Search alternatives:
method optimization » lead optimization (Expand Search), path optimization (Expand Search), feature optimization (Expand Search)
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based method » based methods (Expand Search)
genes based » gene based (Expand Search), lens based (Expand Search)
based small » based smart (Expand Search), based sample (Expand Search)
method optimization » lead optimization (Expand Search), path optimization (Expand Search), feature optimization (Expand Search)
small optimization » swarm optimization (Expand Search), whale optimization (Expand Search), spatial optimization (Expand Search)
binary based » library based (Expand Search), linac based (Expand Search), binary mask (Expand Search)
based method » based methods (Expand Search)
genes based » gene based (Expand Search), lens based (Expand Search)
based small » based smart (Expand Search), based sample (Expand Search)
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102
Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures
Published 2023“…Recent advances in accessibility of open-source drug-induced transcriptomic data along with the ability of deep learning algorithms to understand hidden patterns have opened opportunities for designing drug molecules based on desired gene expression signatures. …”
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103
Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures
Published 2023“…Recent advances in accessibility of open-source drug-induced transcriptomic data along with the ability of deep learning algorithms to understand hidden patterns have opened opportunities for designing drug molecules based on desired gene expression signatures. …”
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104
Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures
Published 2023“…Recent advances in accessibility of open-source drug-induced transcriptomic data along with the ability of deep learning algorithms to understand hidden patterns have opened opportunities for designing drug molecules based on desired gene expression signatures. …”
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105
DataSheet_1_Trans-population graph-based coverage optimization of allogeneic cellular therapy.xlsx
Published 2023“…We propose here a solution to this problem, and test whether it would be more expensive to recruit additional donors or to prevent class I or class II HLA expression through gene editing.</p>Study design<p>We developed an optimal coverage problem, combined with a graph-based algorithm to solve the donor selection problem under different, clinically plausible scenarios (having different HLA matching priorities). …”
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106
DataSheet_1_Trans-population graph-based coverage optimization of allogeneic cellular therapy.xlsx
Published 2023“…We propose here a solution to this problem, and test whether it would be more expensive to recruit additional donors or to prevent class I or class II HLA expression through gene editing.</p>Study design<p>We developed an optimal coverage problem, combined with a graph-based algorithm to solve the donor selection problem under different, clinically plausible scenarios (having different HLA matching priorities). …”
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107
DataSheet_1_Trans-population graph-based coverage optimization of allogeneic cellular therapy.xlsx
Published 2023“…We propose here a solution to this problem, and test whether it would be more expensive to recruit additional donors or to prevent class I or class II HLA expression through gene editing.</p>Study design<p>We developed an optimal coverage problem, combined with a graph-based algorithm to solve the donor selection problem under different, clinically plausible scenarios (having different HLA matching priorities). …”
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108
Design and implementation of the Multiple Criteria Decision Making (MCDM) algorithm for predicting the severity of COVID-19.
Published 2021“…<p>(A). The MCDM algorithm-Stage 1. Preprocessing, this stage is the process of refining the collected raw data to eliminate noise, including correlation analysis and feature selection based on P values. …”
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109
Data_Sheet_3_Deciphering the Subtype Differentiation History of SARS-CoV-2 Based on a New Breadth-First Searching Optimized Alignment Method Over a Global Data Set of 24,768 Sequen...
Published 2021“…Existing research on coronavirus mutations is based on small data sets, and multiple sequence alignment using a global-scale data set has yet to be conducted. …”
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110
Data_Sheet_4_Deciphering the Subtype Differentiation History of SARS-CoV-2 Based on a New Breadth-First Searching Optimized Alignment Method Over a Global Data Set of 24,768 Sequen...
Published 2021“…Existing research on coronavirus mutations is based on small data sets, and multiple sequence alignment using a global-scale data set has yet to be conducted. …”
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111
Data_Sheet_2_Deciphering the Subtype Differentiation History of SARS-CoV-2 Based on a New Breadth-First Searching Optimized Alignment Method Over a Global Data Set of 24,768 Sequen...
Published 2021“…Existing research on coronavirus mutations is based on small data sets, and multiple sequence alignment using a global-scale data set has yet to be conducted. …”
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112
Data_Sheet_1_Deciphering the Subtype Differentiation History of SARS-CoV-2 Based on a New Breadth-First Searching Optimized Alignment Method Over a Global Data Set of 24,768 Sequen...
Published 2021“…Existing research on coronavirus mutations is based on small data sets, and multiple sequence alignment using a global-scale data set has yet to be conducted. …”
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113
Data_Sheet_6_Deciphering the Subtype Differentiation History of SARS-CoV-2 Based on a New Breadth-First Searching Optimized Alignment Method Over a Global Data Set of 24,768 Sequen...
Published 2021“…Existing research on coronavirus mutations is based on small data sets, and multiple sequence alignment using a global-scale data set has yet to be conducted. …”
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114
Data_Sheet_5_Deciphering the Subtype Differentiation History of SARS-CoV-2 Based on a New Breadth-First Searching Optimized Alignment Method Over a Global Data Set of 24,768 Sequen...
Published 2021“…Existing research on coronavirus mutations is based on small data sets, and multiple sequence alignment using a global-scale data set has yet to be conducted. …”
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115
Triplet Matching for Estimating Causal Effects With Three Treatment Arms: A Comparative Study of Mortality by Trauma Center Level
Published 2021“…We implement the evidence factors method for binary outcomes, which includes a randomization-based testing strategy and a sensitivity analysis for hidden bias in three-group matched designs. …”
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116
Flowchart scheme of the ML-based model.
Published 2024“…<b>I)</b> Testing data consisting of 20% of the entire dataset. <b>J)</b> Optimization of hyperparameter tuning. <b>K)</b> Algorithm selection from all models. …”
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117
Image_3_Comprehensive NGS profiling to enable detection of ALK gene rearrangements and MET amplifications in non-small cell lung cancer.jpeg
Published 2023“…</p>Methods<p>There were 12 ALK rearrangement-positive tumor specimens from patients with non-small cell lung cancer (NSCLC) previously detected via fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), and an RNA-based NGS assay, and 26 MET high gene copy number (GCN) cases detected by FISH, selected for this retrospective study. …”
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118
Image_2_Comprehensive NGS profiling to enable detection of ALK gene rearrangements and MET amplifications in non-small cell lung cancer.jpeg
Published 2023“…</p>Methods<p>There were 12 ALK rearrangement-positive tumor specimens from patients with non-small cell lung cancer (NSCLC) previously detected via fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), and an RNA-based NGS assay, and 26 MET high gene copy number (GCN) cases detected by FISH, selected for this retrospective study. …”
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119
Table_1_Comprehensive NGS profiling to enable detection of ALK gene rearrangements and MET amplifications in non-small cell lung cancer.docx
Published 2023“…</p>Methods<p>There were 12 ALK rearrangement-positive tumor specimens from patients with non-small cell lung cancer (NSCLC) previously detected via fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), and an RNA-based NGS assay, and 26 MET high gene copy number (GCN) cases detected by FISH, selected for this retrospective study. …”
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120
Image_1_Comprehensive NGS profiling to enable detection of ALK gene rearrangements and MET amplifications in non-small cell lung cancer.jpeg
Published 2023“…</p>Methods<p>There were 12 ALK rearrangement-positive tumor specimens from patients with non-small cell lung cancer (NSCLC) previously detected via fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), and an RNA-based NGS assay, and 26 MET high gene copy number (GCN) cases detected by FISH, selected for this retrospective study. …”