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14581
Table_1_Exogenous Alpha-Synuclein Evoked Parkin Downregulation Promotes Mitochondrial Dysfunction in Neuronal Cells. Implications for Parkinson’s Disease Pathology.DOCX
Published 2021“…While parkin plays an important role in mitochondrial biogenesis and turnover, including mitochondrial fission/fusion as well as mitophagy, the involvement of parkin deregulation in α-Syn-induced mitochondrial damage is largely unknown. In the present study, we demonstrated that treatment with exogenous α-Syn triggers mitochondrial dysfunction, reflected by the depolarization of the mitochondrial membrane, elevated synthesis of the mitochondrial superoxide anion, and a decrease in cellular ATP level. …”
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14582
Greater volumes are required to reduce muscle performance in well-trained individuals
Published 2018“…<div><p>Abstract A specific drop jumps (DJs) protocol (using 100 jumps) has been largely used to induce muscle damage. …”
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14583
Mixed Ligand Copper(II) Complexes of <i>N</i>,<i>N</i>-Bis(benzimidazol-2-ylmethyl)amine (BBA) with Diimine Co-Ligands: Efficient Chemical Nuclease and Protease Activities and Cyto...
Published 2012“…Interestingly, the 5,6-dmp complex <b>3</b> is selective in exhibiting a positive induced CD band (ICD) upon binding to DNA suggesting that it induces a B to A conformational change. …”
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14584
Mixed Ligand Copper(II) Complexes of <i>N</i>,<i>N</i>-Bis(benzimidazol-2-ylmethyl)amine (BBA) with Diimine Co-Ligands: Efficient Chemical Nuclease and Protease Activities and Cyto...
Published 2012“…Interestingly, the 5,6-dmp complex <b>3</b> is selective in exhibiting a positive induced CD band (ICD) upon binding to DNA suggesting that it induces a B to A conformational change. …”
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14585
Accuracy of consumer-level and research-grade activity trackers in ambulatory settings in older adults
Published 2019“…Waist-worn devices showed a more uniform performance. However, unstructured activities (e.g. dusting, playing cards), and using a walking aid represent a challenge for all wrist-worn trackers as evidenced by large MAPE (> 57.66% for dusting, > 67.32% when using a walking aid). …”
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14586
Comparison of Three Targeted Enrichment Strategies on the SOLiD Sequencing Platform
Published 2011“…<div><p>Despite the ever-increasing throughput and steadily decreasing cost of next generation sequencing (NGS), whole genome sequencing of humans is still not a viable option for the majority of genetics laboratories. …”
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14587
Table_1_Is air pollution detrimental to regional innovation? An empirical heterogeneity test based on Chinese cities.DOCX
Published 2022“…Air pollution has significant funds crowding-out effect and human capital loss effect, thereby decreasing the regional innovation level, which means innovation funds and researchers play a conductive role between air pollution and regional innovation. …”
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14588
Cortical bone in NF1 tibial dysplasia is characterized by heterogeneous mineralization, diminished collagen thickness and increased micro-porosity.
Published 2014“…However, in the NF1 bone sample HU values were in proximity of large vessels decreased (ROI2). The analyzed bone sample was obtained pre-fracture from an individual affected by NF1 with tibial bowing. …”
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14589
Diversity and Distribution Patterns of Cetaceans in the Subtropical Southwestern Atlantic Outer Continental Shelf and Slope
Published 2016“…As expected, densities of both small and large migratory whales were higher during spring, over the continental slope, in the southeast area. …”
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14590
Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV
Published 2016“…Our findings suggest that large numbers of patients—between 40 and 150—will be necessary to reliably estimate the reservoir-reducing potential of a new therapy and to compare this across interventions. …”
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14591
Hysteresis relation between cognitive performance and arousal.
Published 2010“…A sequence of phase portraits that corresponds to decreasing stressor (arousal) intensity is shown on the left panel. …”
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14592
On-Demand Indexing for Referential Compression of DNA Sequences
Published 2015“…<div><p>The decreasing costs of genome sequencing is creating a demand for scalable storage and processing tools and techniques to deal with the large amounts of generated data. …”
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14593
Effect of IL-6 deficiency on MCD diet-induced steatohepatitis.
Published 2013“…In IL-6<sup>−/−</sup> mice, steatosis was similarly present, but the number of inflammatory cells was decreased. The number of animals per group was 12 and 11 for WT mice, and 10 and 10 for IL-6<sup>−/−</sup>mice fed a normal or MCD diet, respectively. * p<0.05, *** p<0.001.…”
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14594
Graft of embryonic chick pancreas under SCID mouse kidney capsule.
Published 2013“…Morphometry analyses of erythrocytes staining (G), nestin immunohistochemistry (H) and mouse VEGFR2 <i>in situ</i> hybridization (I) showed a decreased number of endothelial cells (J, K and L). …”
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14595
Suppl. Fig. 5
Published 2020“…Microbial communities at genus level were significantly separated in the dendrogram by SIMPROF with 50% similarity between the small and large intestine sections<a>, and with 70% similarity between CON and HFF-fed pigs in cecum and colon </a><b>(B)</b>.…”
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14596
Status distributions in the extended model.
Published 2019“…Plots (b) and (d) show the distributions on a logarithmic scale, in order to allow for inspection of the large-<i>S</i> tail. …”
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14597
Persistence as Sustainability? Exploring Urban Longevity in Southwest Asia and Egypt - Dataset
Published 2025“…<p>The concept of settlement persistence, the duration of occupation of a settlement, has gained traction in archaeology as a way of articulating analyses of past societies in relation to sustainability science. …”
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14598
Table_1_Genetic Diversity of the Symbiotic Fungus Epichloë festucae in Naturally Occurring Host Grass Populations.XLSX
Published 2021“…We suggest that the postglacial distribution history of the host grass, prevailing reproduction strategies of E. festucae, and local selection pressures likely explain a large part of the genetic variation observed in fungal populations among geographic regions. …”
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14599
Table_1_Effect of Abdominal Circumference on the Irradiated Bowel Volume in Pelvic Radiotherapy for Rectal Cancer Patients: Implications for the Radiotherapy-Related Intestinal Tox...
Published 2022“…Compared with adjuvant radiotherapy, in neoadjuvant radiotherapy, the mean difference of irradiated bowel volume between patients with medium-large AC and those with small AC was larger.</p>Conclusion<p>AC is an independent factor influencing the irradiated bowel volume and has a strong negative linear correlation with it. …”
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14600
Image_1_Microvascular Dysfunction in Skeletal Muscle Precedes Myocardial Vascular Changes in Diabetic Cardiomyopathy: Sex-Dependent Differences.TIFF
Published 2022“…</p>Conclusion<p>Exercise intolerance manifesting early in the progression of diabetic cardiomyopathy can be attributed to decreased perfusion to the leg skeletal muscle due to perivascular smooth muscle thickening around small arterioles in females and large arterioles in males. …”