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Targeting of lactate dehydrogenase C dysregulates the cell cycle and sensitizes breast cancer cells to DNA damage response targeted therapy
منشور في 2021"…<div><p>The cancer testis antigen (CTA) lactate dehydrogenase C (LDHC) is a promising anticancer target with tumor‐specific expression and immunogenicity. …"
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First-Principles Density Functional Theory Calculations of Bilayer Membranes Heterostructures of Ti<sub>3</sub>C<sub>2</sub>T<sub>2</sub> (MXene)/Graphene and AgNPs
منشور في 2021"…We also studied the structural properties of Ti<sub>3</sub>C<sub>2</sub>X<sub>2</sub> MXene (X = F, O and OH) decorated with silver nanoclusters Ag<sub>n</sub> (n ≤ 6). …"
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Prostaglandin E2 stimulates p53 transactivational activity through specific serine 15 phosphorylation in human synovial fibroblasts ROLE IN SUPPRESSION OF c/EBP/NF-κB-MEDIATED MEKK...
منشور في 2006"…MEKK1-induced MMP-1 promoter-driven luciferase activity was largely dependent on a c/EBPβ-NF-κB-like enhancer site at –2008 to –1972 bp, as judged by deletion and point mutation analyses. …"
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Controlling a traumatic injury
منشور في 2015"…</p><p>“Misdiagnosis can be reduced by raising awareness about the condition and increasing the use of imaging, especially CT scans,” says Mohammed.…"
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Gastroesophageal Cancer After Gastric Bypass Surgeries
منشور في 2022"…Data comparing the occurrence of gastroesophageal cancer after gastric bypass procedures are lacking and are only available in the form of case reports. We perform in this study a systematic review and a meta-analysis of all the reported cases of gastroesophageal cancer following Roux-en-Y gastric bypass (RYGB) and loop gastric bypass-one anastomosis gastric bypass/mini gastric bypass (LGB-OAGB/MGB). …"
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Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases
منشور في 2010"…For example, a few years ago an extrahepatic metastasis effectively eliminated surgical resection, but a combination of chemotherapeutic options and surgical techniques has expanded the indications for resection and increased the population of patients who may benefit.1,2 Neoadjuvant chemotherapy has increased the resectability rate by 11% to 37%.1 Unfortunately, greater than 80% of patients undergoing hepatic resection will have recurrences, mostly within the first 2 years.2 Nonetheless, the only hope for cure is resection, and prior surgical dogma based on the number of lesions, size of the tumor-free resection margin, and presence of resectable extrahepatic disease must be questioned.3- 5 The current standard approach to surgical planning is contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) for specific tumor characteristics or contraindications to CT.6 Several series showed that focal extrahepatic disease, an isolated pulmonary lesion, can be safely resected, with 5-year survival rates of 29% to 58%.7,8 In 1 series,7 17 of 30 patients required 3 or more resections. …"
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Platelet Protein-Related Abnormalities in Response to Acute Hypoglycemia in Type 2 Diabetes
منشور في 2021"…When infected with COVID-19, this risk may be compounded, and their propensity for a more severe COVID-19 disease course increased.</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Endocrinology<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fendo.2021.651009" target="_blank">https://dx.doi.org/10.3389/fendo.2021.651009</a></p><p dir="ltr">Clinical Trial Registration: <a href="https://clinicaltrials.gov/ct2/show/NCT03102801" target="_blank">https://clinicaltrials.gov/ct2/show/NCT03102801</a>, identifier NCT03102801</p>…"
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An unusual etiology of bilateral pulmonary nodules: Another challenge of hide and seek
منشور في 2021"…As the patient was asymptomatic, only the increased uptake in the penile shaft base on the whole-body PET-CT study yielded a diagnosis of primary penile chondrosarcoma after biopsy. …"
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Nanospace-engineered carbons for reversible storage of natural gas and hydrogen
منشور في 2011"…Excess adsorption dominated by KOH:C ratio. 2.Volumetric storage capacity decreases with increasing activation temperature. 3. 2.5K activated at 700 oC has record volumetric storage capacity of 132 g CH4/liter carbon at 35 bar and 22 oC (200 V/V, 110% of DOE target of 118 g/liter). …"
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A 75-year-old female with hemoptysis and recurrent respiratory infections
منشور في 2013"…She subsequently had multiple episodes of cough, fevers, and possible pneumonia treated with multiple courses of Amoxicillin and Amoxicillin/Clavulanate. Review of her chest CT upon presentation to the hospital showed a large necrotic lingular infiltrate, which had been progressively increasing in size over at least one year. …"
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A Numerical Study of Heat Transfer and Fluid Flow in a Channel with an Array of Pin Fins in Aligned and Staggered Configurations
منشور في 2018"…The pressure coefficient, C p , showed a developing region close to the inlet and a fully developed region as the number of fin rows is increased. …"
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Impact of the COVID-19 pandemic on sexually transmitted infection testing and diagnosis in Lebanon: A retrospective chart review
منشور في 2024"…We explore the impact of the pandemic on SHS delivery and the diagnosis rate of sexually transmitted infections (STIs) among attendees of a large sexual health clinic in Beirut, Lebanon. MethodsThis was a retrospective analysis of the clinic's database, including data on voluntary counseling and testing (VCT) for HIV, syphilis, hepatitis B virus (HBV), and hepatitis C virus (HCV). …"
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