Showing 1 - 20 results of 23,066 for search '(( c large increases ) OR ((( b larger decrease ) OR ( ((b marked) OR (a marked)) decrease ))))', query time: 0.68s Refine Results
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    <b>Effect of Marked Weight Loss on Adipose Tissue Biology in People with Obesity and Type 2 Diabetes</b> by Dmitri Samovski (305400)

    Published 2025
    “…</p><p dir="ltr"><b>Results: </b>Weight loss: <a href="" target="_blank">i) </a><a href="" target="_blank">decreased adipose tissue </a>expression of genes related to extracellular matrix remodeling; ii) decreased adipose tissue expression of SERPINE 1 which encodes plasminogen activator inhibitor-1 (PAI-1); iii) did not decrease adipose tissue immune cell content or expression of genes involved in inflammation; iv) decreased adipose tissue ceramide content; v) decreased plasma <a href="" target="_blank">PAI-1 </a>and leptin concentrations and increased plasma high-molecular weight (HMW) adiponectin; and vi) decreased plasma small extracellular vesicle (sEV) concentration and the sEV content of microRNAs proposed to inhibit insulin action, and completely reversed the inhibitory effect of plasma sEVs on insulin signaling in myotubes.…”
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    De-repression of gene expression and responsive histone marks. by Dana Lau-Corona (8861900)

    Published 2020
    “…<p>(<b>A</b>) Number of sites that show a significant decrease (Down) or a significant increase (Up) in each histone mark in E1/E2-KO male and E1/E2-KO female liver compared to sex-matched control liver. …”