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19841
Table6_Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice.xlsx
Published 2022“…In addition, Tcf7l2 CKO mice with the olanzapine group showed significantly decreased expressions of GLP-1R protein and a trend of reduced pancreatic β-cell mass. …”
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19842
Factors associated with diversity, quantity and zoonotic potential of ectoparasites on urban mice and voles
Published 2018“…In addition, abundance of parasites with low host-specificity (ticks, fleas and chiggers) apparently decreased with increasing landscape fragmentation associated with a gradient of urbanisation. …”
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19843
Table_1_Cis- and Trans-Acting Expression Quantitative Trait Loci of Long Non-Coding RNA in 2,549 Cancers With Potential Clinical and Therapeutic Implications.docx
Published 2020“…In ovarian cancer, the “rs34631313-AC092580.4” pair was associated with increased fraction of CD8+ T cells and M1 Macrophage; whereas in KIRC, the “rs9546285-LINC00426” pair was associated with increased fraction of CD8+ T cells and a decreased fraction of M2 macrophages. Our findings provide a systematic view of the transcriptomic impacts of the eQTL landscape of lncRNA in human cancers and suggest its strong potential relevance to cancer immunity and treatment.…”
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19844
DataSheet1_Reduced B cell frequencies in cord blood of HIV-exposed uninfected infants: an immunological and transcriptomic analysis.pdf
Published 2024“…Additionally, we establish a 4-gene-based classifier that holds potential for predict immunological abnormalities in HEU infants.…”
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19845
Table_4_Early Chronic Memantine Treatment-Induced Transcriptomic Changes in Wild-Type and Shank2-Mutant Mice.XLSX
Published 2021“…Shank2-mutant mice with a homozygous deletion of exons 6 and 7 (Shank2-KO mice) show decreased NMDA receptor (NMDAR) function and autistic-like behaviors at juvenile [∼postnatal day (P21)] and adult (>P56) stages that are rescued by NMDAR activation. …”
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19846
Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2,3,7,8-Tetrachlorodibenzo‑<i>p</i>‑dioxin
Published 2017“…Both male and female samples exhibited similar qualitative changes (lipid species) but differed in quantitative changes. A shift to higher mass lipid species was observed, indicative of increased free fatty acid (FFA) packaging. …”
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19847
Data_Sheet_1_Preparation of Antimicrobial Hyaluronic Acid/Quaternized Chitosan Hydrogels for the Promotion of Seawater-Immersion Wound Healing.docx
Published 2019“…The results of in vitro and in vivo studies revealed that the prepared antibacterial hydrogels could largely inhibit bacterial growth. The in vivo study further demonstrated that the antibacterial hydrogels exhibited high repair efficiencies in a seawater-immersed wound defect model. …”
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19848
DataSheet1_Specific prostaglandins are produced in the migratory cells and the surrounding substrate to promote Drosophila border cell migration.pdf
Published 2024“…<p>Introduction: A key regulator of collective cell migration is prostaglandin (PG) signaling. …”
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19849
Image_4_Climatic and Resource Determinants of Forest Elephant Movements.pdf
Published 2020“…At the follow-level (2–4 day intervals), relative support for both rainfall and fruit availability decreased markedly, suggesting that at finer spatial scales forest elephants make foraging decisions largely based on other factors not directly assessed here. …”
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19850
Table_1_Initial Investment in Diversity Is the Efficient Thing to Do for Resilient Forest Landscape Restoration.DOCX
Published 2021“…This paper explores in detail the economic cost of improved integration of genetic diversity into restoration projects and tests the assumption that the benefits accruing from better integration of diversity exceed the costs. Using a bottom-up cost model, based on peer reviewed scientific literature, we analyse different FLR cost drivers, integrating genetic quality, in relation to the total costs of a range of tree-based restoration interventions, with a focus on seed sourcing, and tree species selection. …”
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19851
