Image 1_Asperosaponin VI suppresses ferroptosis in chondrocytes and ameliorates osteoarthritis by modulating the Nrf2/GPX4/HO-1 signaling pathway.pdf by Zhimeng Zhang (4688509)

“…In vivo experiments demonstrated that AVI improved the bone volume/tissue volume and trabecular separation values in OA rats; reversed the Osteoarthritis Research Society International score; upregulated Nrf2, HO-1, and GPX4 expression; downregulated ACSL4 and MMP13 expression, and decreased the serum levels of TNF-α, IL-6, and PGE2.…”

<b>Ensemble learning model identifies </b><b>adaptation classification and turning points</b><b> of river microbial communities in response to heatwaves</b> by Qian Qu (14198684)

“…,</i> Vietnam) countries are likely to change due to heatwave disturbance from 25 °C to 37 °C for consecutive days. Furthermore, the microbial communities in approximately 48.4% of the global river gauge stations are prone to fast stress inadaptation, with approximately 76.9% of these stations expected to exceed microbial adaptation after <a href="" target="_blank">heatwave disturbances</a>. …”

Supplementary file 1_Quantitative microbial taxonomy across particle size, depth, and oxygen concentration.zip by Paulina Huanca-Valenzuela (21414911)

“…Though the total concentration of organic C in particles decreased in the deep water column, the density of bacteria on large particles increased at depth. …”

Supplementary Data for Manuscript: Changes in salinity impact nitrogen removal and carbon preservation in coastal wetlands sediment by Ziyan WANG (22497905)

“…However, the overall impact on N removal and C preservation services remains unclear. Here, we used microcosm experiments to examine how a large salinity gradient (0-30 ppt) influenced pathways supporting N removal and C preservation in mangrove sediments. …”

Stable dosing regimes and linear stability analysis. by Tianyong Yao (22311889)

“…The change in mean <i>eda</i> is robust to a large range of half-lives and doses. The mean <i>eda</i> monotonically increases with both half-life and dose, with steep changes outside of the homeostatic plateau (large blue region). …”

Supplementary Material for: Primary Vitreoretinal Lymphomas: A Diagnostic Challenge. Report of two recent cases with retinal biopsies and molecular investigations in Halifax, Nova... by figshare admin karger (2628495)

Cell Stiffness and constriction factor. by Roland M. Dries (6620132)

“…The smaller gastrulas remained rounder, but the largest gastrula (256 cells) had a strong bowl-shape and large opening. (<b>E</b>) Number of endoderm. Image E shows the 256 celled blastula from row C, but now the number of endodermal cells is reduced from 58 to 36. …”

The Anti/Deicing Performance of the Low Interfacial Toughness Coating Is Enhanced: Induced Ice Crack Generation and Its Extension by Senyun Liu (5496785)

The Anti/Deicing Performance of the Low Interfacial Toughness Coating Is Enhanced: Induced Ice Crack Generation and Its Extension by Senyun Liu (5496785)

Physiological and behavioural aspects of climate change vulnerability in ground-foraging passerines inhabiting South Africa’s Tankwa Karoo desert by James Short (20291754)

“…Large-billed larks displayed a thermoregulatory capacity comparable to that associated with most desert birds studied to date, possessing a MaxTb of ~ 45°C and an HTL of ~50°C. …”

Data Sheet 1_Increased circulating levels of SP-D and IL-10 are associated with the development of disease severity and pulmonary fibrosis in patients with COVID-19.pdf by Xin Pan (3712768)

“…Among the biomarkers indicative of macrophage polarization, compared to non-ARDS patients, a significant increase in IL-10, Inducible nitric oxide synthase (iNOS), and Arginase-1 (Arg-1) were observed in ARDS patients, while Tumor necrosis factor-α (TNF-α) was decreased. The plasma level of IL-10 was also elevated in patients with fibrotic changes on CT, and was positively correlated with ACE2 and Arg-1. …”

Data from: Long-term changes in soil carbon and nitrogen fractions in switchgrass, native grasses, and no-till corn bioenergy production systems by Sophie Perry (9927013)

“…Declining POM N stocks likely reflect pre-establishment land use, which included alfalfa and manure in earlier rotations. Root production and large soil aggregate formation explained 69% (p < 0.001) and 36% (p = 0.024) of total soil C change, respectively, and 60% (p = 0.020) and 41% (p = 0.023) of soil N change, demonstrating the importance of belowground productivity and soil aggregates for producing and protecting soil C and conserving soil N. …”

Data Sheet 1_Spatial and temporal variability in blue carbon accumulation in the largest salt marsh in British Columbia, Canada.docx by Karen E. Kohfeld (11936879)

“…However, large spatial variability exists, with significantly lower average CARs in the east (35 ± 11 g C m^-2 yr^-1). …”

Greiser et al. (2025) Bark beetles as microclimate engineers – thermal characteristics of infested spruce trees at the canopy surface and below the canopy - Data and code by Caroline Greiser (14293763)

“…We observed that dead trees were generally warmer than living trees, by an average of 2.6 °C on a sunny day and 0.7 °C on a cloudy day.</p><p dir="ltr">Our study documented changes in thermal regimes in both the understory and overstory after bark beetle attacks, indicating that climate-change related disturbances are fueling rapid increases in microclimate warming. …”

Image1_AMPK Activation Alleviates Myocardial Ischemia-Reperfusion Injury by Regulating Drp1-Mediated Mitochondrial Dynamics.TIF by Jingxia Du (8752482)

“…However, the protection effect of Mdivi-1 was not reversed by AMPK inhibitor Compound C. In conclusion, this study confirmed that activation of AMPK exerted the protective effects on MIRI, which were largely dependent on the inhibition of Drp1-mediated mitochondrial fission.…”

DataSheet1_AMPK Activation Alleviates Myocardial Ischemia-Reperfusion Injury by Regulating Drp1-Mediated Mitochondrial Dynamics.docx by Jingxia Du (8752482)

“…However, the protection effect of Mdivi-1 was not reversed by AMPK inhibitor Compound C. In conclusion, this study confirmed that activation of AMPK exerted the protective effects on MIRI, which were largely dependent on the inhibition of Drp1-mediated mitochondrial fission.…”

Data Sheet 1_UVA-induced weathering of microplastics in seawater: surface property transformations and kinetics.docx by Liu Gao (647400)

“…The functional groups experienced stretching (e.g., -OH, C-H, C=O) and bending (e.g., X-H in-plane, C-H in-plane), as identified through Fourier transform infrared spectroscopy (FTIR). …”

Table 1_UVA-induced weathering of microplastics in seawater: surface property transformations and kinetics.xlsx by Liu Gao (647400)

“…The functional groups experienced stretching (e.g., -OH, C-H, C=O) and bending (e.g., X-H in-plane, C-H in-plane), as identified through Fourier transform infrared spectroscopy (FTIR). …”

Regular spiking neuron (sustained chopper) that exhibits accurate identification of envelope frequency from its spike trains. by Chris Scholes (3309477)

“…<b>c.</b> Classification performance, expressed as <i>c′</i> (<i>c-prime</i>; blue), has a low-pass shape across modulation frequency. …”

COMPOSITIONS AND METHODS FOR TREATMENT OF NEUROLOGICAL DISEASE by Janice Keramedjian (19726261)

“…One approach to increasing the CNS penetration of MMF is to utilize a carrier molecule that utilizes active transport proteins, such as glucose transporter 1 (GLUT1), sodium vitamin C transporter 2 (SVCT2) (Nualart, Mack et al. 2014) or large neutral amino acid transporter 1 (LAT1) (Singh and Ecker 2018). …”