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19941
Data_Sheet_1_Influence of perinatal and childhood exposure to tobacco and mercury in children’s gut microbiota.pdf
Published 2024“…Background<p>Early life determinants of the development of gut microbiome composition in infants have been widely investigated; however, if early life pollutant exposures, such as tobacco or mercury, have a persistent influence on the gut microbial community, its stabilization at later childhood remains largely unknown.…”
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19942
Maternal and Paternal Genomes Differentially Affect Myofibre Characteristics and Muscle Weights of Bovine Fetuses at Midgestation
Published 2013“…<div><p>Postnatal myofibre characteristics and muscle mass are largely determined during fetal development and may be significantly affected by epigenetic parent-of-origin effects. …”
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19943
PKC activation accelerates the removal of receptors from synaptic sites <i>in</i><i>vivo</i>.
Published 2013“…<p><i>A</i>, Labeling protocol for assessing the removal of preexisting AChRs from the postsynaptic membrane. …”
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19944
Image_3_GPR15 in colon cancer development and anti-tumor immune responses.jpeg
Published 2023“…GPR15 function in colon cancer is largely unexplored, motivating our current studies.…”
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19945
Filamentous calcareous alga provides substrate for coral-competitive macroalgae in the degraded lagoon of Dongsha Atoll, Taiwan
Published 2019“…By providing habitat for other harmful macroalgae, a prolonged <i>Galaxaura</i> overgrowth could further enhance the spread of macroalgae, and strengthen negative feedback loops, decreasing the recovery potential of degraded reefs.…”
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19946
Supplementary file 1_Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stroma...
Published 2025“…Ethnopharmacological relevance<p>Shaoyao Gancao Decoction (SGD) is a renowned traditional Chinese medicinal formulation widely utilized in Asia. …”
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19947
Supplementary file 2_Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stroma...
Published 2025“…Ethnopharmacological relevance<p>Shaoyao Gancao Decoction (SGD) is a renowned traditional Chinese medicinal formulation widely utilized in Asia. …”
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19948
Image3_The Lipid-Binding Defective Dynamin 2 Mutant in Charcot-Marie-Tooth Disease Impairs Proper Actin Bundling and Actin Organization in Glomerular Podocytes.tif
Published 2022“…Reformation of stress fibers after cytochalasin D-induced actin depolymerization and washout was less effective in dynamin 2-K562E-expressing cells than that in dynamin 2-WT. Bis-T-23, a dynamin self-assembly enhancer, was unable to rescue the decreased focal adhesion numbers and reduced stress fiber density induced by dynamin 2-K562E expression. …”
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19949
Image2_The Lipid-Binding Defective Dynamin 2 Mutant in Charcot-Marie-Tooth Disease Impairs Proper Actin Bundling and Actin Organization in Glomerular Podocytes.tif
Published 2022“…Reformation of stress fibers after cytochalasin D-induced actin depolymerization and washout was less effective in dynamin 2-K562E-expressing cells than that in dynamin 2-WT. Bis-T-23, a dynamin self-assembly enhancer, was unable to rescue the decreased focal adhesion numbers and reduced stress fiber density induced by dynamin 2-K562E expression. …”
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19950
Image1_The Lipid-Binding Defective Dynamin 2 Mutant in Charcot-Marie-Tooth Disease Impairs Proper Actin Bundling and Actin Organization in Glomerular Podocytes.tif
Published 2022“…Reformation of stress fibers after cytochalasin D-induced actin depolymerization and washout was less effective in dynamin 2-K562E-expressing cells than that in dynamin 2-WT. Bis-T-23, a dynamin self-assembly enhancer, was unable to rescue the decreased focal adhesion numbers and reduced stress fiber density induced by dynamin 2-K562E expression. …”
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19951
TopBP1 governs HSPCs survival during pool expansion in CHT.
Published 2015“…After the loading of replication protein A (RPA), ATR/ATRIP, and 9-1-1 complex, sequential participation of TopBP1 can largely activate ATR kinase activity, and the latter phosphorylate downstream targets such as Chk1. …”
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19952
Image_1_Role of Phosphatidylinositol 3-Kinase (PI3K), Mitogen-Activated Protein Kinase (MAPK), and Protein Kinase C (PKC) in Calcium Signaling Pathways Linked to the α1-Adrenocepto...
