Search alternatives:
action optimization » reaction optimization (Expand Search), function optimization (Expand Search), codon optimization (Expand Search)
based optimization » whale optimization (Expand Search)
based action » based motion (Expand Search), based active (Expand Search), based fusion (Expand Search)
genes based » gene based (Expand Search), lens based (Expand Search)
action optimization » reaction optimization (Expand Search), function optimization (Expand Search), codon optimization (Expand Search)
based optimization » whale optimization (Expand Search)
based action » based motion (Expand Search), based active (Expand Search), based fusion (Expand Search)
genes based » gene based (Expand Search), lens based (Expand Search)
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Raw Data for the Thesis: "<i>Enhancing RNAi-Based Pest Control through Effective Target Gene Selection and Optimal dsRNA Design</i>"
Published 2025“…</p><p><br></p><p dir="ltr">Chapter 4 introduces the dsRIP web platform (<a href="https://dsrip.uni-goettingen.de/" target="_blank">https://dsrip.uni-goettingen.de/</a>) for designing sequence-optimized dsRNA for RNAi-based pest control. In the experimental part, small interfering RNA (siRNA) features that were associated with RNAi efficacy in human cells were tested in <i>T. castaneum </i>by targeting an essential gene and measuring insecticidal efficacy. …”
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<i>hi</i>PRS algorithm process flow.
Published 2023“…From this dataset we can compute the MI between each interaction and the outcome and <b>(D)</b> obtain a ranked list (<i>I</i><sub><i>δ</i></sub>) based on this metric. …”
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Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures
Published 2023“…Most importantly, this knowledge can be used to discover drugs’ mechanisms of action. Recently, deep learning-based drug design methods are in the spotlight due to their ability to explore huge chemical space and design property-optimized target-specific drug molecules. …”
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Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures
Published 2023“…Most importantly, this knowledge can be used to discover drugs’ mechanisms of action. Recently, deep learning-based drug design methods are in the spotlight due to their ability to explore huge chemical space and design property-optimized target-specific drug molecules. …”
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Gex2SGen: Designing Drug-like Molecules from Desired Gene Expression Signatures
Published 2023“…Most importantly, this knowledge can be used to discover drugs’ mechanisms of action. Recently, deep learning-based drug design methods are in the spotlight due to their ability to explore huge chemical space and design property-optimized target-specific drug molecules. …”
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Design and implementation of the Multiple Criteria Decision Making (MCDM) algorithm for predicting the severity of COVID-19.
Published 2021“…P <0.05 was considered statistically significant. (B). The MCDM algorithm-Stage 2. Feature Ranking, this stage is the process of using the TOPSIS method to rank features. …”
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DataSheet_1_Machine Learning Uses Chemo-Transcriptomic Profiles to Stratify Antimalarial Compounds With Similar Mode of Action.pdf
Published 2021“…<p>The rapid development of antimalarial resistance motivates the continued search for novel compounds with a mode of action (MoA) different to current antimalarials. Phenotypic screening has delivered thousands of promising hit compounds without prior knowledge of the compounds’ exact target or MoA. …”
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DataSheet1_Revealing the novel ferroptosis-related therapeutic targets for diabetic foot ulcer based on the machine learning.zip
Published 2022“…Eventually, an optimal DFU prediction model was created by combining multiple machine learning algorithms (LASSO, SVM-RFE, Boruta, and XGBoost) to detect ferroposis genes most closely associated with DFU. …”
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Data_Sheet_1_Prediction of Mental Health in Medical Workers During COVID-19 Based on Machine Learning.ZIP
Published 2021“…In this study, we propose a novel prediction model based on optimization algorithm and neural network, which can select and rank the most important factors that affect mental health of medical workers. …”
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Table 1_Plasma exosomal lncRNA-related signatures define molecular subtypes and predict survival and treatment response in hepatocellular carcinoma.docx
Published 2025“…Prognostic models were developed and optimized via 10 machine learning algorithms with 10-fold cross-validation. …”