Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

“…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …”

Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

Data Sheet 1_Aging of visual word perception is related to decreased segregation within and beyond the word network in the brain.docx by Licheng Xue (6683348)

“…Introduction<p>We investigated the neural correlates of cognitive decline in visual word perception from the perspective of intrinsic brain networks.…”

IFN-γ and several PARP genes are upregulated in infected olfactory bulbs of JHMV infected mice. by Catherine M. Kerr (21492574)

PARP9 knockdown promotes apoptosis and DNA damage. by Yating Li (1819822)

“…(E) DNA damage in GC cells significantly increased post-PARP9 knockdown as determined by comet assay. (F) The anti-DNA damage capacity of GC cells decreased markedly following reduction of PARP9 expression. …”

Table_2_Maternal oral probiotic use is associated with decreased breastmilk inflammatory markers, infant fecal microbiome variation, and altered recognition memory responses in inf... by Sara Gonia (14132166)

“…In this observational study, we explore if early life exposure to probiotics via the mother during pregnancy and lactation, is associated with decreased inflammation in breastmilk, maternal and infant microbiome variation, and altered infant neurodevelopmental features.…”

Table_1_Maternal oral probiotic use is associated with decreased breastmilk inflammatory markers, infant fecal microbiome variation, and altered recognition memory responses in inf... by Sara Gonia (14132166)

“…In this observational study, we explore if early life exposure to probiotics via the mother during pregnancy and lactation, is associated with decreased inflammation in breastmilk, maternal and infant microbiome variation, and altered infant neurodevelopmental features.…”

Reproducibility of response time and brain measures. by Jan Willem Koten (17743224)

Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf by Maria Delgado-Ortet (8840702)

“…In this work, we developed noninvasive imagingbased measurements of spatial and longitudinal heterogeneity in a retrospective analysis of a phase 2 non-randomized study of germline BRCA1/BRCA2 mutated (gBRCAm) ovarian cancer patients treated with combination of PARP inhibitors (PARPi) and immune checkpoint inhibitors (ICIs).…”

PARP cleavage analysis of sgCtrl and <i>IRF1</i> KO cells across conditions with and without vaccinia virus infection. by Tyron Chang (9922533)

Table 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.xlsx by Nevena Grdović (394542)

“…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …”

Data Sheet 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.pdf by Nevena Grdović (394542)

“…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …”

Figure 3 from Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation by Anna Rutkowska (19676837)

Summary of the framework for the computation of the brain transition cost from EEG data. by Giacomo Barzon (19832364)

Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53 by Mete Keçeci (20479508)

“…Expressions of p53 and Poly [ADP-ribose] polymerase 1 (PARP-1) increased significantly in the MTX group compared to the other groups (<i>p</i> < 0,05).…”

ELISA and RT-qPCR evaluation of cytokines in the embryonic mouse brain. by Adrienne J. Bradley (20861948)

Over expression of SOX6 attenuates apoptosis and DNA damage in AGS cells. by Yating Li (1819822)

“…(B) At the protein level, it was confirmed that SOX6 levels decreased concomitantly with diminishing PARP9 expression. …”

Statins increased neuronal soma membrane complexity. by Shuk C. Tsoi (21192243)

Statins resulted in smaller neuronal soma size. by Shuk C. Tsoi (21192243)

Calycosin Inhibit PANoptosis and Alleviate Brain Damage: A Bioinformatics and Experimental Verification Approach by Huiyan An (20959966)

“…Numerous studies have highlighted the significance of PANoptosis in brain ischemia–reperfusion (I/R) injury. Calycosin, a natural product with diverse biological activities, has demonstrated a significant reduction in neuronal death caused by ischemic brain injury by modulating multiple cell death pathways. …”