Showing 1 - 20 results of 5,438 for search '(( c we decrease ) OR ((( _ largest decrease ) OR ( _ ((nn decrease) OR (small decrease)) ))))', query time: 0.57s Refine Results
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    Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras by Charles W. Parry (20966154)

    Published 2025
    “…Despite FDA approval for two irreversible inhibitors that target the inactive state of KRas<sup>G12C</sup>, significant unmet clinical need still exists, and the susceptibility of non-G12C mutants to inactive-state inhibition remains unclear. …”
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    Table 1_Previous treatment decreases efficacy of pralsetinib in RET fusion-positive non-small-cell lung cancer.doc by Lei Wang (6656)

    Published 2025
    “…The ARROW trial revealed that RET fusion-positive non-small-cell lung cancer (NSCLC) can benefit from pralsetinib with tolerable adverse events (AEs). …”
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