<b><i>PNLIPRP1</i></b><b> hypermethylation in exocrine pancreas links type 2 diabetes and cholesterol</b><b> metabolism</b> by Lucas Maurin (19346158)

“…Epigenome-wide association study (EWAS) for T2D identified a hypermethylation in an enhancer of the Pancreatic-Lipase-Related-Protein 1 (<i>PNLIPRP1</i>) gene, associated with decreased <i>PNLIPRP1</i> expression. …”

Datasheet1_Short-term exposure to ultrafine and fine particulate matter with multipollutant modelling on heart rate variability among seniors and children from the CorPuScula (coro... by Pascale Haddad (678636)

“…Results were largely unchanged for multipollutant modelling, however we found a more pronounced increase in SDNN and LF/HF (UFP lag 12 and 24 h) after adjusting for NO₂.…”

Datasheet1_Short-term exposure to ultrafine and fine particulate matter with multipollutant modelling on heart rate variability among seniors and children from the CorPuScula (coro... by Pascale Haddad (678636)

“…Results were largely unchanged for multipollutant modelling, however we found a more pronounced increase in SDNN and LF/HF (UFP lag 12 and 24 h) after adjusting for NO₂.…”

DataSheet_1_Obesity and diet independently affect maternal immunity, maternal gut microbiota and pregnancy outcome in mice.docx by Lieske Wekema (13231266)

“…Introduction<p>Maternal obesity poses risks for both mother and offspring during pregnancy, with underlying mechanisms remaining largely unexplored. Obesity is associated with microbial gut dysbiosis and low-grade inflammation, and also the diet has a major impact on these parameters. …”

DataSheet_1_Altered Serum Amino Acid and Acylcarnitine Profiles in Hyperinsulinemic Hypoglycemia and Ketotic Hypoglycemia.docx by Zhen-Ran Xu (9472850)

“…Background<p>In addition to inborn metabolic disorders, altered metabolic profiles were reported to be associated with the risk and prognosis of some non-metabolic diseases, while as a rare metabolic disease, the overall secondary metabolic spectrum in congenital hyperinsulinemic hypoglycemia (HH) is largely undetermined. …”

DataSheet_1_Impacts of coral bleaching on reef fish abundance, biomass and assemblage structure at remote Aldabra Atoll, Seychelles: insights from two survey methods.zip by Anna Koester (11805572)

“…In contrast, extended fish surveys in 2015 and 2020 showed a 55–60% reduction in overall abundance on shallow and deep reefs, and a 69% reduction in biomass on shallow reefs, with decreases in biomass occurring in all functional groups. …”

Effects of recombinant BDNF treatment on striatal atrophy in R6/2 mice. by Carmela Giampà (360711)

“…<p>Transmitted light microscope images showing representative Nissl-stained coronal sections of a wild-type mouse, a vehicle treated R6/2 mouse and a BDNF-treated R6/2 mouse, (A), left to right, respectively. …”

DataSheet_1_The gut microbiome in bullous pemphigoid: implications of the gut-skin axis for disease susceptibility.docx by Xiaolin Liu (403100)

“…Accumulating evidence points toward a link between the gut microbiota and skin diseases; however, the gut microbiota composition of BP patients remains largely underexplored, with only one pilot study to date, with a very limited sample size and no functional profiling of gut microbiota. …”

Data_Sheet_1_Effects of the COVID-19 pandemic on the physical activity and screen time habits of children aged 11–13 years in Sweden.DOCX by Sara Berggren (16802154)

“…We investigated PA and screen time in a cohort of Swedish children in both 2019 and 2021, before and during the pandemic.…”

DataSheet_2_The gut microbiome in bullous pemphigoid: implications of the gut-skin axis for disease susceptibility.xlsx by Xiaolin Liu (403100)

“…Accumulating evidence points toward a link between the gut microbiota and skin diseases; however, the gut microbiota composition of BP patients remains largely underexplored, with only one pilot study to date, with a very limited sample size and no functional profiling of gut microbiota. …”

Supplementary Material for: Hypothyroidism promotes microglia M1 polarization by inhibiting BDNF-promoted PI3K-Akt signaling pathway by Zhan Y. (4157410)

