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process optimization » model optimization (Expand Search)
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process optimization » model optimization (Expand Search)
cell optimization » field optimization (Expand Search), wolf optimization (Expand Search), lead optimization (Expand Search)
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161
Data Sheet 4_Identification of a signature gene set for oxaliplatin sensitivity prediction in colorectal cancer.pdf
Published 2025“…Finally, we experimentally assessed the functional role of these genes by examining their expression in oxaliplatin-resistant cell lines and by performing gene knockdown experiments in colorectal cancer cells to measure subsequent changes in oxaliplatin sensitivity.…”
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162
Data Sheet 1_Identification of a signature gene set for oxaliplatin sensitivity prediction in colorectal cancer.pdf
Published 2025“…Finally, we experimentally assessed the functional role of these genes by examining their expression in oxaliplatin-resistant cell lines and by performing gene knockdown experiments in colorectal cancer cells to measure subsequent changes in oxaliplatin sensitivity.…”
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163
Table 1_Identification of a signature gene set for oxaliplatin sensitivity prediction in colorectal cancer.xlsx
Published 2025“…Finally, we experimentally assessed the functional role of these genes by examining their expression in oxaliplatin-resistant cell lines and by performing gene knockdown experiments in colorectal cancer cells to measure subsequent changes in oxaliplatin sensitivity.…”
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164
Data Sheet 2_Identification of a signature gene set for oxaliplatin sensitivity prediction in colorectal cancer.pdf
Published 2025“…Finally, we experimentally assessed the functional role of these genes by examining their expression in oxaliplatin-resistant cell lines and by performing gene knockdown experiments in colorectal cancer cells to measure subsequent changes in oxaliplatin sensitivity.…”
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165
Image 1_Identification of a signature gene set for oxaliplatin sensitivity prediction in colorectal cancer.pdf
Published 2025“…Finally, we experimentally assessed the functional role of these genes by examining their expression in oxaliplatin-resistant cell lines and by performing gene knockdown experiments in colorectal cancer cells to measure subsequent changes in oxaliplatin sensitivity.…”
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166
Data Sheet 3_Identification of a signature gene set for oxaliplatin sensitivity prediction in colorectal cancer.pdf
Published 2025“…Finally, we experimentally assessed the functional role of these genes by examining their expression in oxaliplatin-resistant cell lines and by performing gene knockdown experiments in colorectal cancer cells to measure subsequent changes in oxaliplatin sensitivity.…”
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170
Methodology block diagram.
Published 2025“…Six machine learning algorithms - Random Forest (RF), AdaBoost, Light Gradient Boosting Machine (LightGBM), eXtreme Gradient Boosting (XGBoost), Categorical Boosting (CatBoost), and Tabular Prior-data Fitted Network version 2.0 (TabPFN-V2) - were implemented with five-fold cross-validation to optimize model hyperparameters. …”
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171
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172
DataSheet_1_Computational identification and clinical validation of a novel risk signature based on coagulation-related lncRNAs for predicting prognosis, immunotherapy response, an...
Published 2023“…</p>Methods<p>CRC samples from The Cancer Genome Atlas (TCGA) were used as the training set, while the substantial bulk or single-cell RNA transcriptomics from Gene Expression Omnibus (GEO) datasets and real-time quantitative PCR (RT-qPCR) data from CRC cell lines and paired frozen tissues were used for validation. …”
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173
Table 1_Developing and validating a drug recommendation system based on tumor microenvironment and drug fingerprint.xlsx
Published 2025“…This study aimed to develop a personalized drug recommendation model leveraging genomic profiles to optimize therapeutic outcomes.</p>Methods<p>A content-based filtering algorithm was implemented to predict drug sensitivity. …”
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174
Table 2_Developing and validating a drug recommendation system based on tumor microenvironment and drug fingerprint.xlsx
Published 2025“…This study aimed to develop a personalized drug recommendation model leveraging genomic profiles to optimize therapeutic outcomes.</p>Methods<p>A content-based filtering algorithm was implemented to predict drug sensitivity. …”
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175
Table 3_Developing and validating a drug recommendation system based on tumor microenvironment and drug fingerprint.xlsx
Published 2025“…This study aimed to develop a personalized drug recommendation model leveraging genomic profiles to optimize therapeutic outcomes.</p>Methods<p>A content-based filtering algorithm was implemented to predict drug sensitivity. …”
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176
Image 4_Integrated machine learning analysis of 30 cell death patterns identifies a novel prognostic signature in glioma.jpeg
Published 2025“…A pan-death prognostic signature (Cell-Death Score, CDS), constructed via multi-algorithm machine learning and optimized using CoxBoost to incorporate 25 key genes, demonstrated robust performance in training (1-/3-year AUC = 0.894/0.943) and validation cohort (C-index = 0.717), effectively stratifying high-risk patients (HR = 3.21, p < 0.0001). …”
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177
Table 2_Integrated machine learning analysis of 30 cell death patterns identifies a novel prognostic signature in glioma.xlsx
Published 2025“…A pan-death prognostic signature (Cell-Death Score, CDS), constructed via multi-algorithm machine learning and optimized using CoxBoost to incorporate 25 key genes, demonstrated robust performance in training (1-/3-year AUC = 0.894/0.943) and validation cohort (C-index = 0.717), effectively stratifying high-risk patients (HR = 3.21, p < 0.0001). …”
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178
Table 1_Integrated machine learning analysis of 30 cell death patterns identifies a novel prognostic signature in glioma.xlsx
Published 2025“…A pan-death prognostic signature (Cell-Death Score, CDS), constructed via multi-algorithm machine learning and optimized using CoxBoost to incorporate 25 key genes, demonstrated robust performance in training (1-/3-year AUC = 0.894/0.943) and validation cohort (C-index = 0.717), effectively stratifying high-risk patients (HR = 3.21, p < 0.0001). …”
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179
Image 3_Integrated machine learning analysis of 30 cell death patterns identifies a novel prognostic signature in glioma.jpeg
Published 2025“…A pan-death prognostic signature (Cell-Death Score, CDS), constructed via multi-algorithm machine learning and optimized using CoxBoost to incorporate 25 key genes, demonstrated robust performance in training (1-/3-year AUC = 0.894/0.943) and validation cohort (C-index = 0.717), effectively stratifying high-risk patients (HR = 3.21, p < 0.0001). …”
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180
Image 2_Integrated machine learning analysis of 30 cell death patterns identifies a novel prognostic signature in glioma.jpeg
Published 2025“…A pan-death prognostic signature (Cell-Death Score, CDS), constructed via multi-algorithm machine learning and optimized using CoxBoost to incorporate 25 key genes, demonstrated robust performance in training (1-/3-year AUC = 0.894/0.943) and validation cohort (C-index = 0.717), effectively stratifying high-risk patients (HR = 3.21, p < 0.0001). …”