Comparison of WT and mutant SHC014-CoV S ectodomains. by Alexandra L. Tse (20235212)

“…A835D-containing variants exhibit a large decrease in protein expression relative to the WT and F294L SHC014-CoV spikes. …”

The Enzyme Effect: Broadening the Horizon of MS Optimization to Nontryptic Digestion in Proteomics by Kinga Nagy (603019)

“…We analyzed peptide scores for thousands of peptides and determined optimal collision energy (CE) values. Our results showed a linear <i>m</i>/<i>z</i> dependence for all enzymes, with Glu-C, Asp-N, and chymotrypsin requiring significantly lower energies than trypsin and Arg-C. …”

Plot of percent saccade error over time. by Lee Friedman (4062949)

“…Across the entire 100 sec of the task, median total fixation duration decreased. This decrease was approximated with a power law fit with <i>R</i>² = 0.94. …”

Plot of the median saccade error over time. by Lee Friedman (4062949)

“…Across the entire 100 sec of the task, median total fixation duration decreased. This decrease was approximated with a power law fit with <i>R</i>² = 0.94. …”

Long-term changes in the density and composition of profundal macrobenthos in Lake Biwa from 1966 to 2000 by Tetsuya Narita (19330967)

“…Notably, the increase in <i>T. tubifex</i> density roughly coincided with density decreases in the benthic gobid fish <i>Gymnogobius isaza</i> (from 567 t to undetectable) and the shrimp <i>Palaemon paucidens</i> (from 758 to 142 t). …”

Mitotic phenotypes caused by co-depletion of CAMSAP2 and HAUS6. by Naoko Nishizawa (20536299)

“…BubR1-negative spindles were exclusively chosen as metaphase ones to measure the metaphase spindle length based on α-tubulin signals. n = 55 cells (si control WT), 58 (si HAUS6 WT), 47 (si control CAMSAP2 KO) and 66 (si HAUS6 CAMSAP2 KO) from 3 independent experiments. …”

<b>Prescribing trends of anti-diabetes medications near end-of-life among adults with type 2 diabetes: a cohort study</b> by Alexander Kutz (3172095)

“…The most pronounced increase in use was observed for metformin (40.7% to 46.5%; SMD, -0.12), whereas the largest decrease was observed for sulfonylureas (37.0% to 31.8%; SMD, 0.11). …”

Update on trimethylamine N-oxide (TMAO) as a piezolyte and cryoprotectant: its role in a depth limit for marine fishes and loss from hadal fish during capture by Paul Yancey (14354982)

“…</p><p dir="ltr">•<i>TMAO down-regulation during retrieval</i>: a very different possibility for decreasing TMAO content during retrieval assumes that deep-sea fish actively regulate TMAO to match the pressure they are experiencing. …”

Grid division diagram. by Ming Zhang (9736)

“…Between the second and third sand-blocking fences, when the height of sand-blocking fence is 2.5m, the increase of wind speed is 13.87% lower than that of 2m height. The decrease is the largest, and sand particles are easy to deposit here in large quantities. …”

Model calculation diagram. by Ming Zhang (9736)

“…Between the second and third sand-blocking fences, when the height of sand-blocking fence is 2.5m, the increase of wind speed is 13.87% lower than that of 2m height. The decrease is the largest, and sand particles are easy to deposit here in large quantities. …”

Grid independence verification. by Ming Zhang (9736)

“…Between the second and third sand-blocking fences, when the height of sand-blocking fence is 2.5m, the increase of wind speed is 13.87% lower than that of 2m height. The decrease is the largest, and sand particles are easy to deposit here in large quantities. …”

Development of a machine learning method for predicting neutrophil-specific functional genes. by Guihua Wang (286390)

“…<p>(A) NeuRGI model training workflow involved: 1) extracting gene features from various databases. 2) using genes of neutrophil-related genes as positives and PU-learning as negatives. 3) balancing the training set with under-sampling and training the NeuRGI random forest model with 10-fold cross-validation, then employing a Gaussian Mixture Model (GMM) with NeuRGI scores to identify potential positives. 4) using OntoVAE for <i>in silico</i> knockout of GMM-classified genes to find key regulatory factors for guiding follow-up experiments. …”

Image3_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.jpeg by Elena Chiappini (304802)

“…</p>Methods<p>A cross-sectional anonymous survey was conducted among a large sample of primary care and hospital pediatricians. …”

Image2_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.jpeg by Elena Chiappini (304802)

“…</p>Methods<p>A cross-sectional anonymous survey was conducted among a large sample of primary care and hospital pediatricians. …”

Image1_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.jpeg by Elena Chiappini (304802)

“…</p>Methods<p>A cross-sectional anonymous survey was conducted among a large sample of primary care and hospital pediatricians. …”

Image4_Fever management in children and insights into fever of unknown origin: a survey among Italian pediatricians.jpeg by Elena Chiappini (304802)

“…</p>Methods<p>A cross-sectional anonymous survey was conducted among a large sample of primary care and hospital pediatricians. …”

Sensitivity of biomass and cumulative harvest to magnitude of climate impacts under alternative management strategies. by Jameal F. Samhouri (10136090)

“…All parameters except for the percent change in demographic parameters are at their default values; note that initial and final values of productivity and carrying capacity differ in the decreasing versus increasing scenarios (<a href="/article/info:doi/10.1371/journal.pclm.0000624#pclm.0000624.s002" target="_blank">S1</a>-<a href="/article/info:doi/10.1371/journal.pclm.0000624#pclm.0000624.s003" target="_blank">S2 Tables</a>).…”

Memory effect on effective memory lifetime. by Katherine Daftari (20910118)

“…<p>(A) The average mutual information as a function of delay time decreases as the value of <i>μ</i> increases and the self-avoidant memory response is suppressed. …”

Data Sheet 1_Effects of growth years on the quality of cultivated Bupleurum scorzonerifolium roots, with wild Bupleurum scorzonerifolium roots as a reference.docx by Changsheng Yuan (2369854)

“…The ratio of phloem width to xylem radius, along with the contents of total saponins and saikosaponins a, b2, c, and d, exhibited a trend of initial decrease, followed by an increase. …”

Data Sheet 1_Comparative efficacy and safety of antidiabetic agents for post-transplant diabetes mellitus: a network meta-analysis.docx by Shanbiao Hu (15063765)

“…DPP-4 inhibitors showed the most pronounced decrease in SBP (MD − 3.57 mmHg, 95% CI − 7.29 to 0.16). …”