“…Conclusions: Our study demonstrated a sound conclusion that hypothyroidism promotes microglia M1 polarization by inhibiting BDNF-activated PI3K-Akt signaling pathway in brain, which could serve as a promising therapeutic target for microglia-induced neurodegenerative or emotional disorders in future.…”

Table_1_Comparative Genomic Analysis of Citrobacter and Key Genes Essential for the Pathogenicity of Citrobacter koseri.xlsx by Chao Yuan (408257)

“…Here, we determined an improved, detailed, and more accurate phylogeny of the genus Citrobacter based on whole genome sequence (WGS) data from 129 Citrobacter genomes, 31 of which were sequenced in this study. A maximum likelihood (ML) phylogeny constructed with core genome single-nucleotide polymorphisms (SNPs) classified all Citrobacter isolates into 11 distinct groups, with all C. koseri strains clustering into a single group. …”

Image_1_Localization, Gene Expression, and Functions of Glutamine Synthetase Isozymes in Wheat Grain (Triticum aestivum L.).PDF by Yihao Wei (10116574)

“…GS exhibited maximum activity and expression at 8 days after flowering (DAF) with peak glutamine content in grains; from then, NH4+ increased largely from NO3- reduction, glutamate dehydrogenase (GDH) aminating activity increased continuously, and the activities of GS and glutamate synthase (GOGAT) decreased, while only TaGS1;3 kept a stable expression in different TaGS isozymes. …”

Widespread chytrid infection across frogs in the Peruvian Amazon suggests critical role for low elevation in pathogen spread and persistence by Imani D. Russell (7507127)

“…Our results showing high and widespread prevalence across a lowland tropical ecosystem contradict the expectations based on the global pattern of pathogenicity of Bd that is largely restricted to higher elevations and colder temperatures. …”

Data_Sheet_2_Endoglin and squamous cell carcinomas.DOCX by Sarah K. Hakuno (16381851)

“…Interestingly, we observed that endoglin overexpression leads to strongly increased soluble endoglin levels, which in turn decreases BMP-9 signaling. On the functional level, endoglin, both in a ligand dependent and independent manner, did not influence proliferation or migration of the SCC cells. …”

Image_3_Sex linked behavioral and hippocampal transcriptomic changes in mice with cell-type specific Egr1 loss.tif by Cody Swilley (17203321)

“…Egr1 complete knockout mice demonstrate decreased depressive or anxiety-like behavior and impaired performance in spatial learning and memory. …”

The Trade-Off between Spatial and Temporal Variabilities in Reciprocal Upper-Limb Aiming Movements of Different Durations by Frederic Danion (482841)

“…<div><p>The spatial and temporal aspects of movement variability have typically been studied separately. As a result the relationship between spatial and temporal variabilities remains largely unknown. …”

Image_3_Modulation of Brain Activity by Selective Attention to Audiovisual Dialogues.TIFF by Alina Leminen (8825654)

“…Finally, attention to the dialogues, in relation to a control task where a fixation cross was attended and the dialogue ignored, yielded enhanced activity in the left planum polare, angular gyrus, the right temporal pole, as well as in the orbitofrontal/ventromedial prefrontal cortex and posterior cingulate gyrus. …”

Data_Sheet_1_Endoglin and squamous cell carcinomas.DOCX by Sarah K. Hakuno (16381851)

“…Interestingly, we observed that endoglin overexpression leads to strongly increased soluble endoglin levels, which in turn decreases BMP-9 signaling. On the functional level, endoglin, both in a ligand dependent and independent manner, did not influence proliferation or migration of the SCC cells. …”

Table_1_Localization, Gene Expression, and Functions of Glutamine Synthetase Isozymes in Wheat Grain (Triticum aestivum L.).DOCX by Yihao Wei (10116574)

“…GS exhibited maximum activity and expression at 8 days after flowering (DAF) with peak glutamine content in grains; from then, NH4+ increased largely from NO3- reduction, glutamate dehydrogenase (GDH) aminating activity increased continuously, and the activities of GS and glutamate synthase (GOGAT) decreased, while only TaGS1;3 kept a stable expression in different TaGS isozymes. …”