Presentation 1_Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence.pptx by Juan Chen (61123)

“…However, the evidence and regulatory mechanisms underlying decreased BDNF levels in CKD remain inconclusive.</p>Methods<p>This study systematically evaluated circulating BDNF alterations in CKD patients through a meta-analysis of clinical studies involving 1,549 participants, complemented by experimental validation in unilateral ureteral obstruction (UUO) mice and single-cell transcriptomic database analysis to investigate tissue-specific BDNF protein expression and regulatory patterns.…”

Data Sheet 1_Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence.docx by Juan Chen (61123)

“…However, the evidence and regulatory mechanisms underlying decreased BDNF levels in CKD remain inconclusive.</p>Methods<p>This study systematically evaluated circulating BDNF alterations in CKD patients through a meta-analysis of clinical studies involving 1,549 participants, complemented by experimental validation in unilateral ureteral obstruction (UUO) mice and single-cell transcriptomic database analysis to investigate tissue-specific BDNF protein expression and regulatory patterns.…”

Brain regions with significantly decreased activations for the Raven task are shown in blue. by Morteza Fattahi (15892028)

Claudin V is decreased following infection with Mtb. by Amanda S. Latham (12093638)

“…Exposure to Mtb H37Rv and HN878 decreased claudin V expression compared to uninfected controls in the frontal cortex (E), cerebral nuclei (J), brain stem (O), thalamus (T), and hippocampus (Y). …”

SBP3 KD decreases cytoadhesion of iRBCs to bovine brain endothelial cells (BBECs). by Atefeh Fathi (7370876)

Prenatal alcohol exposure (PAE) decreases brain and body weights at E14 and P0. by Danielle Sambo (6077924)

Voxel-based whole-hemisphere analysis shows regional and dose-dependent decrease of microglia. by Francesca Catto (21253435)

Selection frequencies plotted in decreasing order. by Hannah P. Rowe (7830599)

Variants in the three-way intersections of credible sets predicetd to alter chromatin accessibility in brain cell types. by Daniela Fusco (10027975)

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Voxel-based whole-brain analysis shows regional and dose-dependent effects of netoglitazone in decreasing plaque count. by Francesca Catto (21253435)

Forest plot showing the ratio of odds of hypothyroidism (=event) among pediatric brain cancer patients treated with either PT or XRT. by Renáta Kiss-Miki (20760127)

Subjects: “…without significantly decreasing…”

Forest plot showing the mean difference of global IQ level among pediatric brain cancer patients treated with either PT or XRT. by Renáta Kiss-Miki (20760127)

Subjects: “…without significantly decreasing…”

Forest plot showing the odds of 5-year overall-survival rate among children with brain tumors treated with either PT or XRT. by Renáta Kiss-Miki (20760127)

Subjects: “…without significantly decreasing…”

Voxel-based whole-brain analysis shows regional and dose-dependent effects of netoglitazone in decreasing plaque mean size. by Francesca Catto (21253435)

Genes associated by SMR to both BMI and at least one sMRI trait. by Daniela Fusco (10027975)

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Genetic correlations between sMRI traits and BMI. by Daniela Fusco (10027975)

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SMR reveals common molecular patterns. by Daniela Fusco (10027975)

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Network of colocalized causal variants. by Daniela Fusco (10027975)

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Epigenetic fine mapping and motif analysis for the TUFM locus. by Daniela Fusco (10027975)

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Credible sets and evidence of colocalization. by Daniela Fusco (10027975)

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