Glutamine Deprivation Induces Abortive S-Phase Rescued by Deoxyribonucleotides in <em>K-Ras</em> Transformed Fibroblasts by Daniela Gaglio (268212)

“…</p><h3>Methodology and Principal Findings</h3><p>Here, by using nutritional perturbations and molecular physiology, we show that reduction or complete depletion of glutamine availability in <em>K-ras</em> transformed fibroblasts causes a strong decrease of proliferation ability and a slower re-entry of synchronized cells into the cell cycle. …”

Histological assessment. by Guillaume Perrod (2548396)

“…<p>HES labelled esophagus slides centered on stricture area, obtained after digitalization and read using NDP.view software (magnification x0.25 and x0.32). In control group (A), there was an intense development of fibrosis (delimited by dotted line), with a systematical large destruction of the muscularis mucosae, an invasion of the inner muscularis layer and a high re-epithelialization defect. …”

Data_Sheet_1_In-Hospital Mortality of Sepsis Differs Depending on the Origin of Infection: An Investigation of Predisposing Factors.PDF by Mark Pieroni (12539632)

“…Clinical experience supports the concept that prognosis, treatment, severity, and time course of sepsis vary depending on the source of infection. We analyzed a large publicly available database to test this hypothesis. …”

Data_Sheet_1_New model of superior semicircular canal dehiscence with reversible diagnostic findings characteristic of patients with the disorder.pdf by P. Ashley Wackym (8123117)

“…There are two essential objective diagnostic characteristics needed to validate a model of SSCD: the creation of a pseudoconductive hearing loss and cVEMP increased amplitude and decreased threshold.…”

The total number of tumor cells during tumorigenesis. by Shingo Iwami (266092)

“…The total number of tumor cells decreases once the number of tumor variant types, , exceeds a threshold (for and ) and eventually suffers an error catastrophe as soon as the variant number exceeds (for ). …”

Comparative analysis of hemosorbents obtained at different modes by Assiya Nuraly (10472592)

“…<div><p>ABSTRACT When using hemosorbent laminar flow, a large active area of sorbents is used, the trauma of the blood corpuscles decreases dramatically, the ash content of the saline solution is absent. …”

Targeted silencing of GRP inhibited liver metastasis. by Pritha Paul (382332)

“…<p>(A) Large gross tumors were observed in the spleen and liver of mice injected with BE (2)-C/Tet/shCON and subjected to drinking water with doxycycline (2 mg/mL) and 3% sucrose [shCON (+DOX)] or injected with BE (2)-C/Tet/shGRP and subjected to drinking water with 3% sucrose alone [shGRP (-DOX)], whereas, a near complete inhibition of hepatic metastatic lesions was observed in mice subjected to drinking water with doxycycline (2 mg/mL) and 3% sucrose [shGRP (+DOX)]. …”

Homeostatic and circadian regulation of sleep-wake cycling. by Rupesh Kumar (144592)

“…During sleep, the homeostatic drive decreased, but the length of the sleep cycle was determined by intrinsic properties of POAH as is shown more clearly in the phase plane in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042059#pone-0042059-g003" target="_blank">Fig. 3</a>. …”

Allocating Police Resources While Limiting Racial Inequality by Andrew P. Wheeler (4529650)

“…Using data on stops and crime in New York City, I show that police stops can be more equitably distributed according to race, but there are fundamental trade-offs. One cannot gain a racial distribution of stops proportionately equal to the residential population without large decreases in the efficiency of targeting high crime areas. …”

The effects of distributed delay on transcriptional signaling. by Krešimir Josić (155006)

“…<p>(A) For the simplified symmetric distribution where the delay takes values and with equal probability, the mean signaling time decreases with increasing variability in delay time, Eq. (8). …”

Romanian subsidized start-ups by Bogdan-Nicolae Glavan (22682750)

“…<p dir="ltr">In 2015 the Romanian government began to subsidize the creation of start-ups, following a general policy of the European Union. We evaluate the effects of the Romania Start-up Program, which offered subsidies for hundreds of entrepreneurs in a large variety of economic sectors. …”

Network-level expression heterogeneity across tumor grades. by Chunjing Wang (469910)

“…<p><b>A)</b> Global trend of network regulation level decreases with increeasing grade. …”

Hydraulic modelling of instabilities on half-round circular weirs at three scales by Hubert Chanson (6563975)

“…Recent experimental works reported a number of instabilities, nonlinearities and hysteresis at medium to large discharges. …”

Spatial attractor dynamics in the feedback models. by Trygve Solstad (573123)

“…The model was simulated with 1000 random LEC input patterns and no MEC input over a range of feedback strengths (<i>J</i>). The output showed significant spatial tuning for large <i>J</i>. …”

IBS percentage in different relationships of simulated families. by Hong Li (20183)

“…Siblings have much of the genome that is easily detectable as IBD2, which GRAB detects through a large number of windows with a very high P2 statistic. …”

Potassium flux at corneal wounds. by Ana Carolina Vieira (238675)

“…This initial high concentration decreased over 5–20 min after wounding, reaching a stable lower value. …”

Correlation between discriminant axis and distance to chromatin marks on K562 cells. by Franck Picard (7471)

“…Note that origins (detected on K562 cells) associated with chromatin marks correspond to distance 0 (strict overlap). Large distances therefore correspond to origins that are strictly not associated with a given mark. …”

Cost-utility analysis of de-escalating biological disease-modifying anti-rheumatic drugs in patients with rheumatoid arthritis by Benjamin Birkner (8212203)

“…</p><p>Conclusion</p><p>Our findings suggest that de-escalating bDMARDs in patients with RA may result in high cost savings but also a decrease in quality of life compared to standard care. …”

The Modular Nature of Dendritic Cell Responses to Commensal and Pathogenic Fungi by Lisa Rizzetto (148311)

“…Then a marked decrease in the receptor levels follows, suggesting that at this moment the DC commits to a specific fate. …”

HEK-DP clones demonstrate increased mitochondrial fission. by Stephanie S. Kim (7230935)

“…In addition, the number of branches, large networks, and overall networks are significantly decreased in A9 and A11 (f-h) (*- p<0.05; **** -p<0.0001).…”