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    Supplementary Material for: Penalized Logistic Regression Analysis for Genetic Association Studies of Binary Phenotypes by Yu Y. (3096192)

    Published 2022
    “…We consider two approximate approaches to maximizing the marginal likelihood: (i) a Monte Carlo EM algorithm (MCEM) and (ii) a Laplace approximation (LA) to each integral, followed by derivative-free optimization of the approximation. …”