Inotodiol decreases clone formation in HCC cells. حسب Yushuang Xing (20636685)

"…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …"

Inotodiol decreases clone formation in HCC cells. حسب Yushuang Xing (20636685)

IFN-γ and several PARP genes are upregulated in infected olfactory bulbs of JHMV infected mice. حسب Catherine M. Kerr (21492574)

PARP9 knockdown promotes apoptosis and DNA damage. حسب Yating Li (1819822)

"…(E) DNA damage in GC cells significantly increased post-PARP9 knockdown as determined by comet assay. (F) The anti-DNA damage capacity of GC cells decreased markedly following reduction of PARP9 expression. …"

Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf حسب Maria Delgado-Ortet (8840702)

"…In this work, we developed noninvasive imagingbased measurements of spatial and longitudinal heterogeneity in a retrospective analysis of a phase 2 non-randomized study of germline BRCA1/BRCA2 mutated (gBRCAm) ovarian cancer patients treated with combination of PARP inhibitors (PARPi) and immune checkpoint inhibitors (ICIs).…"

PARP cleavage analysis of sgCtrl and <i>IRF1</i> KO cells across conditions with and without vaccinia virus infection. حسب Tyron Chang (9922533)

Table 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.xlsx حسب Nevena Grdović (394542)

"…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …"

Data Sheet 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.pdf حسب Nevena Grdović (394542)

"…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …"

Figure 3 from Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation حسب Anna Rutkowska (19676837)

Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53 حسب Mete Keçeci (20479508)

"…Expressions of p53 and Poly [ADP-ribose] polymerase 1 (PARP-1) increased significantly in the MTX group compared to the other groups (<i>p</i> < 0,05).…"

ELISA and RT-qPCR evaluation of cytokines in the embryonic mouse brain. حسب Adrienne J. Bradley (20861948)

Over expression of SOX6 attenuates apoptosis and DNA damage in AGS cells. حسب Yating Li (1819822)

"…(B) At the protein level, it was confirmed that SOX6 levels decreased concomitantly with diminishing PARP9 expression. …"

Statins increased neuronal soma membrane complexity. حسب Shuk C. Tsoi (21192243)

Statins resulted in smaller neuronal soma size. حسب Shuk C. Tsoi (21192243)

Figure S1 from PARP Inhibition Induces Synthetic Lethality and Adaptive Immunity in LKB1-Mutant Lung Cancer حسب Li-Li Long (14963775)

Dehydrozingerone Improves Mood and Memory in Diabetic Mice via Modulating Core Neuroimmune Genes and Their Associated Proteins حسب Anuradha Kesharwani (21386000)

الموضوعات:

Aquaporin 4 Expression and Size Dependent Solute Movement in the Brain حسب Ethan Chang (20448602)

"…Compared to the AQP4 KO mice, wild type mice were visually observed to exhibit greater brain tissue/parenchymal tracer influx as opposed to the increased perivascular/pial tracer circulation in the AQP4 KO mice. …"

Analysis of DCX⁺ cells showing migratory morphology (cells with small, oval/fusiform cell soma – less than 9 µm – and an unbranched leading process) in the amygdala of a... حسب Marco Ghibaudi (16701750)

Occurrence of subcortical immature neurons (scINs) in the amygdala of mouse and primates: relationship with evolution of subnuclei scaling and cortical connectomics. حسب Marco Ghibaudi (16701750)

Neuropsychological Test Measures. حسب Michael R. Lawrence (21369854)

"…Serum levels of nerve growth factor (NGF), a biomarker of brain plasticity, were significantly lower in the long COVID group, which was significantly more likely than controls to have serum levels of inflammatory marker (interleukin (IL)-10) values greater than or equal to the median (p = 0.015). …"