بدائل البحث:
function optimization » reaction optimization (توسيع البحث), formulation optimization (توسيع البحث), generation optimization (توسيع البحث)
cell optimization » field optimization (توسيع البحث), wolf optimization (توسيع البحث), lead optimization (توسيع البحث)
based function » based functional (توسيع البحث), basis function (توسيع البحث), basis functions (توسيع البحث)
binary based » library based (توسيع البحث), linac based (توسيع البحث), binary mask (توسيع البحث)
function optimization » reaction optimization (توسيع البحث), formulation optimization (توسيع البحث), generation optimization (توسيع البحث)
cell optimization » field optimization (توسيع البحث), wolf optimization (توسيع البحث), lead optimization (توسيع البحث)
based function » based functional (توسيع البحث), basis function (توسيع البحث), basis functions (توسيع البحث)
binary based » library based (توسيع البحث), linac based (توسيع البحث), binary mask (توسيع البحث)
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Stochastic simulation and statistical inference platform for visualization and estimation of transcriptional kinetics
منشور في 2020"…As a demonstration, we show that the optimization algorithm can successfully recover the transcriptional kinetics of simulated and experimental gene expression data. …"
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66
<i>OptRAM</i>: <i>In-silico</i> strain design via integrative regulatory-metabolic network modeling
منشور في 2019"…To address challenges in metabolic engineering, computational strain optimization algorithms based on genome-scale metabolic models have increasingly been used to aid in overproducing products of interest. …"
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Raw Data for the Thesis: "<i>Enhancing RNAi-Based Pest Control through Effective Target Gene Selection and Optimal dsRNA Design</i>"
منشور في 2025"…</p><p><br></p><p dir="ltr">Chapter 4 introduces the dsRIP web platform (<a href="https://dsrip.uni-goettingen.de/" target="_blank">https://dsrip.uni-goettingen.de/</a>) for designing sequence-optimized dsRNA for RNAi-based pest control. In the experimental part, small interfering RNA (siRNA) features that were associated with RNAi efficacy in human cells were tested in <i>T. castaneum </i>by targeting an essential gene and measuring insecticidal efficacy. …"
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69
DataSheet_1_Trans-population graph-based coverage optimization of allogeneic cellular therapy.xlsx
منشور في 2023"…We propose here a solution to this problem, and test whether it would be more expensive to recruit additional donors or to prevent class I or class II HLA expression through gene editing.</p>Study design<p>We developed an optimal coverage problem, combined with a graph-based algorithm to solve the donor selection problem under different, clinically plausible scenarios (having different HLA matching priorities). …"
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70
DataSheet_1_Trans-population graph-based coverage optimization of allogeneic cellular therapy.xlsx
منشور في 2023"…We propose here a solution to this problem, and test whether it would be more expensive to recruit additional donors or to prevent class I or class II HLA expression through gene editing.</p>Study design<p>We developed an optimal coverage problem, combined with a graph-based algorithm to solve the donor selection problem under different, clinically plausible scenarios (having different HLA matching priorities). …"
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71
DataSheet_1_Trans-population graph-based coverage optimization of allogeneic cellular therapy.xlsx
منشور في 2023"…We propose here a solution to this problem, and test whether it would be more expensive to recruit additional donors or to prevent class I or class II HLA expression through gene editing.</p>Study design<p>We developed an optimal coverage problem, combined with a graph-based algorithm to solve the donor selection problem under different, clinically plausible scenarios (having different HLA matching priorities). …"
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Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures
منشور في 2023الموضوعات: -
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Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures
منشور في 2023الموضوعات: -
75
Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures
منشور في 2023الموضوعات: -
76
Table 1_Identification of immunogenic cell death signature genes in hepatocellular carcinoma: from single-cell transcriptomics to in vitro mechanistic validation and comprehensive...
منشور في 2025"…We identified HCC-specific ICD-related (HCC-ICDR) genes via WGCNA and optimized a prognostic model by benchmarking machine learning algorithms. …"
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Table_1_One-Time Optimization of Advanced T Cell Culture Media Using a Machine Learning Pipeline.DOCX
منشور في 2021"…<p>The growing application of cell and gene therapies in humans leads to a need for cell type-optimized culture media. …"
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Data Sheet 1_Identification of immunogenic cell death signature genes in hepatocellular carcinoma: from single-cell transcriptomics to in vitro mechanistic validation and comprehen...
منشور في 2025"…We identified HCC-specific ICD-related (HCC-ICDR) genes via WGCNA and optimized a prognostic model by benchmarking machine learning algorithms. …"