene Selection and Optimal dsRNA Design</i>"
Published 2025“…The results revealed moderate transferability (~50%) of highly effective targets from <i>T. castaneum</i>, which increased to approximately 80% when considering genes already validated in other leaf beetles. These findings are both conceptually important, in demonstrating partial but significant cross-species transferability of RNAi targets, and practically valuable for guiding the development of RNAi-based solutions against this important pest.…”
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Data_Sheet_1_A real-time driver fatigue identification method based on GA-GRNN.ZIP
Published 2022“…<p>It is of great practical and theoretical significance to identify driver fatigue state in real time and accurately and provide active safety warning in time. In this paper, a non-invasive and low-cost method of fatigue driving state identification based on genetic algorithm optimization of generalized regression neural network model is proposed. …”
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Data Sheet 1_Clinical potential and experimental validation of prognostic genes in hepatocellular carcinoma revealed by risk modeling utilizing single cell and transcriptome constr...
Published 2025“…</p>Methods<p>The HCC datasets were obtained from public databases and then differential expression analysis were used to obtain significant gene expression profiles. Subsequently, univariate Cox regression analysis and PH assumption test were performed, and a risk model was developed using an optimal algorithm from 101 combinations on the TCGA-LIHC dataset to pinpoint prognostic genes. …”
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Table1_Identification of Immune-Related Genes for Risk Stratification in Multiple Myeloma Based on Whole Bone Marrow Gene Expression Profiling.XLSX
Published 2022“…Tumor immunotherapy, a new therapy that has emerged in recent years, offers hope to patients, and studying the expression characteristics of immune-related genes (IRGs) based on whole bone marrow gene expression profiling (GEP) in MM patients can help guide personalized immunotherapy.…”
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Image2_Identification of Immune-Related Genes for Risk Stratification in Multiple Myeloma Based on Whole Bone Marrow Gene Expression Profiling.TIFF
Published 2022“…Tumor immunotherapy, a new therapy that has emerged in recent years, offers hope to patients, and studying the expression characteristics of immune-related genes (IRGs) based on whole bone marrow gene expression profiling (GEP) in MM patients can help guide personalized immunotherapy.…”
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Image1_Identification of Immune-Related Genes for Risk Stratification in Multiple Myeloma Based on Whole Bone Marrow Gene Expression Profiling.TIFF
Published 2022“…Tumor immunotherapy, a new therapy that has emerged in recent years, offers hope to patients, and studying the expression characteristics of immune-related genes (IRGs) based on whole bone marrow gene expression profiling (GEP) in MM patients can help guide personalized immunotherapy.…”
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Table1_Study of PARP inhibitors for breast cancer based on enhanced multiple kernel function SVR with PSO.docx
Published 2024“…The problem of multi-parameter optimization introduced in the support vector regression model was solved by the particle swarm optimization algorithm. …”