بدائل البحث:
parp decrease » a decrease (توسيع البحث), pa decreased (توسيع البحث), step decrease (توسيع البحث)
we decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
nn decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
parp decrease » a decrease (توسيع البحث), pa decreased (توسيع البحث), step decrease (توسيع البحث)
we decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
nn decrease » _ decrease (توسيع البحث), a decrease (توسيع البحث), mean decrease (توسيع البحث)
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Inotodiol decreases clone formation in HCC cells.
منشور في 2025"…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …"
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Data Sheet 1_Aging of visual word perception is related to decreased segregation within and beyond the word network in the brain.docx
منشور في 2024"…Introduction<p>We investigated the neural correlates of cognitive decline in visual word perception from the perspective of intrinsic brain networks.…"
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PARP9 knockdown promotes apoptosis and DNA damage.
منشور في 2024"…(E) DNA damage in GC cells significantly increased post-PARP9 knockdown as determined by comet assay. (F) The anti-DNA damage capacity of GC cells decreased markedly following reduction of PARP9 expression. …"
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Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf
منشور في 2025"…In this work, we developed noninvasive imagingbased measurements of spatial and longitudinal heterogeneity in a retrospective analysis of a phase 2 non-randomized study of germline BRCA1/BRCA2 mutated (gBRCAm) ovarian cancer patients treated with combination of PARP inhibitors (PARPi) and immune checkpoint inhibitors (ICIs).…"
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Table 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.xlsx
منشور في 2025"…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …"
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Data Sheet 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.pdf
منشور في 2025"…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …"
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Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53
منشور في 2024"…Expressions of p53 and Poly [ADP-ribose] polymerase 1 (PARP-1) increased significantly in the MTX group compared to the other groups (<i>p</i> < 0,05).…"
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14
Over expression of SOX6 attenuates apoptosis and DNA damage in AGS cells.
منشور في 2024"…(B) At the protein level, it was confirmed that SOX6 levels decreased concomitantly with diminishing PARP9 expression. …"
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15
Calycosin Inhibit PANoptosis and Alleviate Brain Damage: A Bioinformatics and Experimental Verification Approach
منشور في 2025"…Numerous studies have highlighted the significance of PANoptosis in brain ischemia–reperfusion (I/R) injury. Calycosin, a natural product with diverse biological activities, has demonstrated a significant reduction in neuronal death caused by ischemic brain injury by modulating multiple cell death pathways. …"
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16
Design and Synthesis of Novel PET Radiotracers for Imaging Sphingosine-1-Phosphate Receptor 5 (S1PR5) in the Brain
منشور في 2025"…Cuprizone-fed mice had reduced [<sup>18</sup>F]<b>7a</b> brain uptake, reflecting the loss of oligodendrocytes and decreased S1PR5 expression. …"
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17
Design and Synthesis of Novel PET Radiotracers for Imaging Sphingosine-1-Phosphate Receptor 5 (S1PR5) in the Brain
منشور في 2025"…Cuprizone-fed mice had reduced [<sup>18</sup>F]<b>7a</b> brain uptake, reflecting the loss of oligodendrocytes and decreased S1PR5 expression. …"
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Design and Synthesis of Novel PET Radiotracers for Imaging Sphingosine-1-Phosphate Receptor 5 (S1PR5) in the Brain
منشور في 2025"…Cuprizone-fed mice had reduced [<sup>18</sup>F]<b>7a</b> brain uptake, reflecting the loss of oligodendrocytes and decreased S1PR5 expression. …"
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