DataSheet1_Curcumin enhances the anti-cancer efficacy of paclitaxel in ovarian cancer by regulating the miR-9-5p/BRCA1 axis.pdf
Published 2023“…<p>Background: Patients with late-stage ovarian cancer still have a very poor prognosis due to chemotherapy resistance. …”
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19852
Table4_Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice.xlsx
Published 2022“…In addition, Tcf7l2 CKO mice with the olanzapine group showed significantly decreased expressions of GLP-1R protein and a trend of reduced pancreatic β-cell mass. …”
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19853
Table_2_Early Chronic Memantine Treatment-Induced Transcriptomic Changes in Wild-Type and Shank2-Mutant Mice.XLSX
Published 2021“…Shank2-mutant mice with a homozygous deletion of exons 6 and 7 (Shank2-KO mice) show decreased NMDA receptor (NMDAR) function and autistic-like behaviors at juvenile [∼postnatal day (P21)] and adult (>P56) stages that are rescued by NMDAR activation. …”
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19854
Table8_Olanzapine Promotes the Occurrence of Metabolic Disorders in Conditional TCF7L2-Knockout Mice.xlsx
Published 2022“…In addition, Tcf7l2 CKO mice with the olanzapine group showed significantly decreased expressions of GLP-1R protein and a trend of reduced pancreatic β-cell mass. …”
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19855
Table_1_Fibronectin leucine-rich transmembrane protein 2 drives monocyte differentiation into macrophages via the UNC5B-Akt/mTOR axis.xlsx
Published 2023“…However, the regulatory mechanisms underlying monocyte-to-macrophage differentiation remain largely unexplored. Here we divulge a previously uncharacterized but essential role for an axon guidance molecule, fibronectin leucine-rich transmembrane protein 2 (FLRT2), in monocyte-to-macrophage maturation. …”
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19856
Image 1_Analgesic effect of Dahuang Fuzi Decoction in neuropathic pain through inhibiting TNF-α and PI3K-AKT signaling.jpeg
Published 2024“…A chronic sciatic nerve compression injury (CCI) rat mode was used to assess the analgesic efficacy of DF for NeP. …”
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19857
Table_8_Cis- and Trans-Acting Expression Quantitative Trait Loci of Long Non-Coding RNA in 2,549 Cancers With Potential Clinical and Therapeutic Implications.docx
Published 2020“…In ovarian cancer, the “rs34631313-AC092580.4” pair was associated with increased fraction of CD8+ T cells and M1 Macrophage; whereas in KIRC, the “rs9546285-LINC00426” pair was associated with increased fraction of CD8+ T cells and a decreased fraction of M2 macrophages. Our findings provide a systematic view of the transcriptomic impacts of the eQTL landscape of lncRNA in human cancers and suggest its strong potential relevance to cancer immunity and treatment.…”
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19858
Data_Sheet_1_Inflammation-activated C/EBPβ mediates high-fat diet-induced depression-like behaviors in mice.PDF
Published 2022“…Besides, the loss of C/EBPβ expression in C/EBPβ heterozygous knockout male mice attenuated HFD-induced depression-like behaviors, whereas Thy1-C/EBPβ transgenic male mice (overexpressing C/EBPβ) showed depressive behaviors after a short-term HFD. Furthermore, HFD impaired synaptic plasticity and decreased surface expression of glutamate receptors in the hippocampus of wild-type (WT) mice, but not in C/EBPβ heterozygous knockout mice. …”
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19859
Tropical fishes can benefit more from novel than familiar species interactions at their cold-range edges
Published 2025“…Whether such novel species interactions facilitate or inhibit range extensions remains largely unknown.</p><p dir="ltr">2. We evaluated how range-extending tropical and co-shoaling temperate fishes modify their behaviours (aggression, foraging, and anti-predator) along a 2,000-km latitudinal gradient encapsulating tropical, subtropical and temperate reefs in a global ocean warming hotspot.…”
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19860
DataSheet_1_Fibronectin leucine-rich transmembrane protein 2 drives monocyte differentiation into macrophages via the UNC5B-Akt/mTOR axis.pdf
Published 2023“…However, the regulatory mechanisms underlying monocyte-to-macrophage differentiation remain largely unexplored. Here we divulge a previously uncharacterized but essential role for an axon guidance molecule, fibronectin leucine-rich transmembrane protein 2 (FLRT2), in monocyte-to-macrophage maturation. …”