ALS patients’ tissues exhibit increased phosphorylation of MARK2. حسب Yu-Ning Lu (10291271)

"…<p>(<b>A</b>) Representative immunoblot analyses of PKCδ, MARK2-⁵⁹⁵T, and eIF2α in the spinal cord tissues from ALS patients and non-ALS controls, indicating that increased phosphorylation of PKCδ-⁵⁰⁵T, MARK2-⁵⁹⁵T, and eIF2α-⁵¹S is a general phenotype in patient tissues. …"

The Transition from a Compensatory Increase to a Decrease in C-peptide During the Progression to Type 1 Diabetes and Its Relation to Risk حسب Heba M Ismail (9568748)

"…Conclusions</p> <p>A transition from an increase to a decrease in AUC C-peptide approximately 1.5 years pre-diagnosis was validated in two independent cohorts. …"

3D interactions between the ligand and the protein_DNA complex in the first (C1) and second (C2) clusters. حسب Ahmed A. Gaber (13302308)

الموضوعات:

Deletion of Hhp2 markedly increased Sre1 activity. حسب Hao Miao (1742044)

"…<p>Deletion of <i>hhp2</i>⁺ gene markedly increased Sre1 activity in the presence/absence of CLZ (2 μg/ml to 8 μg/ml) (A), TER (2 μg/ml to 8 μg/ml) (B) or CoCl₂ (0.08 mM to 0.32 mM) (C). …"

PLB is a target gene of miRNA 221. حسب Hongyu Li (1332669)

الموضوعات:

The influence of leucettines as DYRK1A inhibitors on insulin, C-peptide, and glucagon production by MIN6 cells. حسب Barbara Pucelik (2988795)

الموضوعات:

C-reactive protein levels in the four stages of plasmodium falciparum infection. حسب Shengshi Huang (13104571)

Increased phosphorylation of MARK2 occurs in the affected tissues of a mutant SOD1-induced ALS mouse model. حسب Yu-Ning Lu (10291271)

"…The staining of phosphorylated MARK2-⁵⁹⁵T in all 3 brain regions is increased in the SOD1^G93A mice as compared to NTg mice. …"

Non-permissive chromatin marks increase in the surviving population after T cell stimulation. حسب Birgitta Lindqvist (8378349)

Confocal imaging of MIN6 in the context of cell proliferation, as well as insulin, C-peptide, and glucagon levels after treatment with investigated leucettines. حسب Barbara Pucelik (2988795)

الموضوعات:

General procedure for the synthesis of the target compounds 11a,b,15a,b. حسب Ahmed A. Gaber (13302308)

الموضوعات:

Stress strain curves (from a1 to f1), stress—AE count plots (from a2 to f2) and stress—cumulative AE count plots (from a3 to f3) for the sample temperatures of 20°C, 50°C, 100°C, 1... حسب Nazlı Tunar Özcan (14833635)

Withdrawal of Type I JAKinibs increased STAT phosphorylation, a phenomenon present but markedly lower in Type II JAKinibs. حسب Ilya Gurevic (1326786)

"…(A) pJAK2 peaked at time zero after exposure to baricitinib and ruxolitinib and then decreases. …"

The influence of DYRK1A inhibitors on MIN6 function: Flow cytometry analysis of insulin, C-peptide and glucagon expression in MIN6 cells. حسب Barbara Pucelik (2988795)

الموضوعات:

Chronic colitis induces marked changes in protein expression in the adult heart and blood. حسب Yanbo Tang (11457519)

"…(B) Arbitrary optical density units of the targeting proteins were normalized <i>vs</i>. α-Actin and presented as fold change. (C) Immunostaining of COL3A1 in heart sections showing COL3A1 accumulation in DSS rats. …"

Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis حسب Kristina M. Garske (11220178)

"…In summary, we identify LRIs that mark repressed regions of the genome, and these interactions increase across adipogenesis, pinpointing developmental regions that need to be repressed in a cell-type specific way for adipogenesis to proceed.…"

The influence of DYRK1A inhibitors on INS1E function: Flow cytometry analysis of insulin, C-peptide and glucagon expression in INS1E cells. حسب Barbara Pucelik (2988795)

الموضوعات:

Binding of compound 11a with DNA-Topo II complex. حسب Ahmed A. Gaber (13302308)

الموضوعات:

Prevalence of infection with (A) hepatitis B virus or (B) hepatitis C virus hepatocellular carcinoma among Medicare Part D beneficiaries, 2007–2017. حسب Joy Jiang (5483006)

الموضوعات:

The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients. حسب Tao Zhang (43681)

"…In contrast, in <i>APC</i>-mutant tissues from FAP patients, the proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases. Crypt cell levels are indicated that range from crypt bottom (level 1) to crypt top (level ~82). …"