HA-MAD1 tumors have increased CIN and decreased p53. حسب Sarah E. Copeland (13951506)

Dox-inducible expression of HA-MAD1 in colon is sufficient to decrease p53 expression and cause chromosome missegregation. حسب Sarah E. Copeland (13951506)

Development of a CRISPR/Cas-Based Detection Platform for Tracking Decreased Susceptibility to Cephalosporins in Neisseria gonorrheae حسب Ziyuan Zhao (2889005)

الموضوعات:

BrdU incorporation is elevated in clrn1-/- zebrafish at 4 mpf and decreases with age. حسب Hannah J. T. Nonarath (20861735)

Loss of C1-FDX results in a reduction of the CI and CV activity. حسب Baoyin Chen (2635399)

Image 1_A rapid and naked-eye methicillin resistant Staphylococcus aureus screening method based on CRISPR/Cas12a and hybridization chain reaction.tif حسب Yayun Jiang (11556973)

"…In the presence of the DNA targets, the trans-cleavage activity of CRISPR/Cas12a is activated to cleave the trigger strand, failing HCR and leading to a decrease in the fluorescence signal. …"

Supplementary file 1_A rapid and naked-eye methicillin resistant Staphylococcus aureus screening method based on CRISPR/Cas12a and hybridization chain reaction.docx حسب Yayun Jiang (11556973)

"…In the presence of the DNA targets, the trans-cleavage activity of CRISPR/Cas12a is activated to cleave the trigger strand, failing HCR and leading to a decrease in the fluorescence signal. …"

CRISPR/RfxCas13d guide RNAs used in this study. حسب Mitchell Hayes (5334887)

Manhattan plot for genome-wide association study (GWAS) in a European population with depression. حسب Xiaomei He (795333)

Table 3_Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis.xls حسب Chunjiang Tan (7208162)

"…Among the candidate genes, knockout of COL20A1 and COL27A1 led to decreased mRNA expression of ECM components (Fibronectin and Collagen-I), as well as an increased rate of cell apoptosis. …"

Table 1_Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis.xls حسب Chunjiang Tan (7208162)

"…Among the candidate genes, knockout of COL20A1 and COL27A1 led to decreased mRNA expression of ECM components (Fibronectin and Collagen-I), as well as an increased rate of cell apoptosis. …"

Table 2_Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis.xls حسب Chunjiang Tan (7208162)

"…Among the candidate genes, knockout of COL20A1 and COL27A1 led to decreased mRNA expression of ECM components (Fibronectin and Collagen-I), as well as an increased rate of cell apoptosis. …"

Off-target analysis of CRISPR-Cas9 genome editing. حسب Zhen Zhou (184390)

CRISPR-Cas9-mediated mutation analysis of T₀ Stmc7 mutants. حسب Bikram Poudel (15989201)

Table 1_CRISPR/Cas9- and Cas3-mediated modification of copy number variation in rice.xlsx حسب Hyungjun Park (14580903)

"…Phenotypes of the copy number variants revealed OsGA20ox1 copy number as a determinant of seedling vigor in rice. The Cas3 nuclease, which induces large-scale deletions, effectively decreased the copy number of the OsMTD1 gene. …"

Image 4_CRISPR/Cas9- and Cas3-mediated modification of copy number variation in rice.jpeg حسب Hyungjun Park (14580903)

"…Phenotypes of the copy number variants revealed OsGA20ox1 copy number as a determinant of seedling vigor in rice. The Cas3 nuclease, which induces large-scale deletions, effectively decreased the copy number of the OsMTD1 gene. …"

Image 5_CRISPR/Cas9- and Cas3-mediated modification of copy number variation in rice.jpeg حسب Hyungjun Park (14580903)

"…Phenotypes of the copy number variants revealed OsGA20ox1 copy number as a determinant of seedling vigor in rice. The Cas3 nuclease, which induces large-scale deletions, effectively decreased the copy number of the OsMTD1 gene. …"

Image 1_CRISPR/Cas9- and Cas3-mediated modification of copy number variation in rice.jpeg حسب Hyungjun Park (14580903)

"…Phenotypes of the copy number variants revealed OsGA20ox1 copy number as a determinant of seedling vigor in rice. The Cas3 nuclease, which induces large-scale deletions, effectively decreased the copy number of the OsMTD1 gene. …"

Image 3_CRISPR/Cas9- and Cas3-mediated modification of copy number variation in rice.jpeg حسب Hyungjun Park (14580903)

"…Phenotypes of the copy number variants revealed OsGA20ox1 copy number as a determinant of seedling vigor in rice. The Cas3 nuclease, which induces large-scale deletions, effectively decreased the copy number of the OsMTD1 gene. …"

Image 6_CRISPR/Cas9- and Cas3-mediated modification of copy number variation in rice.jpeg حسب Hyungjun Park (14580903)

"…Phenotypes of the copy number variants revealed OsGA20ox1 copy number as a determinant of seedling vigor in rice. The Cas3 nuclease, which induces large-scale deletions, effectively decreased the copy number of the OsMTD1 gene. …"