Published 2019“…The PI3K blocker LY-294002 moderately reduced intracellular Ca<sup>2+</sup> release, Ca<sup>2+</sup> entry and contraction induced by the α<sub>1</sub>-adrenoceptor agonist, while PKC inhibition decreased PE-elicited Ca<sup>2+</sup> entry and to a lesser extent contraction without affecting intracellular Ca<sup>2+</sup> mobilization. …”
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19953
Image_2_Role of Phosphatidylinositol 3-Kinase (PI3K), Mitogen-Activated Protein Kinase (MAPK), and Protein Kinase C (PKC) in Calcium Signaling Pathways Linked to the α1-Adrenocepto...
Published 2019“…The PI3K blocker LY-294002 moderately reduced intracellular Ca<sup>2+</sup> release, Ca<sup>2+</sup> entry and contraction induced by the α<sub>1</sub>-adrenoceptor agonist, while PKC inhibition decreased PE-elicited Ca<sup>2+</sup> entry and to a lesser extent contraction without affecting intracellular Ca<sup>2+</sup> mobilization. …”
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19954
Distribution of meprin α<sub>1</sub>, α<sub>2</sub> and β in zebrafish tissues.
Published 2010“…Evidently, the expression of meprin α<sub>2</sub> in the <i>lamina propria (LP)</i> of the intestine is largely decreased (G, H). Similar analyses of the meprin β morphant were not possible, due to the lethality within 24 hpf. …”
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19955
Glucose Amplifies Fatty Acid-Induced Endoplasmic Reticulum Stress in Pancreatic β-Cells <em>via</em> Activation of mTORC1
Published 2009“…<div><h3>Background</h3><p>Palmitate is a potent inducer of endoplasmic reticulum (ER) stress in β-cells. …”
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19956
New Steric Hindrance Approach Employing the Hybrid Ligand 2-Aminomethylpiperidine for Diminishing Dynamic Motion Problems of Platinum Anticancer Drug Adducts Containing Guanine Der...
Published 1999“…However, at pH 9.5, where the 5‘-GMP N1H was largely deprotonated, the NMR spectrum and the ∼280 nm CD peak both revealed that the ΛHT form had decreased. …”
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19957
Suppression of autophagy and HCK signaling promotes PTGS2<sup>high</sup> FCGR3<sup>−</sup> NK cell differentiation triggered by ectopic endometrial stromal cells
Published 2018“…The reason for the impaired cytotoxic activity of NK cells in an ectopic lesion microenvironment (ELM) is largely unknown. In this study, we show that the macroautophagy/autophagy level of endometrial stromal cells (ESCs) from EMS decreased under negative regulation of estrogen. …”
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19958
Informing Policy and Management in New Zealand Agricultural Regions Using Nitrogen and Oxygen Isotopes to Quantify Hot Spots and Hot Moments of Nitrate Loss. AGU Fall Meeting, San...
Published 2021“…Exploration of catchments with higher proportions of crop-based agricultural land use, as well as highly intensive grazing with a decreased reliance on pastoral cover, show migration to lower δ15N values with no change in δ18O. …”
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19959
Altered spatial distribution of EPDCs in <i>Wt1</i><sup>Cre</sup>; <i>Sox9</i><sup>fl/fl</sup>; <i>R26</i><sup>mG</sup> hearts.
Published 2025“…<b>(I)</b> Nearest-neighbor analysis reveals a decreased average distance between GFP+ object centroids and their nearest CD109 + neighbor in <i>Wt1</i><sup>Cre</sup>; <i>Sox9</i><sup>fl/fl</sup>; <i>R26</i><sup>mG</sup> specimens. …”
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19960
Data_Sheet_1_Genome Size Variation and Evolution Driven by Transposable Elements in the Genus Oryza.xlsx
Published 2022“…Our results showed that the species belonging to the same genome types had similar genome sizes, while genome sizes exhibited a gradually decreased trend during the evolutionary process in the clade with AA, BB, CC, and EE genome types. …”